Introduction: The aim of this study is to examine the patient characteristics, locations, presentations and histopathological features of pilomatrixomas in a group of patients. Methods: We analyzed 41 patients that histopathologically diagnosed as pilomatrixoma in Erzurum Regional Training and Research Hospital between 2009 ad 2014, retrospectively. Results: Patients mean age was 30 years (age range: 378 years), with a female to male ratio of 26: 15. There were 12 patients in the pediatric age group (<16 years). The average diameter of the lesion at presentation was 18.5 mm (range: 255 mm). A total of 36 out of 41 (87.8%) patients presented with solitary lesion, while 5 patient (12.2%) had two lesions. Most common location in our patient group was head and neck region and second most common location was limbs. The most common clinical presentation was a painless solitary skin lesion which was noticed incidentally. All cases more or less shared the same microscopic features of pilomatrixoma such as basophilic cells, eosinophilic shadow cells, calcification and foreign body type giant cells. Conclusion: Pilomatrixoma is not an uncommon benign lesion. It is more common in female gender, adult age group and at the head and neck region.
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