Bu çalışmada, 11 'i leptospirozisli, 10'u leptospirozislen şüpheli, 10 tanesi ise sağlıklı olan 6-12 aylık sığırlar kullanıldı. Leptospirozisli hayvanların serum sialik asit ve lipid-bağlı sialik asit düzeylerinde leptospirozisten şüpheli ve kontrol hayvanlara kıyasla isîatistiki olarak önemli artışlar (p

In the present study, 11 cattle with leptospirosis, 10 cattle suspected with leptospirosis and 10 healthy cattle aged between 6-12 months were used. Serum sialic acid and lipid-bound sialic acid concentrations were found to be increased significantly (p<0.001) compared to the values obtained from control and leptospirosis suspected cattle. Increase in these values are thought to be direct effect of toxins on cell membranes released from leptospirae spp. Important changes in sialic acid and lipid-bound sialic acid concentration were not observed in the serum samples obtained from leptospirosis suspected animals. This is because etytrocyte membranes may not had been effected by the toxins.