Effect of Pruritus on Sleep Quality in Individuals Undergoing Hemodialysis Effect of Pruritus on Sleep Quality
Introduction: Although uremic pruritus is not a life-threatening problem itself, it affects the quality of life and daily life activities of the patients and negatively changes the patient's adaption to the disease.
Methods: This descriptive and analytical study was conducted with 219 patients who underwent hemodialysis in State Hospital, University Hospital hemodialysis units and a private dialysis center and met the study criteria. Research data were collected using the Introductory Information Form, 5-D Pruritus Scale and Pittsburg Sleep Quality Index. In the analysis of the data, t test, One - Way ANOVA test, Mann-Whitney U test, Kruskal-Wallis T test, Perason correlation analysis and Dunnet T3 Post Hoc test were used.
Results: In the study, the 5-D Pruritus Scale mean score of the patients was 12.70±3.35 points, and the Pittsburg Sleep Quality Index score was 12.82±2.42. A positive, moderately significant (r=.509, p
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- [1] Akyol A, Yurdusever S, Temizkan A, Sifil H, Ecder T. Hemodiyaliz
hastalarının uyku sorunlarına etki eden faktörlerin incelenmesi.
Nefroloji Hemşireliği Dergisi 2017; 2(12):49-57. (Turkish)
- [2] Topbaş E, Bingöl G. Psikososyal boyutu ile diyaliz tedavisi
ve uyum sürecine yönelik hemşirelik girişimleri. Nefroloji
Hemşireliği Dergisi 2017; 1(12):36-42. (Turkish)
- [3] Kavurmacı M, Tan M. Üremik kaşıntı ve hemşirelik bakımı.
Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi 2014; 18(1):57-
62. (Turkish)
- [4] Olıveıra M, Pıgarı VG, Ogata M, Mıot HA, Ponce D, Abbade
L. Gabapentin versus dexchlorpheniramine as treatment for
uremic pruritus:a randomised controlled trial. Eur J Dermatol
2018; 28(4):488-495.
- [5] Mettang T, Kremer EA. Uremic pruritus. Kidney Int. 2015;
87(4):685-691.
- [6] Min J, Kim S, Kim Y, Jin D, Song H, Choi E, Kim Y, Kim Y, Kang S,
Kim N, Yang C, Kim Y. Comparison of uremic pruritus between
patients undergoing hemodialysis and peritoneal dialysis.
Kidney Res and Clin Pract. 2016; 35:107-113.
- [7] Du T, Barhen A, Bhatia JS, Wolpowitz D. Loss of papillary
dermal calcitonin gene related peptide – expressing neurons
significantl correlates with uremic pruritus. J Invest Dermatol.
2016; 136(11):2323-2325.
- [8] Hindistan S, Deniz A. Hemodiyaliz tedavisi alan hastalarda
semptom değerlendirmesi. Bezmialem Science 2018; 6:112-
118. (Turkish)
- [9] Simonsen E, Komenda P, Lemer B, Askin N, Bohm C, Shaw J,
Tangri N, Rigatto C. Treatment of uremic pruritus:a systematic
review. Am J Kidney Dis 2017; 70(5):638-655.
- [10] Ersoy NA, Akyar İ. Kronik böbrek yetmezliği olan hastalarda
5-D kaşıntı ölçeğinin geçerlilik güvenirlik çalışması. Acıbadem
Univ. Sağlık Bilim. Derg 2017; 9(4):455-461. (Turkish)
- [11] Pereira M, Stander S. Assenssment of severity and burden of
pruritus. Allergol Int. 2017; 66:3-7.
- [12] Velioğlu P. Hemşirelikte Kavram ve Kuramlar. 2. Baskı. İstanbul:
Akademi Basın; 2012. s.528. (Turkish)
- [13] Inui S. Nalfurafine hydrochloride to treat pruritus: a review.
Clin Cosmet Investig Dermatol. 2015; 8:249-255.
- [14] Rehman IU, Chia D, Ahmed R, Khan N, Rahman A, Munib
S, Lee L, Chan K, Khan T. A randomized controlled trial for
effectiveness of zolpidem versus acupressure on sleep
in hemodialysis patients having chronic kidney disease –
associated pruritus. Medicine 2018; 97(31):1-6.
- [15] Jin D, Shen H, Feng S, Zhan Z, Jiang L, Qiu B, Zeng Y, Shi Y.
Treatment effects of different ıncident dialysis modalities on
pruritus in elderly uremic patients. Int J Gerontol. 2014; 8:223-
227.
- [16] Elman S, Hynan LS, Gabriel V, Mayo MJ. The 5-D itch scale: a
new measure of pruritus. Br J Dermatol 2010; 162(3):587-593.
- [17] Buysse DJ, Reynolds CF, Monk TH. The Pittsburgh sleep quality
ındex: a new instrument for psychiatric practice and research.
Psychiatry Res. 1989; 28(2):193-213.
- [18] Ağargün MY, Kara H, Anlar O. Pittsburg uyku kalitesi indeksinin
geçerliği ve güvenirliği. Türk Psikiyatri Derg. 1996; 7:107-111.
(Turkish)
- [19] Güder S, Karaca Ş, Kulaç M, Yüksel Ş, Güder H. Afyonkarahisar ve
çevresinde diyalize giren kronik böbrek yetmezlikli hastalarda
deri bulguları. Türkderm 2012; 46:181-185. (Turkish)
- [20] Ko MJ, Peng Y, Chen H, Hsu SP, Pai MP, Yang JY, Wen SY, Jee
SH, Wu HY, Chiu HC. Interleukin-31 is associated with uremic
pruritus in patients receiving hemodialysis. J Am Acad
Dermatol. 2014; 71(6):1151-1159.
- [21] Küçükünal A, Altunay İA, Salman KE, Atış G. Hemodiyaliz
hastalarında üremik pruritis ve yaşam kalitesi ilişkisi. Türkderm
2015; 49(1):23-27. (Turkish)
- [22] Sukul N, Wang M, Bieber B, Li Y, Lopes AA, Speyer E, Stengel B.
Prurıtıs ın chronıc kıdney dısease patıents: early results from
CKDOPPS. Nephrol Dial Transplant. 2016; 31(1):187.
- [23] Akhyani M, Ganji MR, Samadi N, Khamesan B, Daneshpazhooh
M. Pruritus in hemodialysis patients. BMC Dermotol. 2005;
5(7):1-6.
- [24] Shavit L, Grenader T, Lifschitz M, Slotki I. Use of pregabalin in
the management of chronic uremic pruritus. J Pain Symptom
Manage. 2012; 45(4):776-781.
- [25] Taskapan H, Ates F, Kaya B, Emul M, Kaya M, Taskapan Ç,
Şahin İ. Psychiatric disorders and large interdialytic weight
gain in patients on chronic haemodialysis. Nephrology 2005;
10(1):15-20.
- [26] Indrarini A, Zahra AN, Yona S. The relationship between
anemia, depression, duration of hemodialysis and quality of
sleep among end-stage renal disease patients. Enferm Clin.
2019; 29(2):24-29.
- [27] Shen Q, He Q. Sleep quality, anxiety and quality of life in stable
hemodialysis patients. Hong Kong J Nephrol 2015; 17(2):129.
- [28] Sert F, Demir AB, Bora İ, Yıldız A, Ocakoğlu G, Ersoy A.
Kronik renal yetmezlikli ve böbrek nakilli hastalarda uyku
bozukluğunun araştırılması ve bunun yaşam kalitesi üzerine
etkisi, J Turk Sleep Med. 2015; 1:15-19. (Turkish)
- [29] Pierratos A, Hanly PJ. Sleep disorders over the full range of
chronic kidney disease. Blood Purif 2011;31:146-150
- [30] Elder SJ, Pisoni RL, Akizowa T, Fissell R, Andrucci V, Fukuhara S,
Kurokawa K, Rayner H, Furniss A, Port F, Saran R. Sleep quality
predicts quality of life and mortality risk in haemodialysis
patients: results from the dialysis outcomes and practice
patterns study. Nephrol Dial Transplant 2008; 23:998-1004.
- [31] Ricardo A, Vivien G, Chen J, Couvert E, Kapella M, Prased
B, Parvathaneni S, Knutson K, Lash J. Association of sleep
duration, symptoms and disorders with mortality in adults
with chronic kidney disease. Kidney Int Rep 2017; 2:866-873.
- [32] Karadağ E, Kılıç SP, Karatay G. Effect of baby oil on pruritus,
sleep quality and quality of life in hemodialysis patients:
pretest-post-test modeş with control groups. Jpn J Nurs Sci.
2014; 11:180-189