İftikhar AHMAD, Zain Ul ABIDIN, Aisha KHATOON

Distribution of Serotypes of Foot and Mouth Disease Virus Among Different Outbreaks Occurring in Punjab Province, Pakistan (2001-2010)

ABSTRACTFoot and mouth disease virus (FMDV) comes under genus Aphthovirus and family Picornaviridae and it causes a severe vesicular disease in cloven footed animals especially cattle. It has seven different serotypes but only four of them (O, A, Asia I, C) are prevalent in Pakistan. The present study was aimed to evaluate the prevalence of these serotypes in Punjab province, Pakistan. A total of 659 samples were collected from different outbreaks of FMD occurring in Punjab province from 2001 to 2010. The samples were analysed by complement fixation test by using commercially available hyper immune sera of 4 serotypes. Results showed that 234 samples were positive for FMDV out of which 178 (27.01%) samples were positive for O, 4 (0.60%) for A, 48 (7.28%) for Asia I and 4 (0.60%) for C from 659 number of samplesKey Words: Foot and mouth disease virus, foot and mouth disease, hyper immune serum, complement fixation test ÖZETPAKİSTAN, PENCAP İLİNDE ORTAYA ÇIKAN FARKLI SALGINLARDA ŞAP HASTALIĞI VİRÜSÜNÜN SEROTİPLERİNİN DAĞILIMI (2001-2010)Şap hastalığı virüsü Aphthovirus cinsi ve Picornaviridae ailesine ait olup, başta sığır olmak üzere çift tırnaklı hayvanlarda önemli veziküler hastalığın oluşumuna neden olmaktadır. Yedi farklı serotipi olmasına rağmen bunlardan sadece dördü (O, A, Asya I, C) Pakistan'da yaygındır. Bu çalışmada, Pakistan'da Pencap ilinde bu serotiplerin prevalansının belirlemesi amaçlanmıştır. 2001 ile 2010 yılları arasında Pencap ilinde meydana gelen farklı şap hastalığı salgınlarından toplam 659 örnek toplanmıştır. Örnekler, ticari olarak temin edilen 4 serotipe ait hiper immun serumlar kullanılarak, komplement fiksasyon testi ile incelendi. Sonuçlar 659 örneğin 234'ünin şap hastalığı virüsü yönünden pozitif olduğunu, 178'inin (%27,01) O serotipinde, 4'ünün (%0,60) A serotipinde, 48'inin (%7,28) Asya I serotipinde ve 4'ünün (%0,60) C serotipinde olduğunu göstermiştir.Anahtar Kelimeler: Şap hastalığı virüsü, şap hastalığı, hiper immun serum, komplement fiksasyon testi

Anahtar Kelimeler:

Şap hastalığı virüsü, şap hastalığı, hiper immun serum, komplement fiksasyon testi

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Foot and mouth disease virus (FMDV) comes under genus Aphthovirus and family Picornaviridae and it causes a severe vesicular disease in cloven footed animals especially cattle. It has seven different serotypes but only four of them (O, A, Asia I, C) are prevalent in Pakistan. The present study was aimed to evaluate the prevalence of these serotypes in Punjab province, Pakistan. A total of 659 samples were collected from different outbreaks of FMD occurring in Punjab province from 2001 to 2010. The samples were analysed by complement fixation test by using commercially available hyper immune sera of 4 serotypes. Results showed that 234 samples were positive for FMDV out of which 178 (27.01%) samples were positive for O, 4 (0.60%) for A, 48 (7.28%) for Asia I and 4 (0.60%) for C from 659 number of samples

Keywords:

Foot and mouth disease virus, foot and mouth disease, hyper immune serum, complement fixation test,

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