MRI and Anesthesia & Sedation

MRI and Anesthesia & Sedation

In 1945 Broch & Purcell described as Nuclear Magnetic Resonance. It wasused for chemical and biochemical analyses for long years. It was widelyused in medical applications after Lauterbur et al. ‘s study in 1973 (1).The primary screening method for breast cancer is mammography asknown. It is the only method that positively affects survival. But itssensitivity and specificity is not 100% and it can be an inadequate methodat some ages. Studies showed that: MRI imaging added mammographyincreased success rates but increased false positivity rates can cause someunnecessary invasive procedures. Although these breast MRI is widely usedfor screening, diagnosis and staging (2).More than 80 million MRI is worldwide applied yearly. Claustrophobia ratesare between 1-15% and more than 2 million breast MRI application isinterrupted for the necessitation of sedation (3). Melendez et al. noticedthat rate around 30%. Also 3-5% of these cases were interrupted due tothe sedation necessitation. Anxiety and claustrophobia can cause sequencerepeating, procedure cancellation and important time and labor loss.

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  • 1. Bloch F, Hansen WW, Packard M. Nuclear induction. Phys Rev 1946;69:127.
  • 2. Menon DK, Peden CJ, Hall AS, Sargentoni J, Whitwam JG. Magnetic resonance for the anaesthetist. Part I: Physical principles, applications, safety aspects. Anaesthesia. 1992 Mar;47(3):240-55. Review.
  • 3. Health Quality Ontario. Magnetic Resonance Imaging as an Adjunct to Mammography for Breast Cancer Screening in Women at Less Than High Risk for Breast Cancer: A Health Technology Assessment. Ont Health Technol Assess Ser. 2016 Nov 1;16(20):1-30. eCollection 2016.
  • 4. Enders J, Zimmermann E, Rief M, Martus P, Klingebiel R, Asbach P, Klessen C, Diederichs G, Bengner T, Teichgräber U, Hamm B, Dewey M. Reduction of claustrophobia during magnetic resonance imaging: methods and design of the "CLAUSTRO" randomized controlled trial. BMC Med Imaging. 2011 Feb 10;11:4. doi: 10.1186/1471-2342-11-4.
  • 5. Meléndez JC1, McCrank E. Anxiety-related reactions associated with magnetic resonance imaging examinations. JAMA 1993;270:745-7.
  • 6. Munn Z, Jordan Z. Interventions to reduce anxiety, distress and the need for sedation in adult patients undergoing magnetic resonance imaging: a systematic review. Int J Evid Based Healthc. 2013 Dec;11(4):265-74. doi: 10.1111/1744-1609.12045.
  • 7. Barnea-Goraly N, Weinzimer SA, Ruedy KJ, Mauras N, Beck RW, Marzelli MJ, et al. High success rates of sedation-free brain MRI scanning in young children using simple subject preparation protocols with and without a commercial mock scanner–the Diabetes Research in Children Network (DirecNet) experience. Pediatr Radiol 2014;44:181–6.
  • 8. Metzner J, Posner KL, Lam MS, Domino KB. Closed claims' analysis. Best Pract Res Clin Anaesthesiol 2011;25:263-76.