Thyroid malignancy risk in different clinical thyroid diseases

Öz Background/aim: To evaluate the malignancy risk of thyroid nodules in different clinical thyroid diseases. Materials and methods: Patients who underwent thyroidectomy between 2007 and 2014 were grouped as euthyroid, hypothyroid, and hyperthyroid. Further classification was made depending on the presence of solitary/multiple thyroid nodules. Results: Among 2870 patients, 1719 (59.9%) were euthyroid, 962 (33.5%) were hyperthyroid, and 189 (6.6%) were hypothyroid. Overall malignancy was detected in 980 (34.1%) patients. Malignancy rates were 42.1%, 42.9%, and 18.3% in the euthyroid, hypothyroid, and hyperthyroid groups, respectively (P < 0.001). A total 41.4% of patients with euthyroid nodular goiter (ENG) and 46.3% of patients with euthyroid multinodular goiter (EMNG) had thyroid malignancy (P = 0.169). Mean tumor size and capsular and vascular invasion were significantly lower in EMNG than in ENG. Among hypothyroid patients, 45.7% with solitary and 42.2% with multiple nodules were malignant (P = 0.705). When toxic nodular goiter and toxic multinodular goiter were analyzed together, malignancy rate was 24.7% (104/421), and when Graves with nodule/nodules was considered, it was 19.7% (59/299). Conclusion: In hypothyroid or euthyroid patients who underwent thyroidectomy, malignancy rate was higher than 40%, and was lower in hyperthyroid patients. Patients with multiple nodules carry a similar risk of malignancy as patients with solitary nodules, independent of the functional status.

Kaynak Göster

Bibtex @ { tbtkmedical576382, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1509 - 1519}, doi = {}, title = {Thyroid malignancy risk in different clinical thyroid diseases}, key = {cite}, author = {Dirikoç, Ahmet and Fakı, Sevgül and Başer, Hüsniye and Özdemir, Didem and Aydın, Cevdet and Ersoy, Reyhan and Kılıç, Mehmet and Kılıçarslan, Aydan and Çakır, Bekir} }
APA Dirikoç, A , Fakı, S , Başer, H , Özdemir, D , Aydın, C , Ersoy, R , Kılıç, M , Kılıçarslan, A , Çakır, B . (2017). Thyroid malignancy risk in different clinical thyroid diseases . Turkish Journal of Medical Sciences , 47 (5) , 1509-1519 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576382
MLA Dirikoç, A , Fakı, S , Başer, H , Özdemir, D , Aydın, C , Ersoy, R , Kılıç, M , Kılıçarslan, A , Çakır, B . "Thyroid malignancy risk in different clinical thyroid diseases" . Turkish Journal of Medical Sciences 47 (2017 ): 1509-1519 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576382>
Chicago Dirikoç, A , Fakı, S , Başer, H , Özdemir, D , Aydın, C , Ersoy, R , Kılıç, M , Kılıçarslan, A , Çakır, B . "Thyroid malignancy risk in different clinical thyroid diseases". Turkish Journal of Medical Sciences 47 (2017 ): 1509-1519
RIS TY - JOUR T1 - Thyroid malignancy risk in different clinical thyroid diseases AU - Ahmet Dirikoç , Sevgül Fakı , Hüsniye Başer , Didem Özdemir , Cevdet Aydın , Reyhan Ersoy , Mehmet Kılıç , Aydan Kılıçarslan , Bekir Çakır Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1509 EP - 1519 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Thyroid malignancy risk in different clinical thyroid diseases %A Ahmet Dirikoç , Sevgül Fakı , Hüsniye Başer , Didem Özdemir , Cevdet Aydın , Reyhan Ersoy , Mehmet Kılıç , Aydan Kılıçarslan , Bekir Çakır %T Thyroid malignancy risk in different clinical thyroid diseases %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD Dirikoç, Ahmet , Fakı, Sevgül , Başer, Hüsniye , Özdemir, Didem , Aydın, Cevdet , Ersoy, Reyhan , Kılıç, Mehmet , Kılıçarslan, Aydan , Çakır, Bekir . "Thyroid malignancy risk in different clinical thyroid diseases". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1509-1519 .
AMA Dirikoç A , Fakı S , Başer H , Özdemir D , Aydın C , Ersoy R , Kılıç M , Kılıçarslan A , Çakır B . Thyroid malignancy risk in different clinical thyroid diseases. Turkish Journal of Medical Sciences. 2017; 47(5): 1509-1519.
Vancouver Dirikoç A , Fakı S , Başer H , Özdemir D , Aydın C , Ersoy R , Kılıç M , Kılıçarslan A , Çakır B . Thyroid malignancy risk in different clinical thyroid diseases. Turkish Journal of Medical Sciences. 2017; 47(5): 1509-1519.
IEEE A. Dirikoç , S. Fakı , H. Başer , D. Özdemir , C. Aydın , R. Ersoy , M. Kılıç , A. Kılıçarslan ve B. Çakır , "Thyroid malignancy risk in different clinical thyroid diseases", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1509-1519, Eki. 2017

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