Hayriye Eda SATANA KARA, Burak DEMİRHAN, Buket ER DEMİRHAN

Highly luminescent water-dispersed silicon quantum dots for fluorometric determination of oxytetracycline in milk samples

A fluorescent probe based on silicon quantum dots (SiQDs) was developed for the selective and sensitive detection of oxytetracycline (OTC) via the inner filter effect (WE). The water-soluble fluorescent SiQD was synthesized based on the reaction of 3-Aminopropyltriethoxysilane (APTES) and sodium citrate as precursors by the one-pot hydrothermal process. The strong fluorescence emission of quantum dots (QDs) was obtained at 440 nm when excited at 350 nm and OTC had a broad absorption band between 200 and 400 nm. The excitation spectrum of SiQDs was completely overlapped with the absorption spectrum of OTC. The light at an excitation wavelength of QDs absorbed by OTC caused a decrease in fluorescence intensity with an increase in the concentration of OTC. Under optimal conditions, the linear concentration range was 0.92-9.2 mu g mL(-1) with a detection limit (LOD; S/N = 3) of 0.19 mu g mL(-1). The proposed method was applied to the determination of OTC in milk samples and satisfactory recoveries (98.8-100.5%) with low RSD % values (0.93-2.31%) were achieved. This simple, selective, sensitive, rapid, and cheap method can be used as a promising tool for OTC analysis in food safety.

Keywords:

Silicon quantum dots oxytetracycline, fluorescent probe, inner filter effect,

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BATCHELDER AR, 1981, J ENVIRON QUAL, V10, P515, DOI 10.2134/jeq1981.00472425001000040019x
Chafer-Pericas C, 2010, ANAL CHIM ACTA, V662, P177, DOI 10.1016/j.aca.2009.12.044
Chen CH, 2018, ANAL LETT, V51, P2895, DOI 10.1080/00032719.2018.1456547
Chen YN, 2016, FOOD ANAL METHOD, V9, P905, DOI 10.1007/s12161-015-0262-z
Chopra I, 2001, MICROBIOL MOL BIOL R, V65, P232, DOI 10.1128/MMBR.65.2.232-260.2001
Demirhan B, 2019, FRESEN ENVIRON BULL, V28, P2599
Furusawa N, 2003, CHROMATOGRAPHIA, V57, P317, DOI 10.1007/BF02492402
GIL EP, 1989, FRESEN Z ANAL CHEM, V335, P1002, DOI 10.1007/BF00466397
He BS, 2019, FOOD CHEM, V300, DOI 10.1016/j.foodchem.2019.125179
JELIKICSTANKOV M, 1989, J PHARMACEUT BIOMED, V7, P1565, DOI 10.1016/0731-7085(89)80166-9
Kang ZH, 2009, ADV MATER, V21, P661, DOI 10.1002/adma.200801642
KUBISTA M, 1994, ANALYST, V119, P417, DOI 10.1039/an9941900417
Kurjogi M, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0223475
Lakowicz J.R., 1999, PRINCIPLES FLUORESCE
Leon-Aguirre K, 2019, B ENVIRON CONTAM TOX, V103, P610, DOI 10.1007/s00128-019-02701-2
Li J, 2018, J SEP SCI, V41, DOI 10.1002/jssc.201800683
Lin JT, 2015, RSC ADV, V5, P27458, DOI 10.1039/c5ra01769f
Liu YN, 2018, SENSOR ACTUAT B-CHEM, V275, P415, DOI 10.1016/j.snb.2018.08.073
Casarrubias-Torres LM, 2018, ACTA VET BRNO, V87, P181, DOI 10.2754/avb201887020181
Marinou E, 2019, SEPARATIONS, V6, DOI 10.3390/separations6020021
Patyra E, 2015, POL J VET SCI, V18, P283, DOI 10.1515/pjvs-2015-0037
Paul P, 2019, CHROMATOGRAPHIA, V82, P1395, DOI 10.1007/s10337-019-03755-4
Sandhu, 2007, WIDE BANDGAP SEMICON .
Satana Kara HE., 2019, TURK J CHEM, V43, P125, DOI [10.3906/kim-1807-59, DOI 10.3906/KIM-1807-59]
Sun JY, 2015, ANAL LETT, V48, P100, DOI 10.1080/00032719.2014.930874
UENO R, 1992, J CHROMATOGR-BIOMED, V573, P333, DOI 10.1016/0378-4347(92)80139-H
Virolainen NE, 2008, J AGR FOOD CHEM, V56, P11065, DOI 10.1021/jf801797z
Wang JJ, 2016, SENSOR ACTUAT B-CHEM, V237, P740, DOI 10.1016/j.snb.2016.06.157
Wang YL, 2016, SENSOR ACTUAT B-CHEM, V236, P621, DOI 10.1016/j.snb.2016.06.029
Wang Z, 2019, CHEMOSPHERE, V230, P337, DOI 10.1016/j.chemosphere.2019.05.047
Warner JH, 2005, ANGEW CHEM INT EDIT, V44, P4550, DOI 10.1002/anie.200501256
Wu FG, 2015, ADV MATER INTERFACES, V2, DOI 10.1002/admi.201500360
Wu XY, 2016, ELECTROPHORESIS, V37, P2963, DOI 10.1002/elps.201600189
Xu N, 2017, RSC ADV, V7, P48429, DOI 10.1039/c7ra09338a
Xu W, 2019, MICROCHIM ACTA, V186, DOI 10.1007/s00604-019-3751-8
Zeghbroeck BV, 2011, PRINCIPLES SEMICONDU
Zhong YL, 2015, ACS NANO, V9, P5958, DOI 10.1021/acsnano.5b00683
Zhong YL, 2013, J AM CHEM SOC, V135, P8350, DOI 10.1021/ja4026227
Zhong YL, 2012, ANGEW CHEM INT EDIT, V51, P8485, DOI 10.1002/anie.201202085
Zhu CY, 2017, INSTRUM SCI TECHNOL, V45, P219, DOI 10.1080/10739149.2016.1215995