Aggressive osteoblastoma of the cervical vertebrae in a Turkish Angora cat

  Aggressive osteoblastoma is a type of bone tumor rarely reported in veterinary literature. Osteoblastoma may be misdiagnosed as an osteosarcoma, which is a well-understood malignant bone tumor. Owing to poor prognosis, animals diagnosed with osteosarcoma are not always treated. In the present case, we diagnosed the tumor as aggressive osteoblastoma on the basis of macroscopic, microscopic, radiographic, and immunohistologic findings. The patient was treated via resections of the osteoblastoma and lived without metastasis for 3 years. This is the first reported case of aggressive feline osteoblastoma of the cervical vertebrae and will be useful for diagnosing and managing aggressive osteoblastoma.

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  • Berry M, Mankin H, Gebhardt M, Rosenberg A, Hornicek F. Osteoblastoma: a 30-year study of 99 cases. J Surg Oncol 2008; 98: 179-83.
  • Goedegebuure SA, Firth EC, Dik, KJ. Osteoblastoma in the radius of a pony. Vet Pathol 1983; 20: 650.
  • Benoit-Biancamano MO, D’Anjou, MA, Girard C, Langlois I. Rib osteoblastic osteosarcoma in an African hedgehog ( Atelerix albiventris ). J Vet Diagn Invest 2006; 18: 415.
  • Rosado KE, Pitt MJ, Siegal GP, Biology C. Osteoblastoma: a mimic of osteosarcoma. Pediatr Pathol Mol Med 2000; 19: 305-322.
  • Ye J, Liu L, Wu J, Wang S. Osteoblastoma of the rib with CT and MR imaging: a case report and literature review. World J Surg Oncol 2012; 10: 49.
  • Combalia Aleu A, Popescu D, Pomes J, Palacin A. Long- standing pain in a 25-year-old patient with a non-diagnosed cervical osteoblastoma. a case report. Arch Orthop Trauma Surg 2008; 128: 567-571.
  • El-Badawi ZH, Muhammad EMS, Noaman HH. Role of immunohistochemical cyclo-oxygenase-2 (COX-2) and osteocalcin in differentiating between osteoblastomas and osteosarcomas. Malays J Pathol 2012; 34: 15-23.
  • Hermann G, Klein M, Springfield D, Abdelwahab I. Osteoblastoma like osteosarcoma. Clin Radiol 2004; 59: 105-108.
  • Bertoni F, Unni KK, McLeod RA, Dahlin DC. Osteosarcoma resembling osteoblastoma. Cancer 1985; 55: 416-426.
  • Kan P, Schmidt MH. Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am 2008; 19: 65-70.
  • Samdani A, Torre-Healy A, Chou D, Cahill AM, Storm PB. Treatment of osteoblastoma at C7: a multidisciplinary approach. A case report and review of the literature. Eur Spine J 2009; 18: 196-200.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK