Prevalence and severity of non-traumatic acute kidney injury in multiple trauma patients attending emergency department

Prevalence and severity of non-traumatic acute kidney injury in multiple trauma patients attending emergency department

Aim: Early prediction of acute kidney injury in multiple trauma patients to decrease its sequel and begin early treatment to improveoutcome. Acute kidney injury (AKI) is an uncommon but serious complication after trauma. In large trauma victims, the incidence ofpost-traumatic AKI varies from 0.098 to 8.4% in published series with mortality ranging from 7 to 83%.Patients who develop AKI have a high mortality rate, especially when requiring dialysis with rates ranging from 37% to 88%. Therehas been progressive technical and scientific development in patient care towards AKI prevention.Material and Methods: This study is prospective study conducted in emergency department (ED) and randomly selected 270 multipletrauma patients at Suez Canal university hospital from them 21 patients developed acute kidney injury. And select according theInclusion criteria and exclusion criteria.Results: All included 270 patients with multiple trauma 21 (7.7%) developed AKI and 3 (1.1%) of them required dialysis with mortalityrate of (38%). 88.50% of multiple trauma patients were suffering from head trauma and (50.30%) were having abdominal injury while36.80% were suffering from orthopedic trauma. And patients were developed AKI divided into 3 stages; stage one (5.20%), stage two(1.50%), and stage three (1.10%).Conclusion: Majority of studied patients were have normal creatinine level at time of arrival, after 24hrs some patients developedacute kidney injury and the most common cause was hypovolemic shock while the most common cause of mortality in acute kidneyinjury was septic shock.

___

  • 1. Mock CN, Jurkovich GJ, Arreola-Risa C, et al. Trauma mortality patterns in three nations at different economic levels: implications for global trauma system development. Journal of Trauma and Acute Care Surgery 1998;44:804-14.
  • 2. Rahimi-Movaghar V. Controlled evaluation of injury in an international Safe Community: Kashmar, Iran. Public Health 2010;124:190-7.
  • 3. Odero W, Garner P, Zwi A. Road traffic injuries in developing countries: a comprehensive review of epidemiological studies. Tropical Medicine & International Health 1997;2:445-60.
  • 4. Molitoris BA, Levin A, Warnock DG, et al. Acute Kidney Injury Network. Improving outcomes from acute kidney injury. J Am Soc Nephrol 2007;18:1992-4.
  • 5. Regel G, Lobenhoffer P, Grotz M, et al. Treatment results of patients with multiple trauma: an analysis of 3406 cases treated between 1972 and 1991 at a German Level I Trauma Center. Journal of Trauma and Acute Care Surgery 1995;38:70-8.
  • 6. Mehta RL, Kellum JA, Shah SV, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Critical care 2007;11:31.
  • 7. Thadani R, Pascual M and Bonventre JV. Acute renal failure. N Engl J 1996;30:1448-59.
  • 8. Vetterlein FR, Petho A, Schmidt GE. Distribution of capillary blood flow in rat kidney during postischemic renal failure. American Journal of Physiology-Heart and Circulatory Physiology1986;251:510-9.
  • 9. Eriksson M, Brattström O, Mårtensson J, et al. Acute kidney injury following severe trauma: risk factors and long-term outcome. journal of trauma and acute care surgery. 2015;79:407-12.
  • 10. Gomes E, Antunes R, Dias C et al. Acute kidney injury in severe trauma assessed by RIFLE criteria: a common feature without implications on mortality. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine2010.;18:1-6.
  • 11. Sean M. Bagshaw, Carol George, R.T. Noel Gibney & Rinaldo Bellomo.2010.A Multi-Center Evaluation of Early Acute Kidney Injury in Critically Ill Trauma Patients
  • 12. Lai WH, Rau CS, Wu SC, et al. Post-traumatic acute kidney injury: a cross-sectional study of trauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2016 22;24:136.
  • 13. de Abreu KL, Silva GB, Barreto AG, et al. Acute kidney injury after trauma: Prevalence, clinical characteristics and RIFLE classification. Indian Journal of Critical Care Medicine 2010;14:121.
  • 14. Podoll AS, Kozar R, Holcomb JB, et al. Incidence and outcome of early acute kidney injury in critically-ill trauma patients. PLoS One. 2013;8:77376.
  • 15. Bihorac A, Delano MJ, Schold JD, et al. Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients. Annals of surgery. 2010;252:158.
  • 16. Baitello AL, Marcatto G, Yagi RK. Risk factors for injury acute renal in patients with severe trauma and its effect on mortality. Jornal Brasileiro de Nefrologia 2013;35:127-31.
  • 17. Elbaih AH et al., Sepsis patient evaluation emergency department (SPEED) score & mortality in emergency department sepsis (MEDS) score in predicting 28-day mortality of emergency sepsis patients, Chinese J Traumatology, 2019;22:316-22.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Autoimmune hemolytic anemia in children, 20 years experience of single center

Neslihan KARAKURT, Canan ALBAYRAK, Davut ALBAYRAK

Psychosocial status and sleep quality of the patients with idiopathic intracranial hypertension

Özge ÖZYÜREK, Halil ÖNDER

Prevalence and severity of non-traumatic acute kidney injury in multiple trauma patients attending emergency department

Monira Taha ISMAIL, Ramy Tarek ELSAID, Islam Mohamed ELSHABOURY, Seham Ahmed OMER

Determining effectiveness of a multi-component oral health education program model for preschool children

Gülhan KOCAMAN, Şehnaz CEYLAN, Fatma Betül KURNAZ

Severity of coronary artery disease is associated with contrast induced nephropathy in patients with impaired renal function

Serhat SIĞIRCI, Ahmet GÜRDAL, Kadriye Orta KILIÇKESMEZ

Vitronectin and prolactin levels of cervicovaginal irrigation liquid in preterm birth risk evaluation

Ebru İnci ÇOŞKUN, Salim SEZER, İsmail DAĞ, Ercan YILMAZ, Yavuz Tahsin AYANOĞLU

Prevalence of cystic echinococcosis in humans in Erzincan Province

Murat KARA, Bülent DABANLIOĞLU, İsmail DAMARCI

The prevalence and distribution of hypodontia in 9-16 years old children

Ahmet ARAS, Mehmet Sinan DOĞAN

Awareness of lymphedema risk management behaviors and associated factors among breast cancer survivors: Results from a cross-sectional survey

Sena TOLU, Pelin BASIM

Comparison of real-time PCR, indirect immunofluorescence antibody assay, and different staining techniques for the diagnosis of Pneumocystis jirovecii

Elif Gözde DURGUT, Semra KUŞTİMUR, Merve AYDIN, Ayşe KALKANCI, Funda DOĞURMAN AL