The investigation of clinical and radiological findings of hepatic alveolar cyst hydatid disease

The investigation of clinical and radiological findings of hepatic alveolar cyst hydatid disease

Aim: The aim of this study is to investigate the clinical and radiological findings of hepatic alveolar hydatid cyst diagnosed in our clinic.Material and Methods: Records of patient files with histological diagnosis of hepatic alveolar hydatid cyst between March 2013 and February 2018 were retrospectively reviewed. Fifteen cases were included in the study. Nine of the cases were males (60 %) and 6 were females (40 %). Their ages ranged from 27 to 62 with a mean age of 41 ± 7.3 years. Clinical and laboratory findings and radiological imaging findings of the cases were investigated and recorded.Results: The most common symptoms were right upper quadrant pain (75 %), jaundice (24 %), fever (13 %) and weight loss (12 %). The most common finding in physical examinations was hepatomegaly (96 %). AST, ALT, and ALP values increased 3-4 times. Bilirubin values were generally increased (0.8-21.2 mg/dL). Abdominal ultrasonography (US) was described as a mass lesion with irregularly border, heterogeneous echogenicity, which consisted of the most solid component. It was located in the right liver lobe (82 %). Multislice Computed Tomography (MSCT) and Magnetic Resonance Imaging (MRI) findings supported the US findings. There was no contrast material involvement in the lesion. Diffusion MRI showed mild diffusion restriction somewhere.Conclusions: Alveolar echinococcosis frequently confused with other malignant liver lesions. Early diagnosis of the disease is very important in terms of treatment. Immunologic tests and biopsy are helpful in diagnosis. Radiological findings have an important role and contribution in the diagnosis of the disease.

___

  • Akın O, Isıklar I. Hepatic alveolar echinococcosis. Acta Radiol 1999;40:326-8.
  • Choji K, Fujita N, Chen M, et al. Alveolar hydatid disease of the liver: computed tomography and transabdominal ultrasound with histopathological correlation. Clin Radiol 1992;46:97-103.
  • Pohnan R, Ryska M, Hytych V, et al. Echinococcosis mimicking liver malignancy: a case report. Int J Surg Case Rep 2017;36:55-8.
  • Caire Nail L, Rodríguez Reimundes E, Weibel Galluzzo C, et al. Disseminated alveolar echinococcosis resembling metastatic malignancy: a case report. J Med Case Rep 2017;11:113.
  • Barosa R, Pinto J, Caldeira A, et al. Modern role of clinical ultrasound in liver abscess and echinococcosis. J Med Ultrason 2017;44:239-45.
  • Cai DM, Wang HY, Wang XL, et al. Ultrasonographic findings of small lesion of hepatic alveolar echinococcosis. Acta Trop 2017;174:165-70.
  • Sade R, Kantarci M, Genc B, et al. Computed tomography perfusion imaging for the diagnosis of hepatic alveolar echinococcosis. Eurasian J Med 2018;50:1-5.
  • Claudon M, Bessieres M, Regent D, et al. Alveolar echinococcosis of the liver: MR findings. J Comput Assist Tomogr 1990;14:608-14.
  • Zheng J, Wang J, Zhao J, et al. Diffusion-Weighted MRI for the initial viability evaluation of parasites in hepatic alveolar echinococcosis: comparison with positron emission tomography. Korean J Radiol 2018;19:40-6.
  • Sade R, Kantarci M, Ogul H, et al. Differentiation between hepatic alveolar echinococcosis and primary hepatic malignancy with diffusion-weighted magnetic resonance imaging. Diagn Interv Imaging 2018;99:169-77.
  • Qu B, Guo L, Sheng G, et al. Management of Advanced Hepatic Alveolar Echinococcosis: Report of 42 Cases. Am J Trop Med Hyg 2017;96:680-5.
  • Fattahi Masoom SH, Lari SM, Fattahi AS, et al. Albendazole therapy in human lung and liver hydatid cysts: a 13-year experience. Clin Respir J 2018;12:1076-83.
  • Aliakbarian M, Tohidinezhad F, Eslami S, Liver transplantation for hepatic alveolar echinococcosis: literature review and three new cases. Infect Dis 2018;50:452-9.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi