A case of pediatric infratentorial oligodendroglioma
A case of pediatric infratentorial oligodendroglioma
Pediatric posterior fossa tumors most commonly are pilocytic astrocytomas (PA), ependymomas, medulloblastomas, and atypical teratoid rhabdoid tumor (ATRT). MRI has some special radiological findings which can be used in the differential diagnosis. We report on the radiologic images and the clinical course of a 3 year-old-girl with oligodendroglial tumor arising from the cerebellum. There were no focal deficits in the neurological examination. MRI revealed a left cerebellar lesion extending into the left cerebellopontine region causing a pressure and shift in the fourth ventricle, pons and mesencephalon. She underwent a left occipital craniectomy and total tumor decompression. In the pathological examination, mainly oligodendroglial cells were seen in the tumor and they had round nucleus and perinuclear halos. No recurrence was detected at MRI and CT at 6 months postoperatively. Except for the following most common tumors as PA, ependymoma, medulloblastoma and AT/RT in the posterior fossa, the oligodendroglioma must be considered in the differential diagnosis.
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- 1. Legler JM, Gloeckler Ries LA, Smith MA, et al Brain and other central nervous sys- tem cancers: recent trends in incidence and mortality. J Natl Cancer Inst 1999;91:1382-90.
- 2. Gold E. Epidemiology of brain tumors. Rev Cancer Epidemiol 1982;1:245.
- 3. Rumboldt Z, Camacho DL, Lake D, et al. Apparent diffusion coefficients for differentiation of cerebellar tumors in children. AJNR Am J Neuroradiol 2006;27:1362-9.
- 4. Meyers SP, Kemp SS, Tarr RW. MR imaging features of medulloblastomas. AJR Am J Roentgenol 1992;158:859-65.
- 5. Rorke LB, Packer RJ, Biegel JA, Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood. definition of an entity. J Neurosurg 1996;85:56-65.
- 6. Hendrik W, Mack Stephen C, Ryzhova M, et al. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 2011;20:143-57.
- 7. Ouni EF, Gaha M, Moulahi H, et al. Infratentorial oligodendroglioma in a child: a case report and review of the literature. Turkish Neurosurg 2012;22:461-4.
- 8. Smits M. Imaging of oligodendroglioma. Br J Radiol 2016;89:20150857.