Selim SÖZEN, Salih DEMİRELLİ, Abdullah BÖYÜK, Cüneyt KIRKIL, Koray KARABULUT

A choledochal cyst resulting in obstructive jaundice in a case with gallbladder agenesis: Report of a case and review of the literature

Co-existence of gallbladder agenesis and choledochal cyst is a very rare congenital anomaly of the extrahepatic biliary system. The literature presents only five cases with this combination. Herein, we report the sixth case. Gallbladder agenesis is usually asymptomatic, while choledochal cyst often presents symptoms before adolescence. This is the report of a 42-year-old female patient with gallbladder agenesis and choledochal cyst leading to obstructive jaundice. Radiological diagnosis of choledochal cysts is not difficult. However, in cases with gallbladder agenesis, cystic dilatation in the choledochus may be misdiagnosed as mislocation of the gallbladder or contracted and/or sclero-atrophic gallbladder.

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1. Fiaschetti V, Calabrese G, Viarani S, Bazzocchi G, Simonetti G. Gallbladder agenesis and cystic duct absence in an adult patient diagnosed by magnetic resonance cholangiography: report of a case and review of the literature. Case Report Med 2009;2009:674768.
2. Gotohda N, Itano S, Horiki S, Endo A, Nakao A, Terada N, et al. Gallbladder agenesis with no other biliary tract abnormality: report of a case and review of the literature. J Hepatobiliary Pancreat Surg 2000;7:327-30. [CrossRef]
3. Tabibian JH, Tabibian N, Aguet JC. Choledochal cyst complications presenting as duodenal obstruction in an 82-year-old patient with gallbladder agenesis. Dig Dis Sci 2009;54:184-7. [CrossRef]
4. Goel AK, Seenu V, Khosla NK, Gupta A, Sarda AK. Agenesis of gallbladder with choledochal cyst--an unusual combination. Trop Gastroenterol 1994;15:33-6.
5. Todani T, Watanabe Y, Narusue M, Tabuchi K, Okajima K. Congenital bile duct cysts: classification, operative procedure and review of 37 cases including cancer arising from choledochal cyst. Am J surg 1977;134:263-9. [CrossRef]
6. Latimer EO, Mendez FL, Hage WJ. Congenital absence of gallbladder: report of three cases. Ann Surg. 1947;126:229-42. [CrossRef]
7. Bennion RS, Thompson JE, Tompkins RK. Agenesis of the gallbladder without extrahepatic biliary atresia. Arch Surg 1988;123:1257-60. [CrossRef]
8. Frey C, Bizer L, Ernst C. Agenesis of the gallbladder. Am J Surg 1967;114:917-26. [CrossRef]
9. Bani-Hani KE. Agenesis of the gallbladder: difficulties in management. J Gastroenterol Hepatol. 2005;20:671-5. [CrossRef]
10. Singham J, Yoshida EM, Scudamore CH. Choledochal cysts: part 1 of 3: classification and pathogenesis. Can J Surg. 2009;52:434-40.
11. Chaturvedi A, Singh J, Rastogi V. Case report: Cholangiocarcinoma in a choledochal cyst. Indian J Radiol Imaging 2008;18:236-8. [CrossRef]