Comparison of major appendicitis scoring systems on the clinical-histopathological correlation

Comparison of major appendicitis scoring systems on the clinical-histopathological correlation

Aim: We aimed to investigate the predictive value of the four most popular scoring systems, such as Modified Alvarado, Raja Isteri Pengiran Anak Saleha Appendicitis, Tzanakis, and Lintula, for histopathologically proven acute, phlegmonous, and gangrenous/perforated appendicitis. Materials and Methods: We retrospectively reviewed the results of 239 patients who underwent appendectomy between 2016 and 2019 in our department. The patients' demographic data, surgery method, histopathological results of the specimens (uncomplicated acute appendicitis, phlegmonous, and gangrenous/perforated appendicitis) were recorded. The predictivity of Modified Alvarado, Raja Isteri Pengiran Anak Saleha Appendicitis, Tzanakis, and Lintula scoring systems according to the histopathological results was compared.Results: The modified Alvarado scoring system showed statistically significant efficacy in the preoperative distinction of acute, phlegmonous, and gangrenous/perforated appendicitis. Although the Raja Isteri Pengiran Anak Saleha Appendicitis and Tzanakis score systems are effective in acute and gangrenous/perforated differentiation, they did not show statistically significant efficacy between acute and phlegmonous appendicitis. The Lintula scoring system was the weakest among the four and did not show statistically significant efficacy in the distinction of all three diagnoses. Conclusion: The diagnosis of acute appendicitis is easier with the use of scoring systems. Scoring systems can also help signal advanced stage and complicated forms of acute appendicitis, such as phlegmonous and gangrenous/perforated appendicitis. The modified Alvarado was the most correlated scoring system with histopathological results.

___

  • 1. Bhangu A, Søreide K, Di Saverio S, et al. Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. Lancet 2015;386:1278- 87.
  • 2. Kabir SA, Kabir SI, Sun R, et al. How to diagnose an acutely inflamed appendix; a systematic review of the latest evidence. Int J Surg 2017;40:155-62.
  • 3. Atema JJ, van Rossem CC, Leeuwenburgh MM, et al. Scoring system to distinguish uncomplicated from complicated acute appendicitis. Br J Surg 2015;102:979-90.
  • 4. Wagner M, Tubre DJ, Asensio JA. Evolution and current trends in the management of acute appendicitis. Surg Clin North Am 2018;98:1005-23.
  • 5. Tekeli MT, Ilhan E, Ureyen O, et al. How much reliable is Alvarado Scoring System in reducing negative appendectomy? Indian J Surg 2017;79:106-10.
  • 6. Isik A, Demiryilmaz I, Yilmaz I, et al. Effectiveness of Manual Knotting at Laparoscopic Appendectomy. Gazi Medical J 2016;27:19-20
  • 7. Kalan M, Talbot D, Cunliffe WJ, et al. Evaluation of the modified Alvarado score in the diagnosis of acute appendicitis:a prospective study. Ann R Coll Surg Engl 1994;76:418-9.
  • 8. Chong CF, Adi MIV, Thien A, et al. Evaluation of the RIPASA score:A new scoring system for the diagnosis of acute appendicitis. Singapore Med J 2010;51:220- 5.
  • 9. Walczak DA, Pawełczak D, Żółtaszek A, et al. The value of scoring systems for the diagnosis of acute appendicitis. Pol Przegl Chir 2015;87:65-70.
  • 10. van Amstel P, Gorter RR, van der Lee JH, et al. Ruling out appendicitis in children: Can we use clinical prediction rules? J Gastrointest Surg 2019;23:2027-48.
  • 11. Perez KS, Allen SR. Complicated appendicitis and considerations for interval appendectomy. JAAPA 2018;31:35-41.
  • 12. Young KA, Neuhaus NM, Fluck M, et al. Outcomes of complicated appendicitis: Is conservative management as smooth as it seems? Am J Surg 2018;215:586-92.
  • 13. Li Z, Zhao L, Cheng Y, et al. Abdominal drainage to prevent intra-peritoneal abscess after open appendectomy for complicated appendicitis. Cochrane Database Syst Rev 2018;5:CD010168.
  • 14. Chong CF, Thien A, Mackie AJ, et al. Comparison of RIPASA and Alvarado scores for the diagnosis of acute appendicitis. Singapore Med J 2011;52:340-5.
  • 15. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med 1986;15:557-64.
  • 16. Lintula H, Pesonen E, Kokki H, et al. A diagnostic score for children with suspected appendicitis. Langenbecks Arch Surg 2005;390:164-70.
  • 17. Ojuka D, Sangoro M. Alvarado vs Lintula Scoring Systems in Acute Appendicitis. Ann Afr Surg 2017;14:22-8.
  • 18. Lakshminarasimhaiah AKS, Nagaraja AL, Srinivasaiah M. Evaluation of Tzanakis scoring system in acute appendicitis: a prospective study. IntSurg J 2017;4:3338-43.
  • 19. Mán E, Simonka Z, Varga A, et al. Impact of the Alvarado score on the diagnosis of acute appendicitis: comparing clinical judgment, Alvarado score, and a new modified score in suspected appendicitis: a prospective, randomized clinical trial. Surg Endosc 2014;28:2398-405.
  • 20. Kamran H, Naveed D, Asad S, et al. Evaluation of modified Alvarado score for frequency of negative appendicectomies. J Ayub Med Coll Abbottabad 2010;22:46-9.
  • 21. Akbar I, Shehzad JA, Ali S. Diagnostic accuracy of the Ripasa Score. J Ayub Med Coll Abbottabad 2019;31:411-14.
  • 22. Lintula H, Kokki H, Pulkkinen J, et al. Diagnostic score in acute appendicitis. Validation of a diagnostic score (Lintula score) for adults with suspected appendicitis. Langenbecks Arch Surg 2010;395:495-500.
  • 23. Erdem H, Cetinkunar S, Das K, et al. Alvarado, Eskelinen, Ohhmann and Raja Isteri Pengiran Anak Saleha Appendicitis scores for diagnosis of acute appendicitis. World J Gastroenterol 2013;19:9057-62.
  • 24. Deiters A, Drozd A, Parikh P, et al. Use of the Alvarado score in elderly patients with complicated and uncomplicated appendicitis. Am Surg 2019;85:397- 402.
  • 25. Avanesov M, Wiese NJ, Karul M, et al. Diagnostic prediction of complicated appendicitis by combined clinical and radiological appendicitis severity index (APSI). Eur Radiol 2018;28:3601-10.
  • 26. Chan J, Fan KS, Mak TLA, et al. Pre-Operative Imaging can Reduce Negative Appendectomy Rate in Acute Appendicitis. Ulster Med J. 2020;89:25-8.
  • 27. Mariadason JG, Wang WN, Wallack MK, et al. Negative appendicectomy rate as a quality metric in the management of appendicitis: impact of computed tomography, Alvarado score and the definition of negative appendicectomy. Ann R Coll Surg Engl 2012;94:395-401.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi