Effect of Unilateral Adrenalectomy on the Blood Biochemistry of Black Bengal Goats (Capra hircus)

The present study was conducted to study the influence of unilateral adrenalectomy in the black Bengal goat and to observe its influence on stress alleviation capability in terms of changes in blood chemistry, and further emphasis was given to determine whether a single gland is sufficient for survival in these animals. Six female kids were unilaterally adrenalectomised and the other 6 were maintained as intact controls. Blood samples were drawn at regular intervals before and after surgery. Parameters included in the study were blood pH, blood volume, TEC, haemoglobin, PCV, TLC, differential leukocyte count, cortisol, glucose, total cholesterol, total protein, urea, and blood urea nitrogen. All the parameters were estimated by standard methods. All the blood biochemical parameters in the present study showed significant differences (P < 0.01) when compared to intact control animals. There was a significant increase in total plasma protein, total plasma cholesterol, blood urea, and blood urea nitrogen, and a significant decrease in plasma glucose and cortisol. The present study indicated that acute changes occurred in the blood biochemical parameters on unilateral adrenalectomy of the left adrenal gland that were later compensated for by the other intact right adrenal gland.

Effect of Unilateral Adrenalectomy on the Blood Biochemistry of Black Bengal Goats (Capra hircus)

The present study was conducted to study the influence of unilateral adrenalectomy in the black Bengal goat and to observe its influence on stress alleviation capability in terms of changes in blood chemistry, and further emphasis was given to determine whether a single gland is sufficient for survival in these animals. Six female kids were unilaterally adrenalectomised and the other 6 were maintained as intact controls. Blood samples were drawn at regular intervals before and after surgery. Parameters included in the study were blood pH, blood volume, TEC, haemoglobin, PCV, TLC, differential leukocyte count, cortisol, glucose, total cholesterol, total protein, urea, and blood urea nitrogen. All the parameters were estimated by standard methods. All the blood biochemical parameters in the present study showed significant differences (P < 0.01) when compared to intact control animals. There was a significant increase in total plasma protein, total plasma cholesterol, blood urea, and blood urea nitrogen, and a significant decrease in plasma glucose and cortisol. The present study indicated that acute changes occurred in the blood biochemical parameters on unilateral adrenalectomy of the left adrenal gland that were later compensated for by the other intact right adrenal gland.

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  • Khosa, S.L., Pachauri, S.P., Singh, R.P.: Effect of exogenous corticoids on haematological changes in dogs. Indian J. Vet. Med., 1983; 7: 85-89.
  • Hamelink, C.R., Currie, P.J., Chambers, J.W., Castonguay, T.W., Coscina, D.V.: Corticosterone-responsive and unresponsive metabolic characteristics of adrenalectomized rats. Am. J. Physiol., 1994; 267: 799-804.
  • Breazile, J.E.: Textbook of Veterinary Physiology. Lea & Febiger, Philadelphia. 1971.
  • Reece, W.O.: Fluid volume changes associated with withdrawal and restoration of steroid therapy in adrenalectomized dogs. Am. J. Vet. Res., 1972; 33: 1493-1498.
  • Courtice, F.C.: The blood volume of normal animals. J. Physiol., 1943; 102: 290-305.
  • Sen, M.M., Mia, A.S., Rahman, A.: Intravascular fluid volume of black Bengal goat. Bangladesh Vet. J., 2005; 9: 1-4.
  • Estergreen, V.L. Jr., Van Demark, N.L.: Some blood changes following bilateral adrenalectomy in the bull calf. J. Dairy Sci., 1959; 42: 926-931.
  • Estergreen, V.L. Jr., Van Demark, N.L.: Adrenalectomy of the calf and its effects on various blood constituents. J. Dairy Sci., 1961; 44: 928-936.
  • McDonald, L.E., Pineda, M.H.: Veterinary Endocrinology and Reproduction. 4thedn., Lea and Febiger, Philadelphia. 1989.
  • Hall, S.J.G., Broom, D.M., Kiddy, G.N.S.: Effect of transportation on plasma cortisol and packed cell volume in different genotypes of sheep. Small Ruminant Res., 1998; 29: 233-237.
  • Turner, A.I., Canny, B.J., Hobbs, R.J., Bond, J.D., Clarke, I.J., Tilbrook, A.J.: Influence of sex and gonadal status of sheep on cortisol secretion in response to ACTH and on cortisol and LH secretion in response to stress: importance of different stressors. J. Endocrinol., 2002; 173: 113-122.
  • Hamada, H., Seina, Y., Namikawa, K.: The role of glucocorticoids in the regulation of plasma glucose, insulin and glycogen in sheep. Jpn. J. Zootech. Sci., 1987; 58: 1011-1016.
  • Fujita, S., Donovan, C.M.: Celiac-superior mesenteric not ganglionectomy, sympathoadrenal response to insulin-induced hypoglycemia. Diabetes, 2005; 54: 3258-3264. suppresses the
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
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