The relationship between health-related quality of life and demographic characteristics in patients with chronic hepatitis B

The relationship between health-related quality of life and demographic characteristics in patients with chronic hepatitis B

Introduction: The evaluation of health-related quality of life at specific intervals in chronic hepatitis B patients is important in terms of producing interventions aimed at raising quality of life. Aim: The purpose of this study was to measure health-related quality of life in CHB patients and to evaluate its association with demographic characteristics. Material and Method: The study was conducted with CHB patients presenting to the infectious diseases clinic between 01 January and 15 March, 2020. Date were collected demographic characteristics, and with the short form-36 (SF-36). Results: Two hundred fourteen patients diagnosed with CHB and receiving nucleos(t)ide therapy were included in the study. Patients’ mean age was 41.9±12.9 years, 60.7% (n=130) were men, 83.6% were married, and 44.9% were educated to middle school level. Mean scores on all subscales were higher among men. Patients’ SF-36 subscale scores differed significantly in terms of education. Unmarried individuals registered higher mean scales on the SF-36 subscales compared to married participants. The score distributions of housewives and clerical workers differed significantly on the physical functioning (PF), social functioning (SF), and physical role limitation (PRL) subscales (p

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  • EASL. European Association for the Study of the Liver.Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol 2017; 67: 370-98.
  • Sarin SK, Kumar M, Lau GK, et al. Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update. Hepatol Int 2016; 10: 1-98.
  • Terrault NA, Bzowej NH, Chang K-M, Hwang JP, Jonas MM, Murad MH. AASLD guidelines for treatment of chronic hepatitis B. Hepatology (Baltimore, Md) 2016; 63: 261.
  • Cai S, Yu T, Jiang Y, Zhang Y, Lv F, Peng J. Comparison of entecavir monotherapy and de novo lamivudine and adefovir combination therapy in HBeAg-positive chronic hepatitis B with high viral load: 48-week result. Clin Exp Med 2016; 16: 429-36.
  • CDC. Center for Disease Control and Prevention. HRQOL Concepts. Why is quality of life of important?April 01, 2016 2016 [Available from: http://www.cdc.gov/hrqol/concept.htm. updated: Accessed 26 February 2020.
  • Karacaer Z, Cakir B, Erdem H, et al. Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey. Health Qual Life Outcomes 2016; 14: 153.
  • Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med Care 1992: 473-83.
  • Pınar R. A new concept in health research: quality of life, testing the validity and reliability of a quality of life scale in chronic patients. Nurs Bull 1995; 9: 85-95.
  • Kocyigit H. Reliability and validity of the Turkish version of short form-36 (SF-36): a study in a group of patients will rheumatic diseases. Turk J Drugs Ther 1999; 12: 102-6.
  • Pradhan RR, Kafle Bhandari B, Pathak R, et al. The Assessment of Health-Related Quality of Life in Patients With Chronic Liver Disease: A Single-Center Study. Cureus 2020; 12: e10727.
  • Xue X, Cai S, Ou H, Zheng C, Wu X. Health-related quality of life in patients with chronic hepatitis B during antiviral treatment and off-treatment. Patient Prefer Adherence 2017; 11: 85-93.
  • Fotos NV, Elefsiniotis I, Patelarou A, et al. Psychological Disorders and Quality of Life Among Patients With Chronic Viral Hepatitis: A Single-Center Cross-Sectional Study With Pair-Matched Healthy Controls. Gastroenterol Nurs 2018; 41: 206-18.
  • Li L, Mo F, Hui EP, et al. The association of liver function and quality of life of patients with liver cancer. BMC Gastroenterol 2019; 19: 66.
  • Li G, Wang G, Hsu FC, et al. Effects of Depression, anxiety, stigma, and disclosure on health-related quality of life among chronic hepatitis b patients in Dalian, China. Am J Trop Med Hyg 2020; 102: 988-94.
  • Zhong C, Yin J, Zheng Z, Cai S, Gao Y. Risk factors associated with fatigue in chronic hepatitis B patients. Patient Prefer Adherence 2019; 13: 1065-72.
  • Varì R, Scazzocchio B, D'Amore A, Giovannini C, Gessani S, Masella R. Gender-related differences in lifestyle may affect health status. Ann Ist Super Sanita 2016; 52: 158-66.
  • Monin JK. Commentary on “Low Mood and Risk of Dementia: The Role of Marital Status and Living Situation”. Am J Geriatr Psychiatry. 2020; 28: 45-7.
  • Bulloch AGM, Williams JVA, Lavorato DH, Patten SB. The depression and marital status relationship is modified by both age and gender. J Affect Disord 2017; 223: 65-8.
  • Taşbakan MI, Sertöz ÖÖ, Pullukçu H, Çalik Ş, Sipahi OR, Yamazhan T. Comparison of quality of life in hepatitis B virus carriers versus chronic hepatitis B virus carriers versus the normal population. Turk J Med Sci 2010; 40: 575-83.
  • Özkan M, Çorapçioglu A, Balcioglu I, et al. Psychiatric morbidity and its effect on the quality of life of patients with chronic hepatitis B and hepatitis C. Int J Psychiatr Med 2006; 36: 283-97.
  • Lam ET, Lam CL, Lai C, Yuen M, Fong DY, So TM. Health-related quality of life of Southern Chinese with chronic hepatitis B infection. Health Qual Life Outcomes 2009; 7: 52.
  • Alay H, Özden K, Serpil E, Celik N, Parlak E, Parlak M. Assessment of Quality of Life of Patients with Chronic Hepatitis B and C Treated with Pegylated Interferon-alpha. Viral Hepatitis J 2018; 24: 25.
Anatolian Current Medical Journal-Cover
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2019
  • Yayıncı: MediHealth Academy Yayıncılık
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