Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids

Öz Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Materials and methods: In our series, ten patients had EN bilaterally, whereas one patient had a lesion of the right pretibial area. The mean age of the patients was 35.5 years (range: 29-45 years). IGM and EN were diagnosed by the necessary serological, microbiological, radiological, and histopathological examination. After diagnosis, methylprednisolone was started in the first week at 0.8 mg/kg daily for treatment. The weekly dose was tapered to 0.1 mg/kg daily over 8 weeks.Results: We started with the treatment of methylprednisolone, and in all our cases the initial response was excellent. In 2 weeks the IGM symptoms had markedly declined, while signs of EN disappeared completely. Patients were followed for an average of 60 months after treatment. None of the 11 patients had recurrence.Conclusion: We herein report a rare series considering IGM cases complicated by EN. Few such cases have been reported in the literature. We advocate for an initial trial of methylprednisolone treatment, which proved to be very successful in our patients.

Kaynak Göster

Bibtex @ { tbtkmedical576393, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1590 - 1592}, doi = {}, title = {Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids}, key = {cite}, author = {Akın, Murat and Karabacak, Harun and Esendağlı, Güldal and Yavuz, Aydin and Gültekin, Serap and Dikmen, Kürşat and Bostancı, Hasan} }
APA Akın, M , Karabacak, H , Esendağlı, G , Yavuz, A , Gültekin, S , Dikmen, K , Bostancı, H . (2017). Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids . Turkish Journal of Medical Sciences , 47 (5) , 1590-1592 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576393
MLA Akın, M , Karabacak, H , Esendağlı, G , Yavuz, A , Gültekin, S , Dikmen, K , Bostancı, H . "Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids" . Turkish Journal of Medical Sciences 47 (2017 ): 1590-1592 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576393>
Chicago Akın, M , Karabacak, H , Esendağlı, G , Yavuz, A , Gültekin, S , Dikmen, K , Bostancı, H . "Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids". Turkish Journal of Medical Sciences 47 (2017 ): 1590-1592
RIS TY - JOUR T1 - Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids AU - Murat Akın , Harun Karabacak , Güldal Esendağlı , Aydin Yavuz , Serap Gültekin , Kürşat Dikmen , Hasan Bostancı Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1590 EP - 1592 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids %A Murat Akın , Harun Karabacak , Güldal Esendağlı , Aydin Yavuz , Serap Gültekin , Kürşat Dikmen , Hasan Bostancı %T Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD Akın, Murat , Karabacak, Harun , Esendağlı, Güldal , Yavuz, Aydin , Gültekin, Serap , Dikmen, Kürşat , Bostancı, Hasan . "Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1590-1592 .
AMA Akın M , Karabacak H , Esendağlı G , Yavuz A , Gültekin S , Dikmen K , Bostancı H . Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids. Turkish Journal of Medical Sciences. 2017; 47(5): 1590-1592.
Vancouver Akın M , Karabacak H , Esendağlı G , Yavuz A , Gültekin S , Dikmen K , Bostancı H . Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids. Turkish Journal of Medical Sciences. 2017; 47(5): 1590-1592.
IEEE M. Akın , H. Karabacak , G. Esendağlı , A. Yavuz , S. Gültekin , K. Dikmen ve H. Bostancı , "Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1590-1592, Eki. 2017

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