OYA YALÇIN ÇOK, Hatice Evren EKER, Aniş ARIBOĞAN

Ketamine dosing for sedation during repeated radiotherapy sessions in children

Öz Background/aim: We report the analysis of ketamine doses needed and the recovery times in pediatric oncology patients undergoing repeated radiotherapy sessions. Materials and methods: In a single-blind prospective study design, thirty-three pediatric patients undergoing radiotherapy due to oncologic disorders received 2 mg/kg ketamine and 10 μg/kg atropine intravenously and the rescue drug to be administered was ketamine at 0.5 mg/kg when the sedation level was inadequate. Total ketamine consumption, additional doses, and recovery time were recorded. Results: Data of 635 consecutive radiotherapy sessions were evaluated. There was no significant alteration in total ketamine consumption required to complete the radiotherapy periods during consecutive procedures (P > 0.05). However, the recovery times started to decrease by the fourth session (P = 0.02) and continued to decrease onwards during the whole study period (P = 0.001). The mean of the first recovery time was 13.68 ± 3.99 min, whereas the mean of the last recovery time was 7.66 ± 6.35 min. Conclusion: A requirement for an incremental increase in ketamine dose after subsequent administrations was not detected, despite a significant decrease in recovery times being anticipated when ketamine is used repeatedly for sedative purposes in consecutive radiotherapy sessions.

Anahtar Kelimeler:

Ketamine, sedation, radiotherapy, pediatrics, tolerance

Tam Metin

Kaynak Göster

Bibtex	`@ { tbtkmedical576736, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2018}, volume = {48}, pages = {851 - 855}, doi = {}, title = {Ketamine dosing for sedation during repeated radiotherapy sessions in children}, key = {cite}, author = {Çok, OYA YALÇIN and Eker, Hatice Evren and Arıboğan, Aniş} }`
APA	Çok, O , Eker, H , Arıboğan, A . (2018). Ketamine dosing for sedation during repeated radiotherapy sessions in children . Turkish Journal of Medical Sciences , 48 (4) , 851-855 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45702/576736
MLA	Çok, O , Eker, H , Arıboğan, A . "Ketamine dosing for sedation during repeated radiotherapy sessions in children" . Turkish Journal of Medical Sciences 48 (2018 ): 851-855 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45702/576736>
Chicago	Çok, O , Eker, H , Arıboğan, A . "Ketamine dosing for sedation during repeated radiotherapy sessions in children". Turkish Journal of Medical Sciences 48 (2018 ): 851-855
RIS	TY - JOUR T1 - Ketamine dosing for sedation during repeated radiotherapy sessions in children AU - OYA YALÇIN Çok , Hatice Evren Eker , Aniş Arıboğan Y1 - 2018 PY - 2018 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 851 EP - 855 VL - 48 IS - 4 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote	%0 Turkish Journal of Medical Sciences Ketamine dosing for sedation during repeated radiotherapy sessions in children %A OYA YALÇIN Çok , Hatice Evren Eker , Aniş Arıboğan %T Ketamine dosing for sedation during repeated radiotherapy sessions in children %D 2018 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 48 %N 4 %R %U
ISNAD	Çok, OYA YALÇIN , Eker, Hatice Evren , Arıboğan, Aniş . "Ketamine dosing for sedation during repeated radiotherapy sessions in children". Turkish Journal of Medical Sciences 48 / 4 (Ağustos 2018): 851-855 .
AMA	Çok O , Eker H , Arıboğan A . Ketamine dosing for sedation during repeated radiotherapy sessions in children. Turkish Journal of Medical Sciences. 2018; 48(4): 851-855.
Vancouver	Çok O , Eker H , Arıboğan A . Ketamine dosing for sedation during repeated radiotherapy sessions in children. Turkish Journal of Medical Sciences. 2018; 48(4): 851-855.
IEEE	O. Çok , H. Eker ve A. Arıboğan , "Ketamine dosing for sedation during repeated radiotherapy sessions in children", Turkish Journal of Medical Sciences, c. 48, sayı. 4, ss. 851-855, Ağu. 2018