Green Synthesis of Gold Nanoparticles Using Pomegranate Peel Extract and Its Antioxidant and Anticancer Activity against Liver Cancer Cell Line

Decrease of gold metal particles in contact with the watery strip concentrate of pomegranate organic product finishes the bio-union of gold nanoparticles. At the frequency scope of 350-700nm, an assimilation pinnacle of the biosynthesized gold nanoparticles is noticed. At 530nm, the UV-Visible range of gold nanoparticles orchestrated by pomegranate strip remove shows most extreme pinnacle assimilation. SEM has contemplated the morphological qualities of gold nanoparticles, affirming the round type of gold nanoparticles and their size of around 16nm. The essential investigation of gold nanoparticles blended by pomegranate strip remove has a gold level of 59.90 percent by weight. The gold nanoparticles combined by pomegranate strip extricate showed high cell reinforcement action. The examination shows that orchestrated gold nanoparticles exhibit conceivable anticancer action to build the grouping of gold nanoparticles against the HepG-2 liver malignant growth cell line.

___

Vairavel, M., Devaraj, E., and Shanmugam, R., 2020. An ecofriendly synthesis of Enterococcus sp.–mediated gold nanoparticle induces cytotoxicity in human colorectal cancer cells. Environmental Science and Pollution Research, 27(8): 8166–8175. https://doi.org/10.1007/s11356-019-07511-x

Menon, S., Agarwal, H., Rajeshkumar, S., Rosy, P.J., and Shanmugam, V.K., 2020. Investigating the antimicrobial activities of the biosynthesized selenium nanoparticles and its statistical analysis. Bio Nano Science: 1-14. https://doi.org/10.1007/s12668-019-00710-3

Kanniah, P., Radhamani, J., Chelliah, P., Muthusamy, N., Joshua Jebasingh Sathiya Balasingh Thangapandi, E., Reeta Thangapandi, J., and Shanmugam, R., 2020. Green Synthesis of Multifaceted Silver Nanoparticles Using the Flower Extract of Aerva lanata and Evaluation of Its Biological and Environmental Applications. Chemistry Select, 5(7): 2322-2331. https://doi.org/10.1002/slct.201903228.

Raj, R.K., Ezhilarasan, D., and Rajeshkumar, S., 2020. β-Sitosterol-assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line. Journal of Biomedical Materials Research: 1–10. https://doi.org/10.1002/jbm.a.36953.

Ganapathy, D., Shanmugam, R., and Sekar, D., 2020. Current status of nanoparticles loaded medication in the management of diabetic retinopathy. Journal of Evolution of Medical and Dental Sciences, 9(22): 1713-1718. https://doi.org/10.14260/jemds/2020/376

Rajakumari, R., Volova, T., Oluwafemi, O.S., Rajesh Kumar, S., Thomas, S., and Kalarikkal, N., 2020. Grape seed extract-soluplus dispersion and its antioxidant activity. Drug Development and Industrial Pharmacy, 46(8): 1219-1229. https://doi.org/10.1080/03639045.2020.1788059.

Nandhini, J.T., Ezhilarasan, D., and Rajeshkumar, S., 2020. An ecofriendly synthesized gold nanoparticles induces cytotoxicity via apoptosis in HepG2 cells. Environmental Toxicology: 1–9. https://doi.org/10.1002/tox.23007.

Vikneshan, M., Saravanakumar, R., Mangaiyarkarasi, R., Rajeshkumar, S., Samuel, S.R., Suganya, M., and Baskar, G., 2020. Algal biomass as a source for novel oral nano-antimicrobial agent. Saudi Journal of Biological Sciences, 2020. https://doi.org/10.1016/j.sjbs.2020.08.022.

Wu, S., Rajeshkumar, S., Madasamy, M., and Mahendran, V., 2020. Green synthesis of copper nanoparticles using Cissus vitiginea and its antioxidant and antibacterial activity against urinary tract infection pathogens. Artificial Cells, Nanomedicine, and Biotechnology, 48(1): 1153-1158. https://doi.org/10.1080/21691401.2020.1817053.

El-Desouky, T.A., Sherif, M.R., Sherif, M.S., and Khayria, N.M., 2015. Protective effect of aqueous extract pomegranate peel against sterigmatocystin toxicity in rat. Journal of Drug Delivery and Therapeutics, 5(5): 9-18.

Negi, P.S., Jayaprakasha, G.K., and Jena, B.S., 2003. Antioxidant and antimutagenic activities of pomegranate peel extracts. Food chemistry, 80(3): 393-397.

Middha, S.K., Usha, T., and Pande, V., 2013. A review on antihyperglycemic and antihepatoprotective activity of eco-friendly Punica granatum peel waste. Evidence-Based Complementary and Alternative Medicine: 1-10.

Rajeshkumar, S., 2017. Antioxidant activity of characterized silver nanoparticles synthesized using flower extracts of Chrysanthemum indicum. Research Journal of Biotechnology, 12(8): 38-43.

Rajeshkumar, S., 2016. Anticancer activity of eco-friendly gold nanoparticles against lung and liver cancer cells. Journal of Genetic Engineering and Biotechnology, 14(1): 195-202.

Shankar, S.S., Ahmad, A., and Sastry, M., 2003. Geranium leaf assisted biosynthesis of silver nanoparticles. Biotechnology progress, 19(6): 1627-1631.

Aromal, S.A., and Philip, D., 2012. Green synthesis of gold nanoparticles using Trigonella foenum-graecum and its size-dependent catalytic activity. Spectrochimica acta Part A: molecular and biomolecular spectroscopy, 97: 1-5.

Abdelhalim, M.A.K., Mady, M.M., and Ghannam, M.M., 2012. Physical properties of different gold nanoparticles: ultraviolet-visible and fluorescence measurements. Journal of Nanomedicine & Nanotechnology, 3(3): 178-194.

Blagoi, Y.P., Galkin, V.L., Gladchenko, G.O., Kornilova, S.V., Sorokin, V.A., and Shkorbatov, A.G., 1991. Metal complexes of nucleic acids in solutions. Naukova Dymka, Kiev (in Russian), 272.

Paulkumar, K., Rajeshkumar, S., Gnanajobitha, G., Vanaja, M., Malarkodi, C., and Annadurai, G., 2013. Ecofriendly synthesis of silver chloride nanoparticles using Klebsiellaplanticola (MTCC 2277). International journal of Green chemistry and Bioprocess, 3(1): 12-16.

Kaur, AD., Nain, P., and Nain, J., 2012. In-vitro Antimicrobial and Antioxidant Activity of GinkdoBiloba Bark Extract. International Research Journal of Pharmacy, 3(6): 116-119.

Rajeshkumar, S., Kumar, S.V., Ramaiah, A., Agarwal, H., Lakshmi, T., and Roopan, S.M., 2018. Biosynthesis of zinc oxide nanoparticles usingMangiferaindica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells. Enzyme and microbial technology, 117: 91-95.

Dhinesh, B., Bharathi, R.N., Lalvani, J.I.J., Parthasarathy, M., and Annamalai, K., 2017. An experimental analysis on the influence of fuel borne additives on the single cylinder diesel engine powered by Cymbopogonflexuosus biofuel. Journal of the Energy Institute, 90(4): 634-645.

Devi, V.S., and Gnanavel, B.K., 2014. Properties of concrete manufactured using steel slag. Procedia Engineering, 97(12): 95-104.

Sahu, D., Kannan, G.M., and Vijayaraghavan, R., 2014. Carbon black particle exhibits size dependent toxicity in human monocytes. International journal of inflammation, 2014.

Vijayakumar, G.N.S., Devashankar, S., Rathnakumari, M., and Sureshkumar, P., 2010. Synthesis of electrospunZnO/CuOnanocompositefibers and their dielectric and non-linear optic studies. Journal of alloys and compounds, 507(1): 225-229.

Mohan, M., and Jagannathan, N., 2014. Oral field cancerization: an update on current concepts. Oncology Reviews, 8(1): 244.

Lekha, L., Raja, K.K., Rajagopal, G., and Easwaramoorthy, D., 2014. Synthesis, spectroscopic characterization and antibacterial studies of lanthanide (III) Schiff base complexes containing N, O donor atoms. Journal of Molecular Structure, 1056: 307-313.

Panda, S., Doraiswamy, J., Malaiappan, S., Varghese, S.S., and Del Fabbro, M., 2016. Additive effect of autologous platelet concentrates in treatment of intrabony defects: a systematic review and meta‐analysis. Journal of investigative and clinical dentistry, 7(1): 13-26.

Putchala, M.C., Ramani, P., Sherlin, H.J., Premkumar, P., and Natesan, A., 2013. Ascorbic acid and its prooxidant activity as a therapy for tumours of oral cavity–a systematic review. Archives of oral biology, 58(6): 563-574.

Danda, A.K., 2010. Comparison of a single noncompressionminiplate versus 2 noncompressionminiplates in the treatment of mandibular angle fractures: a prospective, randomized clinical trial. Journal of oral and maxillofacial surgery, 68(7): 1565-1567.

Kavitha, M., Subramanian, R., Narayanan, R., and Udhayabanu, V., 2014. Solution combustion synthesis and characterization of strontium substituted hydroxyapatite nanocrystals. Powder technology, 253: 129-137.

Venu, H., Subramani, L., and Raju, V.D., 2019. Emission reduction in a DI diesel engine using exhaust gas recirculation (EGR) of palm biodiesel blended with TiO2 nano additives. Renewable energy, 140: 245-263.

Neelakantan, P., Varughese, A.A., Sharma, S., Subbarao, C.V., Zehnder, M., and De‐Deus, G., 2012. Continuous chelation irrigation improves the adhesion of epoxy resin‐based root canal sealer to root dentine. International endodontic journal, 45(12): 1097-1102.

Gopalakannan, S., Senthilvelan, T., and Ranganathan, S., 2012. Modeling and optimization of EDM process parameters on machining of Al 7075-B4C MMC using RSM. Procedia Engineering, 38: 685-690.

Venu, H., Raju, V.D., and Subramani, L., 2019. Combined effect of influence of nano additives, combustion chamber geometry and injection timing in a DI diesel engine fuelled with ternary (diesel-biodiesel-ethanol) blends. Energy, 174: 386-406.

Lekha, L., Raja, K.K., Rajagopal, G., and Easwaramoorthy, D., 2014. Schiff base complexes of rare earth metal ions: Synthesis, characterization and catalytic activity for the oxidation of aniline and substituted anilines. Journal of Organometallic Chemistry, 753: 72-80.

Krishnamurthy, A., Sherlin, H.J., Ramalingam, K., Natesan, A., Premkumar, P., Ramani, P., and Chandrasekar, T., 2009. Glandular odontogenic cyst: report of two cases and review of literature. Head and neck pathology, 3(2): 153-158.

Parthasarathy, M., Lalvani, J.I.J., Dhinesh, B., and Annamalai, K., 2016. Effect of hydrogen on ethanol– biodiesel blend on performance and emission characteristics of a direct injection diesel engine. Ecotoxicology and environmental safety, 134: 433-439.

Pradeep Kumar, A.R., Shemesh, H., Jothilatha, S., Vijayabharathi, R., Jayalakshmi, S., and Kishen, A., 2016. Diagnosis of vertical root fractures in restored endodontically treated teeth: a time-dependent retrospective cohort study. Journal of Endodontics, 42(8): 1175-1180.

Neelakantan, P., Grotra, D., and Sharma, S., 2013. Retreatability of 2 Mineral Trioxide Aggregate–based Root Canal Sealers: A Cone-beam Computed Tomography Analysis. Journal of endodontics, 39(7): 893-896.

Sajan, D., Lakshmi, K.U., Erdogdu, Y., and Joe, I.H., 2011. Molecular structure and vibrational spectra of 2, 6-bis (benzylidene) cyclohexanone: A density functional theoretical study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 78(1): 113-121.

Uthrakumar, R., Vesta, C., Raj, C.J., Krishnan, S., and Das, S.J., 2010. Bulk crystal growth and characterization of non-linear optical bisthiourea zinc chloride single crystal by unidirectional growth method. Current Applied Physics, 10(2): 548-552.

Neelakantan, P., Cheng, C.Q., Mohanraj, R., Sriraman, P., Subbarao, C., and Sharma, S., 2015. Antibiofilm activity of three irrigation protocols activated by ultrasonic, diode laser or Er: YAG laser in vitro. International endodontic journal, 48(6): 602-610.

Neelakantan, P., Sharma, S., Shemesh, H., and Wesselink, P.R., 2015. Influence of irrigation sequence on the adhesion of root canal sealers to dentin: a Fourier transform infrared spectroscopy and push-out bond strength analysis. Journal of endodontics, 41(7): 1108-1111.

Prathibha, K.M., Johnson, P., Ganesh, M., and Subhashini, A.S., 2013. Evaluation of salivary profile among adult type 2 diabetes mellitus patients in South India. Journal of clinical and diagnostic research: JCDR, 7(8): 1592-1595.
Alınteri Zirai Bilimler Dergisi-Cover
  • ISSN: 2564-7814
  • Başlangıç: 2007
  • Yayıncı: Adem Yavuz SÖNMEZ
Sayıdaki Diğer Makaleler

Operational Image Processing Approach for Spray Coverage Measurements in Pesticide Application

Bahadır SAYINCI, Ruçhan ÇÖMLEK, Mustafa ÇOMAKLI, Bünyamin DEMİR

First Report on Marine Actinobacterial Diversity around Madras Atomic Power Station (MAPS), India

P. SİVAPERUMAL, S. RAJESHKUMAR, T. LAKSHMİ

Forecasting of Long-term Sugar Beet Water Requirement in the Middle Anatolia, Turkey

Sevim Seda YAMAÇ

Seroepidemiological and Clinicopathological Study of Feline Coronavirus (FCoV) and Feline Infectious Peritonitis (FIP), Could Guide to SARS-CoV-2 (COVID-19) in ‘One Health’ Approach

Bilge Kaan TEKELİOGLU

Assessment of Allelopathic Prospective of Agriculture Land Trees on Morphological and Yield Attributes of Wheat Varieties of Pakistan

Iqra JALALİ, Abbas Hussain SHAH, Muhammad FAROOQ, Tabinda JABEEN, Khalid Rasheed KHAN, Laiba ZOHRA

New Approach in Obtaining the Ideal Watermelon (Citrullus lanatus) Seedling: Tebuconazole

HÜSEYİN BULUT, Halil İbrahim ÖZTÜRK

Capabilities to Use Plants Grown in Wetlands of Erzurum for Landscape Design

Hilal TURGUT, Sevgi YILMAZ

Determination of the Yield Quality and Winter Durability Characteristics of Some Bread Wheat (Triticum aestivum) Genotypes in Pasinler and Erzincan Locations

Halit KARAGÖZ, Ümran KÜÇÜKÖZDEMİR, Berrin DUMLU, Zeki YALÇIN

Effect of IFAD-VCDP on Input-Output Commercialization of Rice Farmers in Niger State of Nigeria

M. SADIQ, I. SINGH

Different Doses of UV-B Treatments Increase Total Soluble Phenols and Anthocyanin Content of Eregli Black Carrot (Daucus carota L. spp. sativus var. atrorubens Alef.) During Storage

Mehmet Feridun AZTEKİN, REZZAN KASIM, M. Ufuk KASIM