Koyunların Deneysel Ruminal Asidozisinin Farklı Safhalarında Klinik Bulgular, Rumen İçeriği, Hematolojik ve Biyokimyasal Parametrelerin Araştırılması

Bu araştırmada 12 g/kg ve 18 g/kg glikoz ile oluşturulan ruminal asidozisin farklı safhalarındaki klinik ve laboratuvar bulguların araştırılması amaçlanmıştır. Çalışmanın materyalini 2-3 yaşlarda, 51-62 kg canlı ağırlığında 12 adet sağlıklı koç oluşturdu. Koçlar iki gruba ayrıldı. 1. gruptakilere 12 g/kg CA, ikinci gruptakilere ise 18 g/kg CA dozunda glikoz oral yolla verilerek ruminal asidozis oluşturuldu. Ruminal asidozisli hayvanlarda iştahsızlık, diş gıcırdatma, inleme ve yumuşak kıvamlı dışkı veya ishalin şekillendiği gözlendi. Vücut ısısı ve nabız sayısının arttığı, solunum sayısının etkilenmediği, rumen hareketleri sayısının ise azaldığı saptandı. 1. grupta hematokrit değer (sadece 15. saatte) ile total lökosit sayısında artış (p

Anahtar Kelimeler:

Koyun, Deneysel, Ruminal asidozis, Glikoz, Klinik, Hematolojik, Biyokimyasal

Investigation of Hematological and Biochemical Parameters, Clinical Findings and Rumen Content in The Different Phases of Experimental Ruminal Acidosis in Sheep

The aim of this study was to investigate clinical and laboratory findings of 12 g/kg and 18 g/kg of glucoseinduced different phases of experimental ruminal acidosis. The materials of the study were consisted 12 healthy rams ages between 2-3 and 51-62 kg of weight. Rams were divided into two groups. In the first group of 12 g/kg BW and the second 18 g/kg BW glucose were given orally for created ruminal acidosis. Loss of appetite, teeth grinding, groaning and forming a soft consistency stool or diarrhea were observed in acidotic sheep. Increased body temperature and pulse frequency, respiratory frequency, were not changed while rumen movements decreased. In the first group hematocrit value (only in 15 hours) and total white blood cell count were increased (p<0.05) meanwhile erythrocyte count, hematocrit value, hemoglobin concentration and total white blood cell count were increased significantly (p<0.05) in second group. Although in the both groups serum Na and Cl concentrations increased (p<0.05) while the concentration of K was found to decreased (p<0.05). Decreased were detected occurred in pH of rumen contents and statistical differences were determined when compared between two groups in 6., 9., 24., 32., 48. and 72. hours (respectively p<0.01, p<0.05, p<0.01, p<0.05, p<0.01, p<0.05). As while the rate of acetate were increased, propionate and butyrate rations decreased. In addition to increasing of glucose dose affects the rate of acetate (respectively in 2., 6. and 12. hours p<0.01, p<0.01, p<0.05) and propionate rations (in 2., 6. and 48. hours respectively p<0.01, p<0.01, p<0.05) but for butyrate (p>0.05) did not affected. As a result, evaluation of clinical and laboratory findings in ruminal acidotic animals those finding must be consideration for determination of prognosis and treatment planning was concluded

Keywords:

Sheep, Experimental, Ruminal acidosis, Glucose, Clinical, Hematological, Biochemical,

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