Birgül Özden KASIMOĞULLARI, Zafer CESUR

3412

Fused Heterocycles: Synthesis of Some New Imidazopyridines as Anti-Mycobacterial Agents

The reaction of semicarbazones bearing an imidazo[1,2-a]pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H37Rv, using rifampin as the standard. Only IVe showed activity at 6.25 m g mL-1.

Anahtar Kelimeler:

Imidazo[1, 2-a]pyridine, semicarbazones, 4-thiazolidinone, antituberculous activity

Fused Heterocycles: Synthesis of Some New Imidazopyridines as Anti-Mycobacterial Agents

The reaction of semicarbazones bearing an imidazo[1,2-a]pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H37Rv, using rifampin as the standard. Only IVe showed activity at 6.25 m g mL-1.

Keywords:

Imidazo[1, 2-a]pyridine, semicarbazones, 4-thiazolidinone, antituberculous activity,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: Yılda 6 Sayı
Yayıncı: TÜBİTAK

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