The effects of isofluran on cardiac performance in dogs with experimental acute hemorrhagic anemia (AHA) were inves-tigated. A local anesthetic agent was administered to dogs in the control group (=2) and isofluran to dogs in the experimental group (n=6). Left ventricle systolic and diastolic blood pressure with filling and ejection time before and 15 min after AHA were deter-mined in all dogs. While left ventricle systolic blood pressure decreased (from 114±3 mm/Hg to 54±4 mm/Hg) and diastolic blood pressure decreased (from 88±6 mm/Hg to 40±2 mm/Hg), filling time increased (from 0.16±0.025 mm/sec to 0.40±0.065 mm/sec, p

The effects of isofluran on cardiac performance in dogs with experimental acute hemorrhagic anemia (AHA) were inves-tigated. A local anesthetic agent was administered to dogs in the control group (=2) and isofluran to dogs in the experimental group (n=6). Left ventricle systolic and diastolic blood pressure with filling and ejection time before and 15 min after AHA were deter-mined in all dogs. While left ventricle systolic blood pressure decreased (from 114±3 mm/Hg to 54±4 mm/Hg) and diastolic blood pressure decreased (from 88±6 mm/Hg to 40±2 mm/Hg), filling time increased (from 0.16±0.025 mm/sec to 0.40±0.065 mm/sec, p