Sulfonic acid-functionalized silica: a remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 1,4-dihydropyridines

An efficient one-pot method for the synthesis of 1,4-dihydropyridines from b-dicarbonyl compounds, aldehyde, and ammonium acetate is reported using sulfonic acid-functionalized silica at 90 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable (up to 300 °C), reusable, and efficiently used under reaction conditions.

Sulfonic acid-functionalized silica: a remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 1,4-dihydropyridines

An efficient one-pot method for the synthesis of 1,4-dihydropyridines from b-dicarbonyl compounds, aldehyde, and ammonium acetate is reported using sulfonic acid-functionalized silica at 90 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable (up to 300 °C), reusable, and efficiently used under reaction conditions.

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Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
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