Beyza ÖZCAN, Saime SÜNDÜS UYGUN, Murat KONAK, Hanifi SOYLU, Ahmet SERT

Evaluation of the results of pulse oximetry screening for detection congenital heart disease in Konya region, Turkey; Is it cost effective?

Aim: Congenital heart disease (CHD) is one of the most common congenital anomalies. It is known that early detection of the criticallesions without symtomatic improves the prognosis of patients in the long term. In our study, we aimed to evaluate the efficacy andcost of pulse oximetry screening for detection of CHD in Konya region.Material and Methods: In our study, we analyzed the results of pulse oximetry screening of infants born between 2016 and 2018in Selcuk University and Saglik Bilimleri University Konya Training and Research Hospital. Positive screening test results and theircosts was evaluated.Results: Pulse oximetry was performed on a total of 3440 infants for screening congenital heart disease at two different centers. 2003(58.2%) of the cases were female and 1437 (41.8%) were male. The mean timing of screening was 24.7±13.1 (4-100) hours (mean ±SD (min-max). 292 (8.48%) infants were tested positive. Echocardiographic examination was performed in the positive cases. Theprevalence of CHD was found to be 27.6 ‰. The prevalence of critical CHD was 1.16 per 1000 live births. The false-positive screenrate was found to be 197 (5.7%). Among the cases who were screened, the most common CHD was the secundum ASD. The totalcost of probes was 2622 ₺ ($497.91). The cost of echocardiography for 292 babies was approximately 13181 ₺ ($2503).Conclusion: Screening for heart disease can be used effectively in the early diagnosis of serious and life-threatening diseasesin newborn and the cost is unneglectable in the early screening of patients. This study, the total cost of each infant screening isapproximately 4.5 ₺ ($0.85) which appears to be a quite cheap and effective screening compared to the other countries.

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