Kronik Sigara çicili¤inin P Dalga Süresi ve Dispersiyonu Üzerine Etkisi
Bu çalflmada; 30 a¤r sigara içicisi, 30 hafif sigara içicisi ve sigara içicisi olmayan 30 olguda P dalga süresi ve dispersiyonu (PWD) ölçülmüfltür. A¤r sigara içicisi, hafif sigara içicisi ve sigara içicisi olmayan olgu gruplarnda ölçülen maksimum p dalga süresi ve PWD srasyla (117±9ms, 116±8ms, 115±6ms ANOVA p=0.78 ve 48±10ms, 45±11ms, 43±8ms, one-way ANOVA p=0.14) olarak bulundu, anlaml fakllk izlenmedi. Ayrca olgu gruplarnda ölçülen minimum P dalga süresi de benzer bulunmufltur (69±10ms, 70±13ms, 72±9ms, one-way ANOVA p=0.51). Bununla birlikte sigara içim süresi, içilen sigara says ve P dalga süresi arasnda doz ba¤ml iliflki bulunmamfltr. Sa¤lkl genç yafllardaki olgularda tek baflna kronik sigara içimi, P dalga süresi ve PWD üzerinde de¤ifliklik oluflturmamaktad r.
Effect of Habitual Cigarette Smoking on P Wave Duration and Dispersion
In this study, P wave duration and dispersion (PWD) were measured in 30 heavy smoker, 30 light smoker and 30 nonsmoker subjects. There were no significant difference among heavy smokers, light smokers and nonsmokers with respect to maximum P wave duration and PWD (117±9ms, 116±8ms, 115±6ms ANOVA p=0.78, and 48±10ms, 45±11ms, 43±8ms, one-way ANOVA p=0.14, respectively). Minimum P wave duration was also similar in three groups. (69±10 ms, 70±13ms, 72±9ms, one-way ANOVA p=0.51). We also found no dose dependent-relation between the duration of smoking, the number of cigarettes smoked, and P wave duration. Habitual cigarette smoking alone does not alter P wave duration and PWD in otherwise healthy young subjects.
___
- Hallstrom AP, Cobb LA, Ray R Smoking as a risk factor for recurrence of sudden cardiac arrest. N Eng J Med 1986; :271-5
- Peters RW, Brooks MM, Todd L, Liebson PR, Wilhelmsen L Smoking cessation and arrhythmic death: the CAST experien- ce. J Am Coll Cardiol 1995; 26: 1287-92
- Waters D, Lesperance J, Gladstone P, Effect of cigarette smoking on the angiographic evalution of coronary atherosc- lerosis: A Canadian coronary atherosclerosis intervention trial (CCAIT) substudy. Circulation 1996; 94: 614-21
- Cryer PE, Haymond MW, Santiago JV, Shah SD Norepinep- hrine release and adrenergic mediation of smoking-associa- ted hemodynamic and metabolic events. N Eng J Med 1976; :573-7
- Hill P, Wynder EL Smoking and cardiovascular disease:ef- fect of nicotine on the serum epinephrine and corticoids. Am Heart J 1974; 87: 491-6
- LaCroix AZ, Omenn GS Older adults and smoking. Clin Ge- riatr Med 1972; 8: 69-87
- Lakier JB Smoking and cardiovascular disease. Am J Med ; 93:8S-12S deBruyne MC, Hoes AW, Kors JA, Hofman A, van Bemmel JH, Grobbee DE QTc dispersion predicts cardiac mortality in the elderly: The Rotterdam Study. Criculation 1998; 97: 467-72
- Dilaveris P, Pantazis A, Gialafos E, Triposkiadis F, Gialafos J The effect of cigarette smoking on the heterogeneity of ven- tricular repolarization. Am Heart J 2001; 142:833-37
- Kofluyolu Kalp Dergisi Hekim Karapınar, MD Ileri M, Yetkin E, Tandogan I. Effect of habitual smoking on QT interval duration and dispersion. Am J Cardiol 2001; 88: 325
- Dilaveris PE, Gialafos EJ, Andrikopoulos GK, et al. Clinical and electrocardiographic predictors of recurrent atrial fibrilla- tion. Pacing Clin Electrophysiol 2000; 23:352-358
- Dilaveris PE, Gialofos JE P-wave dispersion: a novel pre- dictor of paroxysmal atrial fibrillation. Ann Noninvasive Elec- trocardiol 2001; 6: 159-165
- Cheema AN, Ahmed MW, Kadish AH, Goldberger JJ Ef- fects of autonomic stimulation and blockade on signal-avera- ged P wave duration. J Am Coll Cardiol 1990; 26: 497-502
- Leier CV, Meacham JA, Schall SF Prolonged atrial con- duction: A major predisposing factor to atrial flutter. Circulati- on 1978; 57: 213-216
- Tukek T, Akkaya V, Demirel S. Effect of valsalva maneuver on surface electrocardiographic P wave dispersion in paroxy- smal atrial fibrillation. Am J Cardiol 2000; 85: 896-899
- Dogan A, Acar G, Gedikli O, et al. A comparison of P-wa- ve duration and dispersion in patients with short-term and long-term atrial fibrllation. J Electrocardiol 2003; 36: 251-255
- Camsari A, Pekdemir H, Akkus N, Yenihan S, Doven O, Cin VG Long-term effects of beta blocker theraphy on P-wave du- ration and dispersion in congestive heart failure patients. A new effect? J Electrocardiol. 2003; 36: 111-116
- Kotamaki M Smoking induced differences in autonomic responses in military pilot candidates. Clin Auton Res 1995; 5: 36
- Lucini D, Bertocchi F, Malliani A, Pagani M A controlled study of the autonomic changes produced by habitual cigarette smoking in he- althy subjects. Cardiovasc Res 1996; 31: 633-6