Differential pulse voltammetric determination of dopamine using Pd nanoparticles deposited on (3-aminopropyl)triethoxysilane functionalized CeO 2 nanoparticles

In this study, a novel and effective electrochemical sensor for determination of dopamine (DA) was successfully developed by the modification of a glassy carbon electrode (GCE) using Pd nanoparticles deposited on (3-aminopropyl)triethoxysilane functionalized nanoceria (Pd@CeO22_{2}-APTES) and nafion used as a protective membrane. The synthesized nanocomposites were evaluated using X-ray diffraction, high-resolution transmission electron microscopy, and Fourier transform infrared spectroscopy. Moreover, the electrochemical properties of the modified electrodes were investigated using cyclic voltammetry, electrochemical impedance voltammetry, and differential pulse voltammetry (DPV). The Nf/Pd@CeO22_{2}-APTES/GCE showed a linear range of 2.5--149.5 μμ\mu M for DA by DPV with a notable sensitivity of 3.89 mA mM−1−1^{-1\, }cm−2−2^{-2} and a low limit of detection of 0.46 μμ\mu M based on the signal-to-noise ratio of 3 (S/N = 3). In addition, the sensor exhibited satisfactory selectivity, remarkable sensitivity, repeatability, and reproducibility. The sensor protected 92.07{\%} of its initial electrocatalytic activity toward the oxidation of dopamine after 30 days. The Nf/Pd@CeO22_{2}-APTES/GCE was used for determination of DA in serum samples. The results indicate that the sensor can be a notable device for the detection of DA in biological fluids.

Keywords:

Pd nanoparticles, (3-aminopropyl)triethoxysilane, nanoceria, differential pulse voltammetry dopamine,

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Robinson, D. L.; Venton, B. J.; Heien, M. L. A. V.; Wightman, R. M. Clin. Chem. 2003 , 49 , 1763-1773.
Hefco, V.; Yamada, K.; Hefco, A.; Hritcu, L.; Tiron, A.; Nabeshima, T.; Eur. J. Pharmacol. 2003 , 475 , 55-60.
Hyman, S. E.; Malenka, R. C. Nat. Rev. Neurosci. 2001 , 2 , 695-703.
De Benedetto, G. E.; Fico, D.; Pennetta, A.; Malitesta, C.; Nicolardi, G.; Lofrumento, D. D.; De Nuccio, F.; La Pesa, V. J. Pharm. Biomed. Anal. 2014 , 98 , 266-270.
Li, X.; Lu, X.; Kan, X. J. Electroanal. Chem. 2017 , 799 , 451-458.
Rithesh Raj, D.; Prasanth, S.; Vineeshkumar, T. V.; Sudarsanakumar, C. Sens. Act. B Chem. 2016 , 224 , 600-606.
Üğe, A.; Koyuncu Zeybek, D.; Zeybek, B. J. Electroanal. Chem. 2018 , 813 , 134-142.
Suzuki, Y. Sens. Act. B Chem. 2017 , 239 , 383-389.
Wen, D.; Liu, W.; Herrmann, A. K.; Haubold, D.; Holzschuh, M.; Simon, F.; Eychmüller, A. Small 2016 , 12 , 2439-2442.
Li, L. L.; Liu, H. Y.; Shen, Y. Y.; Zhang, J. R.; Zhu, J. J. Anal. Chem. 2011 , 83 , 661-665.
van Staden, J. F.; van Staden, R. I. S. Talanta 2012 , 102 , 34-43.
Anithaa, A. C.; Lavanya, N.; Asokan, K.; Sekar, C. Electrochim. Acta 2015 , 167 , 294-302.
Zhao, C.; Jiang, Z.; Cai, X.; Lin, L.; Lin, X.; Weng, S. J. Electroanal. Chem. 2015 , 748 , 16-22.
Alexander, C.; Bandyopadhyay, K. Inorg. Chim. Acta 2017 , 468 , 171-176.
Wang, J.; Yang, B.; Zhong, J.; Yan, B.; Zhang, K.; Zhai, C.; Shiraishi, Y.; Du, Y.; Yang, P. J. Coll. Interface Sci. 2017 , 497 , 172-180.
Guler, M.; Turkoglu, V.; Kivanc, M. R. Electroanal. 2017 , 29 , 2507-2515.
Guler, M.; Turkoglu, V.; Bulut, A.; Zahmakiran, M. Electrochem. Acta 2018 , 263 , 118-126.
Bisht, A.; Gangwar, B. P.; Anupriya, T.; Sharma, S. J. Solid State Electrochem. 2014 , 18 , 197-206.
Sun, C.; Li, H.; Chen, L. Energy Environ. Sci. 2012 , 5 , 8475-8505.
Liu, H. J.; Feng, Z. Y.; Huang, X. W.; Long, Z. Q.; Wang, M.; Xiao, Y. F.; Hou, Y. K. J. Rare Earths 2013 , 31 , 174-179.
Chen, L.; Si, Z. C.; Wu, X. D.; Weng, D.; Ran, R.; Yu, J. J. Rare Earths 2014 , 32 , 907-917.
Guler, M.; Turkoglu, V.; Basi, Z. Electrochim. Acta 2017 , 240 , 129-135.
Tan, L.; Zhou, K. G.; Zhang, Y. H.; Wang, H. X.; Wang, X. D.; Guo, Y. F.; Zhang, H.L. Electrochem. Commun. 2010 , 12 , 557-560.
Gan, T.; Sun, J.; Cao, S.; Gao, F.; Zhang, Y.; Yang, Y. Electrochem. Acta 2012, 74, 151-157.
Bard, A. J.; Faulkner, L. R. Electrochemical Methods: Fundamentals and Applications ; John Wiley and Sons: Hoboken, NJ, USA, 2000.
Konopka, S. J.; McDuffie, B. Anal. Chem. 1970 , 42 , 1741-1746.
Laviron, E. J: Electroanal. Chem. Interfacial Electrochem . 1970 , 101 , 19-28.
Huang, J.; Liu, Y.; Hou, H.; You, T. Biosens. Bioelectron. 2008 , 24 , 632-637.
Aparna, T. K.; Sivasubramanian, R.; Dar, M. A. J. Alloy Compd. 2018 , 741 , 1130-1141.
Devnani, H.; Ansari, S.; Satsangee, S. P.; Jain R. Mater. Today Chem. 2017 , 4 , 17-25.
Zhu, Q.; Bao, J.; Huo, D.; Yang, M.; Wu, H.; Hou, C.; Zhao, Y.; Luo, X.; Fa, H. J. Electroanal. Chem. 2017 , 799 , 459-467.
Fazioa, E.; Spadaro, S.; Bonsignore, M.; Lavanya, N.; Sekar, C.; Leonardi, S. G.; Neri, G.; Neri, F. J. Electroanal. Chem. 2018 , 814 , 91-96.
Chu, K.; Wang, F.; Zhao, X. L.; Wang, X. W.; Tian, Y. Mater. Sci. Eng. C 2017 , 81 , 452-458.
Zhao, L.; Cai, Z.; Yao, Q.; Zhao, T.; Lin, H.; Xiao, Y.; Chen, X. Sens. Act. B Chem. 2017 , 252 , 1113-1119.
Cheng, M.; Zhang, X.; Wang, M.; Huang, H.; Ma, J. J. Electroanal. Chem. 2017 , 786 , 1-7.
Atta, N. F.; El-Kady, M. F.; Galal, A. Anal. Biochem. 2010 , 400 , 78-88.
Thiagarajan, S.; Yang, R. F.; Chen, S. -M. Bioelectrochem. 2009 , 75 , 163-169.
Yadav, S. K.; Rosy, Oyama, M.; Goyal, R. N. J. Electrochem. Soc. 2014 , 161 , H41-H46.
Wang, X.; Wu, M.; Tang, W.; Zhu, Y.; Wang, L.; Wang, Q.; He, P.; Fang, Y. J. Electroanal. Chem. 2013, 695 , 10-16.
Palanisamy, S.; Ku, S.; Chen, S. M. Microchim. Acta 2013 , 180 , 1037-1042.
Guler, M.; Turkoglu, V.; Kivrak, A.; Karahan, F. Mater. Sci. Eng. C 2018 , 90 , 454-460.
Huang, J.; Liu, Y.; Hou, H.; You, T. Biosens. Bioelectron. 2008 , 24 , 632-637.
Bulut, A.; Yurderi, M.; Karatas, Y.; Zahmakiran, M.; Kivrak, H.; Gulcan, M.; Kaya, M. Appl. Catal. B: Environ. 2015 , 164 , 324-333.