Not your “Typical Patient”: Cryptococcal meningitis in an immunocompetent adult

Not your “Typical Patient”: Cryptococcal meningitis in an immunocompetent adult

Cryptococcal meningitis is a very rare type of infection in healthy adults. Such patients may present with the symptoms of increasedintracranial pressure. Rapid diagnosis of infection, rapid intervention to reduce intracranial pressure and appropriate antifungaltherapy are important to reduce mortality. In here we report a case of cryptococcal meningitis infection. An immunocompetentpatient presented to our clinic with the complaints of headache and dizziness for a month. The findings of the physical examinationsupported with meningitis. Cryptococcus neoformans growth was observed on blood and cerebrospinal fluid culture. Despite theappropriate antifungal therapy, patient died because of the delaying in the diagnosis.

___

  • 1. Góralska K, Blaszkowska J, Dzikowiec M. Neuroinfections caused by fungi. Infection 2018;46:443-59.
  • 2. Perfect J.R. Cryptococcosis (Cryptococcus neoformans and Cryptococcus gattii). In: Bennett JE, Dolin R, Blaser MJ,eds. Mandell, Douglas, And Bennett’s Principles And Practice Of Infectious Diseases, Eighth Edition. Philadelphia 2015;2934-248.
  • 3. Rajasingham R, Smith RM, Park BJ, et al. Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. Lancet Infect Dis 2017;17:873-81.
  • 4. Hamdan N, Billon Grand R, Moreau J. Cryptococcal meningitis in an immunocompetent patient with obstructive hydrocephalus: A case report. Neurochirurgie 2018;64:324-6.
  • 5. Barreiros C, Meireles-Brandão L, Silva D, et al. Cryptococcal Meningitis in a HIV-Negative Patient. Eur J Case Rep Intern Med 2018;5:000778.
  • 6. Ming DK, Harrison TS. Cryptococcal meningitis.Br J Hosp Med (Lond) 2017;78:125-7.
  • 7. Rolfes MA, Hullsiek KH, Rhein J, et al. The effect of therapeutic lumbar punctures on acute mortality from cryptococcal meningitis. Clin Infect Dis 2014; 59:1607-14.
  • 8. Baddley JW, Thompson GR, Riley KO, et al. Factors Associated With Ventriculoperitoneal Shunt Placement in Patients With Cryptococcal Meningitis. Open Forum InfectDis 2019;6:241.
  • 9. Liu J, Chen ZL, Li M, et al. Ventriculoperitonealshunts in non-HIV cryptococcal meningitis. BMC Neurol 2018;18:58.
  • 10. Abassi M, Boulware DR, Rhein J. CryptococcalMeningitis: Diagnosisand Management Update. Curr Trop MedRep 2015;2:90-9.
  • 11. Zhao HZ, Wang RY, Wang X, Jet al. High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis. BMC InfectDis 2018;18:643.
  • 12. Zhu LP1, Wu JQ, Xu B, et al. Cryptococcal meningitis in non-HIV-infected patients in a Chinese tertiary care hospital, 1997–2007.Med Mycol 2010;48:570-9.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Cone-beam computed tomography evaluation of C-shape canals and longitudinal grooves of mandibular first and second molar teeth

İbrahim Şevki BAYRAKDAR, İsmail GÜMÜŞSOY, Şuayip Burak DUMAN, Sacide DUMAN, Yasin YASA

Comparison of two surfactant preparates derived from the same animal for the treatment of respiratory distress syndrome

Ali Ulaş TUĞCU, Deniz Anuk İNCE, Özden TURAN, Ayşe ECEVİT

Cold urticaria, the uncommon physical urticaria: Case report

Erdem TOPAL, Emrullah ARIKANOĞLU

The relationship between body mass index in late pregnancy and fetomaternal blood flow parameters: A prospective cross-sectional study

Elif Güven GÖZGEÇ, Ayşe Nur AKSOY, Tuncer NACAR

The correlation between neuropathic pain incidence and vitamin D levels in patients with chronic low back pain

Ejder BERK, Vedat NACITARHAN, Adnan DEMİREL, Bilgehan KOLUTEK AY

Retrospective analysis of inpatients in a recently established palliative care center

Burhan DOST, Hilmi BOZKURT

Single center 10 years’ experience of acute lymphoblastic leukemia in childhood: Retrospective cohort study

Gökhan AYTEKİN, Selma EROL AYTEKİN, Hüseyin TOKGÖZ, Ümran ÇALIŞKAN

Clinical characteristics of newborns with long bone fractures: A single center experience

Ali Erkan YENİGÜL, Nefise NAZLI YENİGÜL

A retrospective analysis of dental implants in patients who received a mandibular overdenture with locator attachment

Özge PARLAR OZ, Nermin DEMİRKOL

A rare cause of hypovolemic shock after cesarean delivery; Rectus sheath hematoma

Mehmet BÜLBÜL, Talip KARACOR, Mehmet Can NACAR, Memet ŞİMŞEK