Extraperitoneal laparoskopik radikal prostatektomi: İlk 60 vaka deneyimi
Amaç: Bu çalışmada kliniğimizde laparoskopik radikal prostatektomi uygulanan ilk 60 hastanın öğrenme eğrisinin başındaki sonuçları retrospektif olarak değerlendirilmiştir.Gereç ve Yöntem: Ocak 2006 ve Haziran 2011 tarihleri arasında lokalize prostat kanseri tanısı alan 60 hastaya ekstraperitoneal desending laparoskopik radikal prostatektomi uygulandı. Hastaların peroperatif ve postoperatif bulguları değerlendirildi.Bulgular: Preoperatif PSA değeri ortalaması 8,8 ng /ml, gleason skoru 6, ortalama operasyon süresi 255 dk ve transfüzyon alan hasta %60 olarak tesbit edildi. Dört hastada açık operasyona dönüldü. Postoperatif erken dönemde 7 hastada komplikasyon görüldü. Hastaların ortalama hastanede kalış süresi 7 gün olarak gerçekleşti. 10 hastada uzun süreli kateterizasyon gerekti. Hastaların operasyon süresi transfüzyon oranı, kateterizasyon süresi, hastalığın onkolojik kontrolü, potens ve kontinans durumu değerlendirildi.Postoperatif dönemde 2 hastada kanama, 5 hastada hematomve 2 hastada skrotal ödem saptandı. 2 olguda anastomoz kaçağı nedeni ile sonda alınma süresi uzadı. Postoperatif anastomoz hattında darlık gelişen 2 hastada transüretral insizyon uygulandı.Bilateral sinir koruyucu cerrahi yapılan 22 hastanın 8 inde potensin geri geldiği izlendi. Postoperatif dönemde hastaların 44 ‘ünün PSA düzeyi
Laparoscopic extraperitoneal radical prostatectomy: Experience in first 60 patients
Objectives: In this study, the learning curve of the first 60 patients on whom laparoscopic radical prostatectomy was performed in our clinic was evaluated retrospectively.Materials and Methods: Between January 2006 and June 2011, a total of 60 patients have been diagnosed with localized prostate cancer underwent laparoscopic extraperitoneal descending radical prostatectomy in our clinic. Preoperative and postoperative results of these patients were evaluated.Results: The mean values of preoperative PSA and Gleason score were 8.8ng/ml and 6 respectively. The mean operation duration was 255 minutes, and the blood transfusion was needed in %60 of the patients. 4 patients were transitied to open surgery.Complications were occured at early postoperative period in 7 patients. The mean hospital stay was 7 days. 10 patients required long-term catheterization. Operation time, transfusion rate, length of catheterization, oncological outcomes, potency and continence status were evaluated. In the postoperative period, hemorrhagie was seen in 2 patients, haematoma 5 and scrotal edema in 2. In 2 cases, catheter duration was extended because of the anastomotic leakage. Transurethral incision was performed in 2 patients who developed postoperative anastomotic stricture. Potency was regained in 8 of the 22 patients who went through bilateral protective neurosurgery. In the postoperative period, PSA level was measured
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- Rassweiler J, Sentker L, Seeman O, Hatzınger M, Rumpelt HJ. Laparoscopıc radical prostatectomy with the Heilb- ronn Technique: An Analysis of the fırst 180 cases. J Urol 2001; 66: 2101-2108.
- Guilloneau B, Cathelineau X, Barret E, et al. Laparoscopic radical prostatectomy: technical and early oncological as- sesment of 40 operations. Eur Urol 1999; 36: 14.
- Bollens R, Vanden Bossche M, Roumeguere T, Damoun A, Ekane S, Hoffmann P, et al. Extraperitoneal laparosco- pic radical prostatectomy. Results after 50 cases. Eur Urol 2001; 40: 65.
- Salomon L, Sèbe P, De la Taille A, Vordos D, Hoznek A, Yiou R, Chopin D, Abbou CC. Open versus laparoscopic radical prostatectomy. Part II. BJU Int. 2004 Jul;94(2):244- 250.
- Schuessler WW, Shulam PG, Clayman RV, Kavoussi LR. Laparoscopic radical prostatectomy: initial short term ex- perience. Urology 1997; 50: 854-7.
- Guilloneau B, Cathelineau X, Barret E, Rozet F, Vallencien G. Laparoscopic radical prostatectomy. Preliminary evalu- ation after 28 interventions. Presse Med 1998; 27: 1570-4.
- Laparoscopic extraperitoneal radical prostatectomy: im- pact of the learning curve on perioperative outcomes and margin status. Rodriguez AR, Rachna K, Pow-Sang JM. JSLS. 2010 Jan-Mar;14(1):6-13.
- Guilloneau B and Vallencien G. Laparoscopic radical prostatectomy: the Montsouris experience. J Urol 2000; 163: 418.
- Perioperative complications of laparoscopic radical prosta- tectomy: the Montsouris 3-year experience.Guillonneau B, Rozet F, Cathelineau X, Lay F, Barret E, Doublet JD, Bau- mert H, Vallancien G. J Urol. 2002 Jan;167(1):51-6.
- Salomon L, Sèbe P, De la Taille A, Vordos D, Hoznek A, Yiou R, Chopin D, Abbou CC. Open versus laparoscopic radical prostatectomy: Part I. BJU Int .2004 Jul; 94(2): 238- 43
- Eden CG, Cahıll D, Vass JA, Adams TH, Dauleh MI. Lapa- roscopic radical prostatectomy: the initial UK series. BJU Int. 2002; 90: 876-882.
- Rozet F, Galiano M, Cathelineau X, Barret E, Cathala N, Vallancien G. Extraperitoneal laparoscopic radical prosta- tectomy: a prospective evaluation of 600 cases. J Urol 2005 Sep; 174(3): 908-11.
- Rassweiler J, Schulze M, Teber D, Seemann O, Frede T. La- paroscopıc radical prostatectomy: functional and oncolo- gical outcomes. Curr Opin Urol 2004 Mar; 14(2): 75-82.
- Salomon L, Levrel O, Anastasiadis AG, Saint F, de La Ta- ille A, Cicco A, Vordos D, Hoznek A, Chopin D, Abbou CC. Outcome and complications of radical prostatectomy in patients with PSA
- Secin FP, Savage C, Abbou C, de La Taille A, Salomon L, Rassweiler J, et al. The learning curve for laparoscopic ra- dical prostatectomy: an international multicenter study. J Urol. 2010 Dec; 184(6):2291-6.
- Oncologic outcome after extraperitoneal laparoscopic ra- dical prostatectomy: midterm follow-up of 1115 procedu- res. Paul A, Ploussard G, Nicolaiew N, Xylinas E, Gillion N, de la Taille A, Vordos D, Hoznek A, Yiou R, Abbou CC, Salomon L. Eur Urol. 2010 Feb;57(2):267-72. Epub 2009 Sep 17.
- Coelho RF, Rocco B, Patel MB, Orvieto MA, Chauhan S, Ficarra V, Melegari S, Palmer KJ, Patel VR. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a critical review of outcomes reported by high-volume cen- ters. J Endourol. 2010 Dec;24(12):2003-15.
- Mariano MB, Tefilli MV, Fonseca GN, Goldraich IH. La- paroscopic radical prostatectomy: 10 years experience. Int Braz J Urol. 2009 Sep-Oct;35(5):565-71
- Stolzenburg JU, Do M, Rabenalt R, Pfeiffer H, Horn L, Truss MC, Jonas U, Dorschner W. Endoscopic extraperito- neal radical prostatectomy: initial experience after 70 pro- cedures. J Urol 2003 Jun; 169(6): 2066-71
- Imamoto T, Goto Y, Utsumi T, Fuse M, Kawamura K, Ka- miya N, Naya Y, Suzuki H, Kondo Y, Ichikawa T. Complica- tions, urinary continence, and oncologic outcomes of lapa- roscopic radical prostatectomy: single-surgeon experience for the first 100 cases. Prostate Cancer. 2011;2011:606505