Mehmet Eray ALÇIĞIR, Arda Selin TUNÇ, Sevil VURAL ATALAY, H. Kaan MÜŞTAK

Bir tavşanda doğal Pasteurella multocida enfeksiyonu: patolojik ve mikrobiyolojik bulgular

Olguda 4,5 yaşlı dişi bir tavşanda karşılaşılan generalize pasteurellozis patomorfolojik ve mikrobiyolojik olarak tanımlanmıştır. Makroskopik olarak tavşanın sağ boyun bölgesinde 6x4x3 cm boyutlarında fluktuan kıvamlı, kesit yüzünden koyu kıvamda beyazımsı renkte sıvı sızan bir kitle fark edildi. Akciğerlerde özellikle apikal loblarda hepatize alanlar, karaciğerde toplu iğne başı büyüklüğünde beyaz renkli odaklar dikkati çekti. Boyunda karşılaşılan kitlenin subkutanöz apse olduğu gözlendi. Ayrıca akciğerde akut kataral bronkopnömoni, fokal plöritis, karaciğerde multifokal nekrotik hepatitis ve beyinde fokal akut ensefalitis ile karşılaşıldı. Örneklerden bakteriyolojik izolasyon konvansiyonel mikrobiyolojik metotlar ile yapıldı. İzolatlar fenotipik özelliklerine göre P.multocida olarak identifiye edildi. Ayrıca izolatların moleküler konfirmasyonu P.multocida plpE genine spesifik polimeraz zincir reaksiyonu (PZR) ile gerçekleştirildi.

Naturally infection with Pasteurella multocida in a rabbit: the pathological and microbiological findings

In the case, it was described the generalized pasteurellosis in a 4,5-year-old female rabbit as pathomorphological and microbiological. Macroscopically, a mass which was 6x4x3 cm in diameter, fluctuant and pus like white color and crema leaking from the cross-section, was attended in right side of neck. On lungs especially in apical lobes, hepatized areas and at the liver, white colored spots was taken into attention. The mass encountered in the neck was subcutaneous abscess. In addition, acute catarrhal bronchopneumonia on the lungs, focal pleuritis, multifocal necrotic hepatitis at the liver and focal acute encephalitis at the brain were encountered. Bacterial isolation from samples were done by using conventional microbiologic methods. Isolates were identified as P.multocida according to phenotypic features. Also, molecular confirmation of isolates were carried out by polymerase chain reaction (PCR) which was spesific to plpE gene of P.multocida.

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