Background and objectives. The aim of this study was to investigate the factors predicting Pediatric Intensive Care Unit (PICU) mortality and the outcomes in cancer patients admitted to PICU. Methods. We conducted a retrospective study in 48 consecutive cancer patients admitted to the PICU between January 1, 2015 and January 1, 2018. A total of 48 patients (21 males and 27 females) were enrolled in this study. Results. The median age was 77 (33,5-149) months. The median duration of PICU stay was 5 (2-9) days. Patients were classified according to their stage of disease. Ten (20.8%) patients were in the remission group, 9 (18.8%) patients were in the induction period and 29 (60.5%) patients were in the progressive diseasegruops. Thirtynine patients (81.2%) had hematological malignancies, 6 (12.5%) had extracranial solid tumors and 3 (6.3%) had intracranial solid tumors. Thirty-seven patients died and the mortality rate was found to be 77.1%. mortality rates were 11%, 88% and 93% for patients in remission,during induction period and in the progressive disease group, respectively (p
___
1. Heying R, Schneider DT, Korholz D, Stannigel H, Lemburg P, Göbel U. Efficacy and outcome of intensive care in pediatric oncologic patients. Crit Care Med 2001; 29: 2276-2280.
2. Goldstein B, Giroir B. Randolph A; International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6: 2-8.
3. Dursun O, Hazar V, Karasu GT, Uygun V, Tosun O, Yesilipek A. Prognostic factors in pediatric cancer patients admitted to the pediatric intensive care unit. J PediatrHematol Oncol 2009; 31: 481-484.
4. Akhtar N, Fadoo Z, Panju S, Haque A. Outcome and prognostic factors seen in pediatric oncology patients admitted in PICU of a developing country. Indian J Pediatr 2011; 78: 969-972.
5. Ali AM, Sayed HA, Mohammed MM. The outcome of critically Ill pediatric cancer patients admitted to the Pediatric Intensive Care Unit in a Tertiary University Oncology center in a developing country: A 5-year experience. J Pediatr Hematol Oncol 2016; 38: 355-359.
6. Haase R, Lieser U, Kramm C, et al. Management of oncology patients admitted to the paediatricintensive care unit of a general children's hospital - a single center analysis. Klin Padiatr 2011; 223: 142-146.
7. van Gestel JP, Bollen CW, Bierings MB, Boelens JJ, Wulffraat NM, van Vught AJ. Survival in a recent cohort of mechanically ventilated pediatric allogeneic hematopoietic stem cell transplantation recipients. Biol Blood Marrow Transplant 2008; 14: 1385-1393.
8. Pollack MM, Ruttimann UE, Getson PR. Pediatric risk of mortality (PRISM) score. Crit Care Med 1988; 16: 1110-1116.
9. Gonzalez-Vicent M, Marin C, Madero L, Sevilla J, Diaz MA. Risk score for pediatric intensive care unit admission in children undergoing hematopoietic stem cell transplantationand analysis of predictive factors for survival. J Pediatr Hematol Oncol 2005; 27: 526-531.
10. Haase R, Mathony U, Lieser U, Nagel F, Sitka U, Burdach S. Oncology patients in a pediatric intensive care unit–a 7-year experience. Klin Padiatr 2003; 215: 234-240.
11. Hallahan AR, Shaw PJ, Rowell G, O'Connell A, Schell D, Gillis J. Improved outcomes of children with malignancy admitted to a pediatric intensive care unit. Crit Care Med 2000; 28: 3718-3721.