Anorectal malignant melanoma: A case report and treatment options

Anorectal malignant melanoma (AMM) is a rare malignant disease with a poor prognosis. This disease is often confused with hemorrhoids. The most common site of malignant melanoma following skin and eye involvement is the anorectal region. This is the most commonly involved site in the gastrointestinal tract. We report the case of a 67-year-old patient with lower gastrointestinal hemorrhage for 4 months and hemorrhoid treatment for 2 months. The imaging revealed no distant metastasis but histopathologically, lymph node metastasis and invasion of surrounding tissues. Laparoscopic abdominoperineal resection (APR) was performed.

Anorektal malign melanom: Bir olgu sunumu ve tedavi seçenekleri

Anorektal melanom ( AMM ) ender görülen, kötü prognozlu malign bir hastalıktır. Bu hastalık sıklıkla hemoroid ile karışmaktadır. Malign melanomanın deri ve göz tutulumundan sonra en sık görüldüğü bölge anorektal bölgedir. Bu bölge gastrointestinal sistemde en sık olarak tutulan bölgedir. Biz 67 yaşında, 4 aydır makattan kanama şikayetleri olan, 2 aydır da hemoroid tedavisi uygulanan hastayı sunduk. Yapılan görüntülemelerde hastanın uzak metastazının olmadığı ancak histopatolojik olarak lenf nodu metastazının ve çevre dokulara invazyonun olduğu izlendi. Hastaya laparoskopik abdominoperineal rezeksiyon ( APR ) yapıldı.

Kaynakça

1. Yap LB, Neary P. A comparison of wide local excision with abdominoperineal resection in anorectal melanoma. Melanoma Res. 2004;14:147-50.

2. Meguerditchian AN, Meterissian SH, Dunn KB. Anorectal melanoma: diagnosis and treatment. Dis Colon Rectum. 2011;54:638-4.

3. Damodaran O, Morgan A, Mendelsohn G. Primary malignant melanoma in the anorectum: an uncommon cancer. N Z Med J. 2008;121:66-8.

4. Yeh JJ, Shia J, Hwu WJ, et al.The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Ann Surg. 2006;244:1012-17.

5. Thibault C, Sagar P, Nivatvongs S, Ilstrup DM, Wolff BG. Anorectal melanoma - an incurable disease. Dis Colon Rectum. 1997;40:661-8.

6. Malik A, Hull T, Floruta C. What is the best surgical treatment for anorectal melanoma? Int J Colorectal Dis. 2004;19:121-23.

7. Fazio VW, Church JM, Delaney CP. Current therapy in colon and rectal curgery. Second Edition. Philadelphia: Elsevier Mosby 2005;79-81.

8. Pessaux P, Pocard M, Elias D, et al.Surgical management of primary anorectal melanoma. Br J Surg. 2004;91:1183-7.

Kaynak Göster

367 203

Arşiv
Sayıdaki Diğer Makaleler

Radiologically guided percutaneous nephrostomy: A 6-year single-center experience

Mehmet ŞEKER, Türkmen Turan ÇİFTÇİ, Devrim AKINCI, Okan AKHAN

Anorectal malignant melanoma: A case report and treatment options

Hacı Hasan ABUOĞLU, Mehmet GENÇTÜRK, Mehmet Kamil YILDIZ, Onur İLHAN, Mehmet GULMEZ, Kübra KAYTAZ, Selvinaz ÖZKARA

An effective minimal invasive method in pilonidal sinus surgery: Sinusotomy

Önder KARABAY

Effect of palmitate-induced steatosis on paraoxonase-1 and paraoxonase-3 enzymes in human-derived liver (HepG2) cells

GÜLBEN SAYILAN ÖZGÜN, ERAY ÖZGÜN, KIYMET TABAKÇIOĞLU, SELMA SÜER GÖKMEN, Sevgi ESKİOCAK

Does the measurement of the size of the first trimester subchorionic hematoma by 2D and 3D ultrasonographic techniques have any effect on adverse pregnancy outcomes?

SİBEL ÖZLER, Basak Gumus GULER

The effects of mesenchymal stem cells on the IDO, HLA-G and PD-L1 expression of breast tumor cells MDA-MB-231 and MCF-7

Rabia Bilge ÖZGÜL ÖZDEMİR, Alper Tunga ÖZDEMİR, Cengiz KIRMAZ, Mehmet İbrahim TUĞLU, Özgür ŞENOL, Cenk Serhan ÖZVEREL, Afig BERDELİ

Protective effects of N-acetylcysteine and taurine on oxidative stress induced by chronic acetaldehyde administration in rat liver and brain tissues

Zeynep DİCLE YILDIZ, Adile Merve BAKİ, Canan BAŞARAN KÜÇÜKGERGİN, Pervin VURAL, Semra Doğru ABBASOĞLU, Müjdat UYSAL

Determination of galectin-3, hepsin (Tmprss 1) and thyroid transcription factor-1 levels in thyroid cancer patients: A prospective case-control study

Ufuk MEMİŞ, ERDEM KARADENİZ, Müfide Nuran AKÇAY, Nurinnisa ÖZTÜRK

Successful management of lower rectal carcinoma recurrence on perineal pseudo-continent colostomy: A case report and review of literature

Malek BOUHANİ, Olfa JAIDANE, Mohamed Amine BOUIDA, Radhi BENNACEUR, Riadh CHARGUI, Khaled RAHAL