New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a $p$-phenylazo bridge and the structural characterizations were achieved by FT IR, $^{1}$H and $^{13}$C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely \textit{Acinetobacter calcoaceticus} (ATCC23055), \textit{Escherichia coli} (ATCC2592), \textit{Pseudomonas aeruginosa} (ATCC27853), and \textit{Staphylococcus aureus} (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.

New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a $p$-phenylazo bridge and the structural characterizations were achieved by FT IR, $^{1}$H and $^{13}$C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely \textit{Acinetobacter calcoaceticus} (ATCC23055), \textit{Escherichia coli} (ATCC2592), \textit{Pseudomonas aeruginosa} (ATCC27853), and \textit{Staphylococcus aureus} (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.
Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Corrosion inhibition by naturally occurring Hibiscus sabdariffa plant extract on a mild steel alloy in HCl solution

MAGDA ABDO MAHMOUD AMEER, AMANY MOHAMED FEKRY

A new series of Cu(II) and Ni(II) complexes of NO bidentate 4-NO2 -benzoylhydrazones: synthesis, characterization, and biological studies

Hatice KÜÇÜK BAŞPINAR, Berna ÇELİK ÖZBEK, Emel KARA MATARACI

A new series of Cu(II) and Ni(II) complexes of NO bidentate 4-NO$_{2}$-benzoylhydrazones: synthesis, characterization, and biological studies

HATİCE BAŞPINAR KÜÇÜK, EMEL MATARACI KARA, BERNA ÖZBEK ÇELİK

Influence of acid and heavy metal cation exchange treatments on methane adsorption properties of mordenite

MERYEM SAKIZCI, LEYLA ÖZGÜL KILINÇ

Thermogravimetric analysis-based screening of metal (II) chlorides as dopants for the destabilization of solid-state hydrazine borane

WEIGUANG CHEN, UMIT BILGE DEMIRCI

Properties and some in vitro studies of 6-phosphogluconate dehydrogenase purified from the liver of Chalcalburnus tarichi, the only fish living in Lake Van's highly alkaline water (pH 9.8)

Mehmet Rıza KIVANÇ, Muhammet GÜLER, Vedat TÜRKOĞLU

Synthesis of novel 1,2,4-triazoles and triazolo-thiadiazines as anticancer agents

THORAYA ABD EL-REHEEM FARGHALY, MAGDA AHMAD ABDALLAH, HUDA KAMEL MMAHMOUD

Spectrophotometric determination of iron species using ionic liquid ultrasound assisted dispersive liquid liquid microextraction

Alireza SHAMILI BAZMANDEGAN, Ali Mohammad SHABANI HAJI, Mahboubeh SAEIDI, Masoud MOGHADAM ROHANI, Shayessteh DADFARNIA

Spectrophotometric determination of iron species using ionic liquid ultrasound assisted dispersive liquid--liquid microextraction

ALIREZA BAZMANDEGAN, ALI MOHAMMAD HAJI SHABANI, SAYESSTEH DADFARNIA, MAHBOUBEH SAEIDI, MASOUD ROHANI MOGHADAM

Preparation and physicochemical characterizations of solid lipid nanoparticles containing DOTAP⃝R for DNA delivery

Gülay BÜYÜKKÖROĞLU, Ayşe Filiz ÖNER, Emine Yasemin YAZAN