The Relationship of Hemogram and Inflammatory Biomarkers to Lenght of Stay in Hospital and Clinical Course in Patients with COVID-19

Objective: It was aimed to research the relationship between neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), inflammatory markers and lenght of stay in hospital (LOS) with clinical results in hospitalized patients with Coronavirus disease-2019 (COVID-19). Methods: Total leukocyte, neutrophil, lymphocyte and platelet counts (/mm3 ), hemoglobin (g/dL), mean platelet volume, C-reactive protein (CRP) (mg/L), ferritin (ng/mL), lactate dehydrogenase (LDH) (U/L) creatine kinase (U/L), D-dimer (ng/mL), troponin-I (pg/mL), alanine aminotransferase (U/L), aspartate aminotransferase (U/L) and serum creatinine (mg/dL) measurements were recorded. NLR and PLR were calculated. Applied treatments, intensive care unit requirement, and mortality rates were determined. For LOS and mortality, the sensitivity of biochemical parameters was evaluated. Results: One hundred seventy-one patients (87 females, 84 males) were evaluated. The mean age was 57.9±14.6 years, and the mean LOS was 8.83±6.4 days. There was a positive correlation between NLR and PLR (p

COVİD-19 Olgularında Hemogram ve Enflamasyon Biyobelirteçlerinin Hastane Yatış Süresi ve Klinik Seyirle Ilişkisi

Amaç: Hospitalize Coronavirüs hastalığı-2019 (COVİD-19) olgularında nötrofil-lenfosit oranı (NLR), platelet-lenfosit oranı (PLR) ve enflamatuvar göstergelerin hastane yatış süresi (HYS) ve klinik seyirle olan ilişkisini araştırmaktır. Yöntemler: Çalışmaya dahil edilen olguların total lökosit, nötrofil, lenfosit ve trombosit sayıları (/mm3 ), hemoglobin düzeyi (g/dL), ortalama trombosit hacmi, C-reaktif protein (CRP) (mg/L), ferritin (ng/mL), laktat dehidrogenaz (LDH) (U/L), kreatin kinaz (U/L), D-dimer (ng/mL), troponin-I (pg/mL), alanin aminotransferaz (U/L), aspartat aminotransferaz (U/L) ve serum kreatinin (mg/ dL) sonuçları kaydedildi. NLR ve PLR hesaplandı. Uygulanmış olan antiviral tedaviler kaydedildi. Yoğun bakım ünitesi takibi ve mortalite oranları belirlendi. Biyokimyasal parametrelerin kendi aralarındaki korelasyon analizleri yapıldı ve parametrelerin HYS ve mortalite öngörüsü için duyarlılıkları analiz edildi. Bulgular: Toplam 171 hastanın (87 kadın, 84 erkek) verileri değerlendirildi. Ortalama yaş 57,9±14,6 yıl, ortalama HYS 8,83±6,4 gündü. NLR ile PLR pozitif yönde koreleydi (p

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Kaynak Göster

  • ISSN: 2148-2373
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2013
  • Yayıncı: Galenos Yayınevi

4.9b 2.3b

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