Why is Alzheimer's disease confused with other dementias?

Alzheimer disease (AD) is the most common cause of dementia. The cardinal manifestation of AD is progressive loss of memory. However, there are some nonamnestic presentations of AD, also called atypical AD. Symptoms of AD can sometimes start suddenly. In the presence of atypical symptoms or sudden onset, it may be difficult to distinguish AD from other dementias. We would like to discuss the confusing features of atypical AD that mimic other dementias. In this review, the literature associated with confusing features of AD, suggesting other dementia syndromes, is reviewed. In addition, a case of semantic dementia (SD) with the complaint of forgetfulness previously diagnosed as AD is presented together with clinical and radiological clues of the differential diagnosis of dementia syndromes. As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.

Why is Alzheimer's disease confused with other dementias?

Alzheimer disease (AD) is the most common cause of dementia. The cardinal manifestation of AD is progressive loss of memory. However, there are some nonamnestic presentations of AD, also called atypical AD. Symptoms of AD can sometimes start suddenly. In the presence of atypical symptoms or sudden onset, it may be difficult to distinguish AD from other dementias. We would like to discuss the confusing features of atypical AD that mimic other dementias. In this review, the literature associated with confusing features of AD, suggesting other dementia syndromes, is reviewed. In addition, a case of semantic dementia (SD) with the complaint of forgetfulness previously diagnosed as AD is presented together with clinical and radiological clues of the differential diagnosis of dementia syndromes. As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

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Plasma 8-isoPGF2? and serum melatonin levels in patients with minimal cognitive impairment and Alzheimer disease

Fevziye Burcu ŞİRİN, Duygu Kumbul DOĞUÇ, Hüseyin VURAL, İbrahim EREN, İkbal İNANLI, Recep SÜTCÜ, Namik DELİBAŞ

Molecular docking and ex vivo and in vitro anticholinesterase activity studies ofSalvia sp. and highlighted rosmarinic acid

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Nutritional issues in dementia patients

MUSTAFA KEMAL KILIÇ, FATİH SÜMER, ZEKERİYA ÜLGER

Why is Alzheimer disease confused with other dementias?

İbrahim Levent GÜNGÖR, Dursun AYGÜN

A Turkish 3-center study evaluation of serum folic acid and vitamin B12 levels in Alzheimer disease

Nuriye Nuray ULUSU, Gökhan YILMAZ, Zübeyde ERBAYRAKTAR, Ahmet Turan EVLİCE, Sevgi ARAS, Görsev YENER, Aslihan AVCI

Potential genetic biomarkers in the early diagnosisof Alzheimer disease: APOE and BIN1

GÜLHAN KAYA, ESRA GÜNDÜZ, MURADİYE ACAR, Ömer Faruk HATİPOĞLU, BURCU ACAR, ATİLLA İLHAN, MEHMET GÜNDÜZ

Prevalence of cognitive impairment and related risk factors incommunity-dwelling elderly in Kayseri, Turkey

Sibel ARGUVANLI, Sibel AKIN, Elif Deniz ŞAFAK, Salime MUCUK, Ahmet ÖZTÜRK, Mustafa Mümtaz MAZICIOĞLU, Hatice Duygu KIZILÇAY, Şemsinnur GÖÇER

COGNITIVE PROBLEMS RELATED TO VERTEBRO-BASILAR CIRCULATION

ABDULKADİR KOÇER

The reliability and validity of the Turkish version of theNeuropsychiatric Inventory-Clinician

Eylem Şahin CANKURTARAN, Mustafa DANIŞMAN, Hasan TUTAR, Semra Ulusoy KAYMAK