Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis

Öz Background/aim: The aim of this study was to investigate the prevalence of virulence genes as well as patterns of antibiotic resistance in cystitis and pyelonephritis uropathogenic Escherichia coli (UPEC) isolates. Materials and methods: Two hundred UPEC isolates were collected from hospitalized patients with pyelonephritis (n = 50) and cystitis (n = 150) in Shafa Hospital in Iran. Antimicrobial susceptibility and ESBL production were determined with confirmatory tests. Polymerase chain reaction assay was performed to determine the prevalence of virulence genes in UPEC strains. Results: Of a total 200 UPEC isolates, the highest and lowest resistance rates to antibiotics were for cephalexin (74%) and nitrofurantoin (9%), respectively. Of these isolates, 72 (36%) and 128 (64%) strains were ESBL-positive and ESBL-negative, respectively. The frequency of fimH, papC, and hly was 64%, 38%, and 12%, respectively. The most commonly identified virulence gene in ESBL-positive and ESBL-negative strains was fimH 46 (23%) and 86 (43%), respectively. The hlyA gene was more prevalent among patients with pyelonephritis than cystitis. Conclusion: The frequency of virulence genes was not significantly different between pyelonephritis and cystitis UPEC strains in the studied patients, but the prevalence rates of hlyA and papC genes were higher among UPEC strains isolated from inpatients compared to outpatients; hence, they could be considered as useful targets for prophylactic interventions.

Kaynak Göster

Bibtex @ { tbtkmedical577827, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2019}, volume = {49}, pages = {361 - 367}, doi = {}, title = {Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis}, key = {cite}, author = {Ghazvini, Hosseinali and Taheri, Keyvan and Edalati, Elahe and Miri, Ali and Sedighi, Mansour and Mırkalantarı, Shiva} }
APA Ghazvini, H , Taheri, K , Edalati, E , Miri, A , Sedighi, M , Mırkalantarı, S . (2019). Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis . Turkish Journal of Medical Sciences , 49 (1) , 361-367 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577827
MLA Ghazvini, H , Taheri, K , Edalati, E , Miri, A , Sedighi, M , Mırkalantarı, S . "Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis" . Turkish Journal of Medical Sciences 49 (2019 ): 361-367 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577827>
Chicago Ghazvini, H , Taheri, K , Edalati, E , Miri, A , Sedighi, M , Mırkalantarı, S . "Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis". Turkish Journal of Medical Sciences 49 (2019 ): 361-367
RIS TY - JOUR T1 - Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis AU - Hosseinali Ghazvini , Keyvan Taheri , Elahe Edalati , Ali Miri , Mansour Sedighi , Shiva Mırkalantarı Y1 - 2019 PY - 2019 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 361 EP - 367 VL - 49 IS - 1 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis %A Hosseinali Ghazvini , Keyvan Taheri , Elahe Edalati , Ali Miri , Mansour Sedighi , Shiva Mırkalantarı %T Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis %D 2019 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 49 %N 1 %R %U
ISNAD Ghazvini, Hosseinali , Taheri, Keyvan , Edalati, Elahe , Miri, Ali , Sedighi, Mansour , Mırkalantarı, Shiva . "Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis". Turkish Journal of Medical Sciences 49 / 1 (Şubat 2019): 361-367 .
AMA Ghazvini H , Taheri K , Edalati E , Miri A , Sedighi M , Mırkalantarı S . Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis. Turkish Journal of Medical Sciences. 2019; 49(1): 361-367.
Vancouver Ghazvini H , Taheri K , Edalati E , Miri A , Sedighi M , Mırkalantarı S . Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis. Turkish Journal of Medical Sciences. 2019; 49(1): 361-367.
IEEE H. Ghazvini , K. Taheri , E. Edalati , A. Miri , M. Sedighi ve S. Mırkalantarı , "Virulence factors and antimicrobial resistance in uropathogenic Escherichiacoli strains isolated from cystitis and pyelonephritis", Turkish Journal of Medical Sciences, c. 49, sayı. 1, ss. 361-367, Şub. 2019

9872 8159

Arşiv
Sayıdaki Diğer Makaleler

Prevalence of multiple sclerosis in an urban population of Sivas province in Turkey

Şeyda Figül GÖKÇE, Burhanettin ÇİĞDEM, Sanem Nemmezi KARACA, Asli BOLAYIR, Özlem Kayim YILDIZ, Ahmet Suat TOPAKTAŞ, Hatice BALABAN

Do PD-1 and PD-L2 expressions have prognostic impact in hematologic malignancies?

Serdal KORKMAZ, Selahattin ERDEM, Ebru AKAY, Erdem Arzu TAŞDEMİR, Hatice KARAMAN, Muzaffer KEKLİK

The role of IFIH1 gene rs1990760 and rs2111485 single-nucleotide polymorphisms in generalized vitiligo predisposition

Duru ONAN, Ahu YORULMAZ, Fatih Süheyl EZGÜ, Kadir Mutlu HAYRAN, Seray Külcü ÇAKMAK, Refika Ferda ARTÜZ, Başak YALÇIN

Evaluation of the efficacy of epiduroscopic adhesiolysis in failed back surgery syndrome

Ayşegül CEYLAN, İbrahim AŞIK, Güngör Enver ÖZGENCİL, Burak ERKEN

A comparative biomechanical analysis of suprapectineal and infrapectineal fixation on acetabular anterior column fracture by finite element modeling

Mehmet YÜCENS, Kadir Bahadir ALEMDAROĞLU, Ahmet ÖZMERİÇ, Serkan İLTAR, Ahmet Özgür YILDIRIM, Nevres Hürriyet AYDOĞAN

External validation of anastomotic leakage risk analysis system in patients who underwent colorectal resection

Sadettin ER, Sabri ÖZDEN, Faruk KOCA, Bariş Doğu YILDIZ, Bülent Cavit YÜKSEL, Mesut TEZ

Determination of medication adherence and related factors among people living with HIV/AIDS in a Turkish university hospital

Erdal CEYLAN, Ayşegül KOÇ, Ahmet Çağkan İNKAYA, Serhat ÜNAL

Effects of Ankaferd Hemostat on red blood cell aggregation: a hemorheological study

Rafiye ÇİFTÇİLER, Salih AKSU, Neslihan Hacer Dikmenoğlu FALKMARKEN, İbrahim Celalettin HAZNEDAROĞLU

Serum adropin levels in psoriasis vulgaris and its relation with metabolic parameters

Selma KORKMAZ, Gülben Sayilan ÖZGÜN

S1PR2 deficiency enhances neuropathic pain induced by partial sciatic nerve ligation

Qiang GU, Jin Chao HOU, Xiang Ming FANG