Comparison of Vitamin D Levels in Allergic Patients with and Without Asthma

Objective: To determine whether serum vitamin D levels had a relationship with pulmonary function test (PFT) results and serum immunoglobulin E (IgE) levels in allergic patients with and without asthma. Method: The study group was comprised of patients who had positive allergy skin tests with and without asthma (n=31, n=28, respectively) and healthy controls (n=31). The skin allergy test (prick test) and PFT were performed on all of the study groups. Also, the patients’ serum vitamin D and IgE levels were determined. Comparisons among these groups and also subgroups of the patients were investigated in addition to correlation analyses for vitamin D, IgE and PFT results. Results: Seventy percent of the asthma group was found to have abnormal PFT results, while all healthy controls and non-asthmatic patients had normal PFT results (p

Astım Tanısı Olan ve Olmayan Allerjik Hastalarda Vitamin D Seviyelerinin Karşılaştırılması

Amaç: Astım tanısı olan ve olmayan alerjik hastalarda D vitamini düzeylerinin solunum fonksiyon testi (SFT) sonuçları ve serum immünoglobulin E (IgE) düzeyleri ile ilişkisinin belirlenmesi amaçlandı. Yöntem: Çalışma grubu, alerjik cilt testi pozitif olan astımı olan ve olmayan hastalardan (sırasıyla n=31, n=28) ve sağlıklı kontrollerden (n=31) oluşuyordu. Tüm çalışma grubuna cilt alerji testi (prick testi) ve SFT uygulandı. Ayrıca, hastaların serum vitamin D ve IgE seviyeleri belirlendi. Vitamin D, IgE ve SFT sonuçları arasındaki korelasyon analizlerine ek olarak bu gruplar ve hasta alt grupları arasında karşılaştırmalar yapıldı. Bulgular: Astım grubunun %70’inde anormal SFT sonuçları saptanırken, tüm sağlıklı kontroller ve astımlı olmayan hastalar normal SFT sonuçlarına sahipti (p

Kaynakça

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