Nihat Bahtiyar BAKIR, İSMAİL ALKAN, KAMİL SAĞLAM, FERDA BELGE, NİHAT ŞINDAK, Mehmet KARACA

Köpeklerde oluşturulan üçüncü derece termal yanıklarda, sağlatım amacıyla kullanılan antioksidan kan gazları ve bazı hematolojik parametreler

Bu çalışma değişik yaş ve cinsiyette 20 adet melez köpekte gerçekleştirildi. Hayvanlar l'i kontrol 3'ü (C vitamini, E vitamini ve pentoxijylline) deneme olmak üzere 5 'erli 4 gruba ayrıldı. Deneysel olarak göğüs çeperinde 16 cm çapında derin yanık oluşturuldu. Yanığı takiben 10 gün süreyle tüm gruplara gümüş sülfadiazine kremi sürülürken deneme gruplarına bu süre boyunca C grubuna Cvitamini im, E grubuna E vitamini im ve P grubuna da pentoxifylline peros uygulandı. Yanık öncesi ve sonrası 1, 3 ve 7. günlerde kan gazları ve hematolojik parametreler incelenerek sonuçlar değerlendirildi. Kan parametrelerinden lölcosit sayısı hariç önemli bir değişikliğe rastlanmazken kan gazlarında hem grup içi hem de gruplar arası istatistiki değerlendirmelerde anlamlı değişikliklere rastlanmıştır.

Anahtar Kelimeler:

askorbik asit, kan bileşimi, yanık, sülfadiazin, E vitamini, kan gazları, köpek, pentoksifilin

The effect of antioksidant agents,used for the treament of third degree thermal burns, on blood gases and some haematological parameters in dogs

This study was performed on 20 cross-breed dogs of in different age and sex. The dogs were divided into four groups of five. A deep 16 an in diameter burn was experimentally made up in all groups of animals. After burn, sülfadiazine cream was applied to all groups of animals for a 10 days period. Additionally, group C received vitamin-C im, group E received vitamini-E im and group P received pentoxijylline peros. Before and, 1, 3. and 7 days after burn, blood gases and haematological parameters were recorded and analysed. Haematological findings showed no significant changes except the number of leukocytes which was significantly increased. Furthermore, blood gases values were also significantly different between the control experimental groups and in between each experimental groups.

Keywords:

ascorbic acid, blood composition, burns, sulfadiazine, vitamin E, blood gases, dogs, pentoxifylline,

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