The assessment of skin sebum and moisture content of infants with atopic dermatitis

Background/aim: Atopic dermatitis AD is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematous lesions. The aim of this study is to evaluate the skin moisture and sebum content of the infants with AD and its relationship between the disease severity. Materials and methods: For this cross-sectional and case-control study we included 49 infants with AD aged between 2 and 24 months and 34 healthy infants with the same age and sex as a control group. Skin moisture and sebum content were measured by the bio- impedance method and recorded. Skin prick tests, total IgE levels and food-specific milk, egg IgE levels were performed. Results: There was a significant difference between the groups in terms of mean skin moisture and sebum content percentage P

___

  • 1. Gupta J, Grube E, Ericksen MB, Stevenson MD, Lucky AW et al. Intrinsically defective skin barrier function in Children with atopic dermatitis correlates with disease severity. The Journal Allergy and Clinical Immunology 2008; 121 (3): 725-730.e2. doi:10.1016/j.jaci.2007.12.1161. Epub 2008 Feb 4.
  • 2. Martinsen ØG, Grimnes S, Kirkhus T, Mørkrid L, Aas K. Increased moisture content in children’s atopic skin. European Journal of Pediatric Dermatolology 2007; 17: 17-20.
  • 3. Lodén M, Olsson H, Axéll T, Linde YW. Friction, capacitance and transepidermal water loss (TEWL) in dry atopic and normal skin. The British Journal of Dermatology 1992; 126 (2): 137-141. doi: 10.1111/j.1365-2133.1992.tb07810.x
  • 4. Sator PG, Schmidt JB, Hönigsmann H. Comparison of epidermal hydration and skin surface lipids in healthy individuals and in patients with atopic dermatitis. Journal of American Academy of Dermatology 2003; 48 (3):352-358. doi: 10.1067/mjd.2003.105
  • 5. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermato-venereologica Suppl 1980; 92: 44-47.
  • 6. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186: 23-31. doi: 10.1159/000247298
  • 7. Tupker RA, Pinnagoda J, Coenraads PJ, Nater JP. Susceptibility to irritants: role of barrier function, skin dryness and history of atopic dermatitis. The British Journal of Dermatology 1990; 123: 199-205. doi: 10.1111/j.1365-2133.1990.tb01847.x
  • 8. Werner Y. The water content of the stratum corneum in patients with atopic dermatitis. Measurement with the Corneometer CM 420. Acta Dermato-venereologica 1986; 66: 281-284.
  • 9. Gloor M, Heymann B, Stuhlert T. Infrared-spectroscopic determination of the water content of the horny layer in healthy subjects and in patients suffering from atopic dermatitis. Archives of Dermatological Research 1981; 271: 429-436. doi: 10.1007/bf00406688
  • 10. Finlay AY, Nicholls S, King CS, Marks R. The “dry’ noneczematous skin associated with atopic eczema.The British Journal of Dermatology 1980; 102: 249-256. doi: 10.1111/ j.1365-2133.1980.tb07241.x
  • 11. GürÇetinkaya P, Şahiner ÜM. Childhood atopic dermatitis: current developments, treatment approaches, and future expectations. Turkish Journal of Medical Sciences 2019; 49 (4): 963-984. doi: 10.3906/sag-1810-105
  • 12. Jiang Y, Ma W. Assessment of neutrophil-to-lymphocyte ratio and platelet-tolymphocyte ratio in atopic dermatitis patients. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2017; 17 (23): 1340-1346. doi: 10.12659/ msm.900212
  • 13. Tang TS, Bieber T, Williams HC. Are the concepts of induction of remission and treatment of subclinical inflammation in atopic dermatitis clinically useful? The Journal of Allergy and Clinical Immunology 2014; 133: 1615-1625.e1. doi: 10.1016/j. jaci.2013.12.1079
  • 14. Mu Z, Zhao Y, Liu X, Chang C, Zhang J. Molecular biology of atopic dermatitis. Clinical Reviews in Allergy & Immunology 2014; 47: 193-218. doi: 10.1007/s12016-014-8415-1
  • 15. Vekaria AS, Brunner PM, Aleisa AI, Bonomo L, Lebwohl MG et al. Moderate-to-severe atopic dermatitis patients show increases in serum C-reactive protein levels, correlating with skin disease activity. Version 2. F1000Res. 2017; 6: 1712. doi: 10.12688/f1000research.12422.2
  • 16. Akdis CA, Akdis M, Bieber T, Bindslev-Jensen C, Boguniewicz M et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. Allergy 2006; 61 (8): 969-87.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Hande YEĞENOĞLU AKÇINAR, Belma ASLIM, Hilal TORUL, Burcu GÜVEN, Adem ZENGİN, Zekiye SULUDERE, İsmail Hakkı BOYACI, Uğur TAMER

Ocular toxicity of intravitreal golimumab in a rabbit model

Alper BAĞRIYANIK, Bekir Uğur ERGÜR, Ceren DURMAZ ENGİN, Serap CİLAKER MIÇILI, Osman YILMAZ, Fatoş ÖNEN, Ali Osman SAATCİ

Comparison of mesenchymal stem cell sheets and chondrocyte sheets in a rabbit growth plate injury model

Erdal KARAÖZ, Alper GÜLTEKİN, Yücel AĞIRDİL, Büşra Öncel DUMAN, Cansu Subaşı DEMİR

Comparison the accuracy and trending ability of cardiac index measured by the fourthgeneration of FloTrac with the PiCCO device in septic shock patients

Bodin KHWANNIMIT, Rattina JOMSURIYA

Does capsaicin have therapeutic benefits in human colon adenocarcinoma? Selection of the most reliable dose via AgNOR

Mustafa NİSARİ, Recep ERÖZ

Lılııa NAZAROVA, Ksenıa DANILKO, Vıktor MALIEVSKY, Denıs KARIMOV, Akhat BAKIROV, Tatıana VIKTOROVA

Surgical considerations and audiological results of cochlear implantation in patients with otosclerosis

Tolgahan ÇATLI, Ergül Başaran BOZKURT, Uğurtan ERGÜN, Enver ALTAŞ, Taşkın TOKAT, Zehra Hilal ADIBELLİ, Levent OLGUN

Ertuğrul Emre GÜNTÜRK, Oğuzhan BARAN, Hasan AKKAYA, Özcan ÖRSÇELİK

Çağrı DAMAR, Betül Emine DERİNKUYU, Muazzez Asburçe Bike Olgaç KILIÇKAYA, Mehmet ÖZTÜRK, Çiğdem ÖZTUNALI, Ayşe Gül ALIMLI, Öznur Leman BOYUNAGA, Murat UÇAR, Fatih Süheyl EZGÜ, Leyla TÜMER, Alp Özgün BÖRCEK, Ahmet SIĞIRCI

Evaluation of the effect of percutaneous mitral balloon valvuloplasty on left ventricular systolic functions using strain and strain rate echocardiography

Hasan AKKAYA, Ertuğrul Emre GÜNTÜRK, Oğuzhan BARAN, Özcan ÖRSÇELİK