Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease

Öz Background/aim: The aim of the study was to investigate the effects of whole blood viscosity and plasma nitric oxide on cerebral and cardiovascular risks associated with chronic kidney disease. Materials and methods: The study group consisted of 40 pediatric patients and 21 healthy control subjects. Hematologic and biochemical variables, viscosity and plasma nitric oxide levels, echocardiographic findings, and middle cerebral artery blood flow velocity were examined. Results: Viscosity values of patients were significantly lower than those of the control group. Lower values of hematocrit, total protein, and albumin and higher values of ferritin in all patient groups resulted in significantly low viscosity levels. Plasma nitric oxide levels were higher in all patient groups than those in the controls. No statistically significant difference was present in middle cerebral artery blood flow velocity between the patient and control groups. Even when systolic functions were normal, the patient group had significant deterioration in diastolic functions, suggesting morbidity and mortality risks. Conclusions: Cerebral blood flow velocities were not affected by viscosity and nitric oxide levels, suggesting that cerebral circulation has the ability to make adaptive modulation. The metabolism of nitric oxide levels needs further investigation and studies in patients with chronic renal disease.

Kaynak Göster

Bibtex @ { tbtkmedical576377, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1482 - 1491}, doi = {}, title = {Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease}, key = {cite}, author = {Buyan, Necla and Akçaboy, Meltem and Göktaş, Tayfun and Kula, Serdar and Nazlıel, Bijen and Çakar, Nilgün and Uncu, Nermin and Çelik, Bülent and Erbaş, Deniz} }
APA Buyan, N , Akçaboy, M , Göktaş, T , Kula, S , Nazlıel, B , Çakar, N , Uncu, N , Çelik, B , Erbaş, D . (2017). Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease . Turkish Journal of Medical Sciences , 47 (5) , 1482-1491 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576377
MLA Buyan, N , Akçaboy, M , Göktaş, T , Kula, S , Nazlıel, B , Çakar, N , Uncu, N , Çelik, B , Erbaş, D . "Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease" . Turkish Journal of Medical Sciences 47 (2017 ): 1482-1491 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576377>
Chicago Buyan, N , Akçaboy, M , Göktaş, T , Kula, S , Nazlıel, B , Çakar, N , Uncu, N , Çelik, B , Erbaş, D . "Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease". Turkish Journal of Medical Sciences 47 (2017 ): 1482-1491
RIS TY - JOUR T1 - Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease AU - Necla Buyan , Meltem Akçaboy , Tayfun Göktaş , Serdar Kula , Bijen Nazlıel , Nilgün Çakar , Nermin Uncu , Bülent Çelik , Deniz Erbaş Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1482 EP - 1491 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease %A Necla Buyan , Meltem Akçaboy , Tayfun Göktaş , Serdar Kula , Bijen Nazlıel , Nilgün Çakar , Nermin Uncu , Bülent Çelik , Deniz Erbaş %T Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD Buyan, Necla , Akçaboy, Meltem , Göktaş, Tayfun , Kula, Serdar , Nazlıel, Bijen , Çakar, Nilgün , Uncu, Nermin , Çelik, Bülent , Erbaş, Deniz . "Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1482-1491 .
AMA Buyan N , Akçaboy M , Göktaş T , Kula S , Nazlıel B , Çakar N , Uncu N , Çelik B , Erbaş D . Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease. Turkish Journal of Medical Sciences. 2017; 47(5): 1482-1491.
Vancouver Buyan N , Akçaboy M , Göktaş T , Kula S , Nazlıel B , Çakar N , Uncu N , Çelik B , Erbaş D . Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease. Turkish Journal of Medical Sciences. 2017; 47(5): 1482-1491.
IEEE N. Buyan , M. Akçaboy , T. Göktaş , S. Kula , B. Nazlıel , N. Çakar , N. Uncu , B. Çelik ve D. Erbaş , "Effects of whole blood viscosity and plasma NOx on cardiac function and cerebral blood flow in children with chronic kidney disease", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1482-1491, Eki. 2017

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