Özgür KEMİK, Sevim PURİSA, İshak Sefa TÜZÜN, Ahmet Fikret YÜCEL, Ahu KEMİK SARBAY

Relationship between the levels of oxidative stress in mesenteric and peripheral serum and clinicopathological variables in colorectal cancer

Amaç: Kolorektal kanserli hastalarda, periferik ve mezenterik serum oksidatif stres düzeyleri arasındaki farkları göstermek. Gereç ve Yöntemler: Mayıs 2005-Mart 2010 yılları arasında kolorektal kanser nedeniyle cerrahi uygulanan 150 hasta prospektif olarak incelendi. Periferik ve mezenterik kandaki oksidatif stres parametreleri arasındaki farklar ölçüldü. Klinik, patolojik ve tümör evresine göre ilişkileri araştırıldı. Bulgular: İleri evre (p

Kolorektal kanserli hastalarda klinikopatolojik özellikler ile periferik ve mezenterik serum oksidatif stres düzeyleri arasındaki ilişki

Objective: To explore the differences existing between the levels of oxidative stress in peripheral and mesenteric serum in patients with colorectal cancer. Material and Methods: One hundred fifty patients with colorectal cancer who underwent surgery between May 2005 and March 2010 were prospectively analyzed. The differences between oxidative stress parameters in their peripheral and mesenteric blood were measured. The associations between peripheral and mesenteric levels and the staging and clinicopathological variables were investigated. Results: Oxidative stress parameters were higher in patients with advanced tumor staging (p

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