Ülkem KOÇOĞLU BARLAS, Hasan Serdar KIHTIR, Osman YEŞİLBAŞ, Mey Talip PETMEZCİ, Nihal AKÇAY, Ercüment PETMEZCİ, Nevin HATİPOĞLU, Esra ŞEVKETOĞLU

Tetanus; a forgotten infection disease: a report of two cases

Background. Tetanus is an infectious disease that can be seen in all age groups in underdeveloped and developing countries, where vaccination programs are inadequate. In developed countries, it is reported more frequently in the adult age group, where the protection of vaccination is diminished and the doses are delayed. Case. In this report, we present generalized tetanus, which was observed in two male patients aged 12 and 6 years, admitted at different times, together with clinical course and treatment approaches. Both patients belong to different nationalities, who immigrated a couple of months before their application to our hospital. They applied with similar histories and complaints and were not vaccinated during infancy. Conclusion. With the development of vaccination programs, this disease with high morbidity and mortality can be prevented.

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1. Stock I. Tetanus and clostridium tetani-a brief review. Med Monatsschr Pharm 2015; 38: 57-60.

2. Yalcın I, Salman N, Somer A. Bakteri enfeksiyonları. İçinde: Neyzi O, Ertuğrul T (eds). Pediatri Cilt 1-2 (4. Baskı), Ankara: Nobel Tıp Kitabevi, 2010: 613-616.

3. Aydın TT, Bayhan GI, Afsarlar CE, Oz FN, Akansel AR, Tanir G. A report of two pediatric tetanus cases. Turk J Pediatr 2011; 53: 437-440.

4. Tetanus vaccines: WHO position paper-February 2017. Wkly Epidemiol Rec 2017; 92: 53-76.

5. Rodrigo C, Fernando D, Rajapakse S. Pharmacological management of tetanus: an evidence based review. Crit Care 2014; 18: 217.

6. American Academy of Pediatrics. Tetanus (Lockjaw). In: Pickering LK, Baker CJ, Kimberlin DW, Long SS (eds). Red Book: 2012 Report of the Committee on Infectious Diseases (29th ed). Elk GroveVillage, IL: American Academy of Pediatrics, 2012: 707-712.

7. Kabura L, Ilibagiza D, Menten J, Van den Ende J. Intrathecal vs. intramuscular administration of human antitetanus immunoglobulin or equine tetanus antitoxin in the treatment of tetanus: a metaanalysis. Trop Med Int Health 2006; 11: 1075-1081.

8. McTague A, Martland T, Appleton R. Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children. Cochrane Database Syst Rew 2008; CD001905.

9. Burns J, Jackson K, Sheehy KA, Finkel JC, Quezado ZM. The use of dexmedetomidine in pediatric palliative care: a preliminary study. J Palliat Med 2017; 20: 779-783.

10. Katı I, Goktas U, Cagan E, Guzel A, Bartın S. The effect of magnesium sulfate on uncontrollable contractions in a tetanus case. Pediat Emerg Care 2012; 28: 366-367.

11. Attygalle D, Rodrigo N. Magnesium as first line therapy in the management of tetanus: a prospective study of 40 patients. Anaesthesia 2002; 57: 811-817.

12. Hayashida M, Kin N, Tomioka T, et al. Cerebral ischaemia during cardiac surgery in children detected by combined monitoring of BIS and nearinfrared spectroscopy. Br J Anaesth 2004; 92: 662-669.