Anti-ulcerogenic activity of Ferulago isaurica and F. syriaca growing in turkey

Ferulago türlerinin halk arasındaki kullanımını değerlendirmek üzere, Ferulago isaurica Peşmen ve F. syriaca Boiss.’in (Apiaceae) toprak üstü kısımları ve köklerinden ayrı ayrı hazırlanan liyofilize sulu ekstrelerin antiülserojenik etkisi sıçanlarda EtOH ile oluşturulan ülser modeli ile çalışılmıştır. Tüm ekstreler uygulanan modele karşı istatistiksel olarak belirgin bir gastroprotektif aktivite gösterirken, en yüksek aktivite F. isaurica köklerinde görülmüştür (%100).

Türkiye'de yetişen Ferulago isaurica ve F. syriaca türlerinin antiülserojenik aktivitesi

In order to evaluate the claimed folkloric utilisation of Ferulago species, the anti-ulcerogenic activities of lyophilised aqueous extracts obtained from the aerial parts and roots of Ferulago isaurica Peşmen and F. syriaca Boiss. (Apiaceae) have been studied using EtOH-induced ulcerogenesis model in rats. All plant parts exhibited statistically significant gastroprotective activity against in vivo model employed in the present study however the highest activity was observed for the roots of F. isaurica (100%).

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