Ahmet SEVİNDİK, Hakan NAZİK, RAZİYE NARİN, HAKAN AYTAN, Murat APİ

Gastasyonel Diyabetli Hastalarda İnsülin Tedavisi Gereksinmi ile İlişkili Faktörler

Amaç: Çalışmanın amacı gestasyonel diyabetli (GDM) hastalarda insülin tedavisi gereksinimiyle ilişkili faktörleri belirlemektir. Materyal ve Metot: Bu çalışma Ocak 2009Aralık 2010 yıllarında Adana Numune Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniğinde GDM tanısı ile yatırılarak tedavi edilen 40 hastanın retrospektif değerlendirilmesi ile yapılmıştır. Hastalar sadece diyet düzenlemesi ile glikoz regülasyonu sağlananlar (1. Grup) ve diyet + insülin tedavisi alanlar (2. Grup) olmak üzere iki gruba ayrıldı. Bu iki grup demografik özellikleri, 100 gr OGTT sonucu ve glikozillenmiş hemoglobin yüzdesi (HbA1c değerleri) yönünden karşılaştırıldı. Bulgular: Hastaların 22sinde (%55) sadece diyet düzenlemesi ile glikoz regülasyonu sağlanırken 18 hastada (%45) glikoz regülasyonu için diyet + insülin tedavisine gereksinim duyulmuştur. Demografik özelliklerden; yaşın ve vücut kitle indeksinin (VKø) 2. grupta anlamlı olarak daha yüksek olduğu bulunmuştur (p

(Factors associated with need for insulin treatment in patients with gestational diabetes)

Background: The aim of this study was to determine the factors associated with the need for insulin therapy in patients with gestational diyabetes (GDM). Material and Methods: This study is a retrospective study that was included 40 patients hospitalized with a diagnosis of GDM between January 2009 and December 2010 in Adana Numune Education and Research Hospital Clinic of Obstetrics and Gynecology. These patients were divided into two groups: only diet modification (Group 1) and diet + insulin therapy (Group 2). These two groups were compared in terms of demographic characteristics, 100 g OGTT results and the percentage of glycosylated hemoglobin (HbA1c) values. Results: According to the results of our study, regulation of glucose was achieved on 22 (55%) patients with only dietary modification and 18 patients (45%) received diet + insulin treatment for the regulation of glucose. From the demographic characteristics, age and body mass index (BMI) were found to be significantly higher in group 2 (p<0.05). Fasting plasma glucose (FPG) and HbA1c values were also found to be significantly higher in group 2 (p<0.001). There was no significant difference between the two groups compared in terms of birth weight. Conclusions: The need for insulin therapy was found to be increased in patients with a fasting plasma glucose level of 95mg/dl in 100 gr OGTT and serum HbA1c level of 5,6.

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