Böbrek hücreli kanserde yaş ve cinsiyetin sağkalım üzerine etkisi
Amaç: Radikal nefrektomi yapılan hastalarda yaş ve cinsiyetin sağ kalıma etkisini araştırmak. Gereç ve Yöntemler: 1990 – 2012 tarihleri arasında kliniğimizde böbrek tümörü nedeniyle radikal nefrektomi operasyonu uygulanan 177 hasta retrospektif olarak değerlendirildi. Hastalar yaş gruplarına göre 5 gruba
The effect of age and gender on survival in renal cell carcinoma
Objective: To evaluate the effect of age and gender on survival in patients who underwent radical nephrectomy. Materials and Methods: A hundred and seventy seven patients who underwent radical retrospectively because of renal carcinoma were eveluated retrosepectively between 1990 and 2012. Patients are divided into five groups
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- Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
- Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-81.
- Lindblad P. Epidemiology of renal cell carcinoma. Scand J Surg 2004;93:88-96.
- Ferlay J, Bray F, Forman D, et al. GLOBOCAN 2008 v1.2, Cancer Incidence and MortalityWorldwide: IARC Cancer- Base No. 10 2010, International Agency for Research on Cancer:Lyon,France.
- Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg classification of renal cell tumours. J Pathol 1997;183:131- 3.
- Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176:2353-8.
- Bergstrom A, Hsieh CC, Lindblad P, et al. Obesity and renal cell cancer-a quantitative review. Br J Cancer 2001;85:984- 90.
- Pischon T, Lahmann PH, Boeing H, et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition EPIC. Int J Cancer 2006;118:728-38
- Weikert S, Boeing H, Pischon T, et al. Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition. Am J Epidemiol 2008;167:438-46.
- Waalkes S, Merseburger AS, Kramer MW, et al. Obesity is associated with improved survival in patients with organ- confined clear-cell kidney cancer. Cancer Causes Control 2010;21:1905-10.
- Clague J, Lin J, Cassidy A, et al. Family history and risk of renal cell carcinoma: results from a case control study and systematic meta-analysis. Cancer Epidemiol Biomarkers Prev 2009;18:801-7.
- Gudbjartsson T, Jónasdóttir T.J, Thoroddsen A, et al. A population-based familial aggregation analysis indicates genetic contribution in a majority of renal cell carcinomas. Int J Cancer 2002;100:476-9.
- Patard JJ, Rodriguez A, Rioux-Leclercq N, et al. Prognos- tic significance of the mode of detection in renal tumours. BJU Int 2002;90:358-63.
- Kato M, Suzuki T, Suzuki Y, et al. Natural history of small renal cell carcinoma: evaluation of growth rate, histological grade, cell proliferation and apoptosis. J Urol 2004;172:863-6.
- Tsui KH, Shvarts O, Smith RB, et al. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urol 2000;163:426-30.
- Jung EJ, Lee HJ, Kwak C,et al. Young age is independent prognostic factor for cancer-specific survival of low-stage clear cell renal cell carcinoma. Urology 2009;73:137-41.
- Denzinger S, Otto W, Burger M,et al. Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?. World J Urol 2013;31:1073-80.
- Lee L.S, Yuen J.S.P, Sim H.G. Renal cell carcinoma in yo- ung patients is associated with poorer prognosis. Annals Academy of Medicine 2011;40:401-406.
- Thompson R.H, Ordonez M.A, Iasones A, et al. Renal cell carsinoma in young and old patient-is there a difference? Urologe A 2008;47:1182-1186.
- Karakiewicz P.T, Jeldres C, Suardi N, et al. Age at diag- nosis is determinant factor of renal cell carcinoma-spe- sific survival in patients treatedwith nephrectomy. J urol 2008;180:1262-1266.
- Sangchul J, Hwang G.J, Cheol K. et al. Gender-specific clinicopathological features and survival in patients with renal cell carcinoma RCC. BJU int 2011;110:28-33.
- Edward N. R, Tobias K, Geoffrey B. et al. The effect of gen- der and age on kidney cancer survival: Younger age is an indipendent prognostic factor in women with renal cell carcinoma. Urologic Oncology 2013;1-5.
- Schrader A.J, Sevinç S, Olbert P.J.et al. Gender specific cha- racteristics and survival of renal cell carcinoma. Urologe 2008;47:1182-1186.
- Onishi T, Oishi H, Goto H.et al. Gender as a prognostic factor in patients with renal cell carcinoma. BJU int 2002; 90:32-36.
- Aron M, Nguyen M.M, Stein R.J, et.al. Impact of gender in renal cell carcinoma: an analysis of the SEER database. Eur Urol jul 2008;54:13340.