Iron deficiency in Helicobacter pylori infected patients in Baghdad

Anahtar Kelimeler:

Iron deficiency, anemia, H.pylori

Iron deficiency in Helicobacter pylori infected patients in Baghdad

Objectives: Recent studies have suggested an association of Helicobacter pylori and iron deficiency (ID). Materials and methods: To examine an association between H.pylori infection and ID, blood sampling and a data collection survey were performed in 78 H.pylori infected patients and 22 healthy subjects as control. Serum ferritin and iron were measured by ELISA and direct enzymatic method techniques respectively. Results: The result showed that 24 of the patients (30.7%) have serum ferritin and iron concentrations below the normal range indicating iron deficiency, with no significantly difference between women and men. ID was more pronounced in patients with stomach ulcer (58.3%) than those without stomach ulcer (41.7%) respectively. Conclusions: The conclusion was that H.pylori infection might have a role in iron deficiency and subsequently iron deficiency anemia.

Kaynakça

Blaser M.J., Atherton J.C. Helicobacter pylori persistence: bi- ology and disease. J Clin Invest 2004; 113:321-333.

Lacy BE, Rosemore J. Helicobacter pylori: Ulcers and more: the beginning of an era. J Nutr 2001; 131:2789S–2793S.

Go MF. Review article: natural history and epidemiology of Helicobacter pylori infection. Aliment Pharmacol Ther 2002; 16 (Suppl 1): 3–15.

NIH Consensus Conference. NIH consensus development panel on Helicobacter pylori in peptic ulcer disease. JAMA 1994, 272: 65–69.

Parkinson AJ, Gold BD, Bulkow L et al. High prevalence of Helicobacter pylori in the Alaska native population and as- sociation with low serum ferritin levels in young adults. Clin Diagn Lab Immunol 2000; 7: 885–888.

Berg G, Bode G, Blettner M, Boeing H, Brenner H. Helico- bacter pylori infection and serum ferritin: A population-based study among 1806 adults in Germany. Am J Gastroenterol 2001; 96: 1014–1018.

Baggett HC, Parkinson AJ, Muth PT, Gold BD, Gessner BD. Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in Alaska. Pediatrics 2006; 117: e396–e404.

Cardenas VM, Mulla ZD, Ortiz M, Graham DY. Iron deficiency and Helicobacter pylori infection in the United States. Am J Epidemiol 2006; 163: 127–134.

Choe YH, Lee JE, Kim SK. Effect of Helicobacter pylori eradi- cation on sideropenic refractory anaemia in adolescent girls with Helicobacter pylori infection. Acta Paediatr 2000; 89: 154–157.

Choe YH, Kwon YS, Jung MK, Kang SK, Hwang TS, Hong YC. Helicobacter pylori-associated iron-deficiency anemia in adolescent female athletes. J Pediatr 2001; 139: 100-104.

Mahalanabis D, Islam MA, Shaikh S, et al. Haematological response to iron supplementation is reduced in children with asymptomatic Helicobacter pylori infection. Br J Nutr 2005; 94: 969–975.

Weyermann M, Rothenbacher D, Gayer L, et al. Role of Heli- cobacter pylori infection in iron deficiency during pregnancy. Am J Obstet Gynecol 2005; 192: 548–553.

Siekmann JH, Allen LH, Watnik MR, Nestel P, Neumann CG, Shoenfeld Y, Peter JB, Patnik M, Ansari AA, Coppel RL, Ger- shwin ME. Titers of antibody to common pathogens: relation to food-based interventions in rural Kenyan schoolchildren. Am J Clin Nutr. 2003, 77: 242–249.

Dubois S, Kearney DJ. Iron-deficiency anemia and Helico- bacter pylori infection: a review of the evidence. Am J Gas- troenterol 2005; 100:453–9.

Barabino A. Helicobacter pylori-related iron deficiency ane- mia: a review. Helicobacter 2002; 7:71–75.

Yip R, Limburg PJ, Ahlquist DA, et al. Pervasive occult gas- trointestinal bleeding in an Alaska native population with prevalent iron deficiency. Role of Helicobacter pylori gastritis. JAMA 1997; 277:1135–9.

Stoltzfus RJ. Iron deficiency: global prevalence and conse- quences. Food Nutr Bull; 2003, 24: S97–S101.

Baysoy G, Ertem D, Ademoglu E, et al. Gastric histopathol- ogy, iron status and iron deficiency anemia in children with Helicobacter pylori infection. J Pediatr Gastroenterol Nutr 2004; 38: 146-151.

Capurso G, Lahner E, Marcheggiano A, et al. Involvement of the corporal mucusa and related changes in gastric acid secretion characterize patients with iron deficiency anaemia associated with Helicobacter pylori infection. Aliment Phar- macol Ther 2001; 15: 1753–1761.

Yip R, Limburg PJ, Carpenter HA, et al. Pervasive occult gastrointestinal bleeding in an Alaska native population with prevalent iron deficiency. Role of Helicobacter pylori gastritis. JAMA 1997; 277:1135–1139.

Perez-Perez GI, Israel DA. Role of iron in Helicobacter pylori: its influence in outer membrane protein expression and in pathogenicity. Eur J Gastroenterol Hepatol 2000; 12: 1263- 1265.

Boggs, Well. Eradication of H.pylori reduces iron deficiency anemia prevalence. J Infect Dis 2009; 199:652-660.

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