Background. Vogt-Koyanagi-Harada Syndrome is rare in childhood and is usually seen between the 2nd and 5th decades. We present a 15-year-old girl with findings of incomplete Vogt-Koyanagi-Harada Syndrome. Case. In the first visit, anterior chamber inflammation, vitritis, serous retinal detachment and papillitis were observed in her both eyes. She also had neurological symptoms such as a headache. During the systemic treatment period, some of the side effects related to steroids emerged. Additionally, the symptoms and findings of the disease relapsed while the steroid dose was reduced. Conclusion. Early diagnosis and selection of an individualized appropriate treatment provided good clinical and visual results without any serious complications in our case.
___
1. Yoshida A, Tominaga S, Kawashima H. Juvenile Vogt-Koyanagi-Harada disease in which good visual prognosis was derived from swift definitive diagnosis. Case Rep Ophthalmol Med 2016; 2016: 7936729.
2. Abu El-Asrar AM, Al-Kharashi AS, Aldibhi H, AlFraykh H, Kangave D. Vogt-Koyanagi-Harada disease in children. Eye (Lond) 2008; 22: 1124-1131.
3. Tabbara KF, Chavis PS, Freeman WR. VogtKoyanagi-Harada syndrome in children compared to adults. Acta Ophthalmol Scand 1998; 76: 723-726.
4. AlQahtani DS, Al Shamrani M. Case report of a 4-year-old child with complicated Vogt-KoyanagiHarada at a tertiary eye hospital. Middle East Afr J Ophthalmol 2019; 26: 117-119.
5. Katsuyama A, Kusuhara S, Awano H, Nagase H, Matsumiya W, Nakamura M. A case of probable Vogt-Koyanagi-Harada disease in a 3-year-old girl. BMC Ophthalmol 2019; 19: 179.
6. Khan F, Zahid S, Raza SS, Iqbal M. A case of Vogt Koyanagi Harada disease in a 16 year old girl. J Pak Med Assoc 2017; 67: 1759-1761.
7. Takada S, Tanaka R, Kurita N, Ishii K, Kaburaki T. Vogt-Koyanagi-Harada disease in 3-year-old boy. Clin Exp Ophthalmol 2015; 43: 593-594.
8. Bilgiç Ö, Gündüz A, Kaya K. Vogt-Koyanagi-Harada disease in an adolescent boy. Pediatr Dermatol 2014; 31: 99-101.
9. Vergaro R, Cordelli DM, Miniaci A, et al. Cerebral ischemic involvement in Vogt-Koyanagi-Harada disease. Pediatr Neurol 2014; 51: 119-122.
10. Bušányová B, Tomčíková D, Gerinec A. VogtKoyanagi-Harada syndrome in children - a case report. Cesk Slov Oftalmol 2013; 69: 81-86.
11. Hernandez C, LePoole C, Tessler HH. VogtKoyanagi-Harada syndrome in a 6-year-old Hispanic boy. Pediatr Dermatol 2012; 29: 191-194.
12. Venaille A, Palombi K, Templier I, et al. VogtKoyanagi-Harada syndrome: a serious and rare emergency in children. Arch Pediatr 2011; 18: 33-36.
13. Benfdil N, Baha Ali T, Jellab B, Moutaouakil A. Vogt Koyanagi Harada syndrome in children: diagnosis and management. Bull Soc Belge Ophtalmol 2010; 15-18.
14. Martin TD, Rathinam SR, Cunningham ET Jr. Prevalence, clinical characteristics, and causes of vision loss in children with Vogt-Koyanagi-Harada disease in South India. Retina 2010; 30: 1113-1121.
15. Damico FM, Kiss S, Young LH. Vogt-KoyanagiHarada disease. Semin Ophthalmol 2005; 20: 183- 190.
16. Pivetti-Pezzi P. Uveitis in children. Eur J Ophthalmol 1996; 6: 293-298.
17. Cunningham ET Jr, Kilmartin D, Agarwal M, Zierhut M. Sympathetic ophthalmia. Ocul Immunol Inflamm 2017; 25: 149-151.
18. Kumar A, Ghose A, Biswas J, Majumder PD. Clinical profile of patients with posterior scleritis: a report from Eastern India. Indian J Ophthalmol 2018; 66: 1109-1112.
19. Valmaggia C, Helbig H, Fretz C. Uveal effusion syndrome. Klin Monbl Augenheilkd 2007; 224: 317- 319.
20. Read RW, Holland GN, Rao NA, et al. Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature. Am J Ophthalmol 2001; 131: 647-652.
21. O’Keefe GA, Rao NA. Vogt-Koyanagi-Harada disease. Surv Ophthalmol 2017; 62: 1-25.
22. Lodhi SA, Reddy JL, Peram V. Clinical spectrum and management options in Vogt-Koyanagi-Harada disease. Clin Ophthalmol 2017; 11: 1399-1406.
23. Citterio-Quentin A, Moulsma M, Gustin MP, Lachaux A, Boulieu R. ITPA activity in children treated by azathioprine: relationship to the occurrence of adverse drug reactions and inflammatory response. Basic Clin Pharmacol Toxicol 2018; 122: 588-595.
24. Berker N, Ozdamar Y, Soykan E, Ozdal P, Ozkan SS. Vogt-Koyanagi-Harada syndrome in children: report of a case and review of the literature. Ocul Immunol Inflamm 2007; 15: 351-357.
25. Kim SJ, Yu HG. The use of low-dose azathioprine in patients with Vogt-Koyanagi-Harada disease. Ocul Immunol Inflamm 2007; 15: 381-387.
26. Cunningham ET Jr, Rathinam SR, Tugal-Tutkun I, Muccioli C, Zierhut M. Vogt-Koyanagi-Harada disease. Ocul Immunol Inflamm 2014; 22: 249-252