Effect of serum 25(OH) vitamin D On muscle strength and balance over 65 years of age: A cross sectional study
Amaç: Vitamin Dnin kırığa karşı koruyucu etkisi yanında, kas kuvvetini arttırarak düşmeleri azaltabileceği de bilinmektedir. Kesitsel çalışmalarda düşük serum 25 hidroksi vitamin D [25 (OH) D] seviyesinin kas kuvvetinde azalma, denge bozukluğu ve düşme riskinde artışla ilişkisi gösterilmiştir. Bu çalışmada, yaşlı popülasyonda, serum 25 (OH) D konsantrasyonu ile elin kavrama kuv- veti ve denge arasındaki ilişkinin araştırılması ve klinik pratikte kuvvetinin vitamin D eksikliğine bağlı gelişen kas kuvvetsizliği ve düşme riskinin anlaşılmasında el kavrama kuvvetinin kullanılıp kullanılamayacağını araştırmak üzere planlandı. Materyal ve Metot: Kesitsel olarak planlanan bu çalışmaya 65 yaş üstü, 53 katılımcı kabul edildi. Demografik özellikleri ve serum kalsiyum, fosfor, alkalen fosfataz (ALP), 25 OH D ve paratiroid hormon düzeylerini kapsayan laboratuar sonuçları değerlendirildi. Elin kavrama kuvveti, el dinamometresi ile, denge ise Berg Denge Skalası ile değerlendirildi. Bulgular: 25 (OH) D düzeylerine göre 20 ng/mLnin altında ve üstünde olarak iki gruba ayrılan katılımcıların el kavrama kuvvetleri ve Berg denge skalasının total skorları karşılaştırıldı. Berg denge skalası total skoru, 25 (OH) D düzeyi 20 ng/mL altında olan grupta diğer gruba göre istatistiksel olarak anlamlı derecede yüksek olarak saptandı (r:0,627, p=0,000). Ayrıca, 25 (OH) D düzeyi 20 ng/mLnin üstünde olan hastaların kavrama kuvvetleri daha yüksek bulundu (p=0,023 and p=0,037, sırası ile dominant ve non-dominant eller için). Sonuçlar: Bu çalışma Vitamin Dnin kas kuvveti, fonksiyonu ve denge üzerine önemli etkileri olduğunu desteklemektedir. Geriatri popülasyonunda vitamin D eksikliğinin tedavisi kas kuvveti ve dengeyi düzelterek düşmelere de engel olacaktır.
Serum 25(OH) vitamin D düzeyinin kas kuvveti ve denge üzerine etkisi: 65 yaş üzeri popülasyonda kesitsel bir çalışma
Background: Vitamin D has protective effect on fractures and improves muscle strength. Cross sectional studies have shown that low serum concentration of 25 hydroxy vitamin D[25 (OH) D] is related to decreased muscle strength, balance disorders and increased risk of falls. The purpose of this study was to assess the correlation between serum 25 (OH) D concentrations, grip strength and balance in older population to determine if grip strength could be used in clinical practice to estimate the risk of falls and muscle weakness secondary to vitamin D insufficiency. Materials and Methods: Fifty three participants over 65 years of age were enrolled. Demographics and laboratory results including serum calcium, phosphorous, alkaline phosphatase, 25 (OH) vitamin D and parathyroid hormone concentrations were assessed. Hand grip strength was measured by a hand dynamometer. Berg balance scale was used for the assessment of balance. Results: Grip strength and total score of Berg balance scale of participants with 25 (OH) vitamin D levels <20 ng/mL versus ≥20ng/mL were compared. Berg balance scale scores of patients with 25 (OH) D<20 ng/mL were higher than the other group (r:0.627, p=0.000). Participants with 25 (OH) D vitamin level of ≥20 ng/mL had higher grip strength compared to the other group (p=0.023 and p=0.037 for dominant and non-dominant hand respectively). Conclusions: Vitamin D is essential for muscle strength and balance and therefore treatment of vitamin D deficiency reduce the incidence of falls in older population by improving muscle strength and balance.
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