Saadieh MOHAJER, Robabeh BAHARFAR

5627

Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino reactions

A series of novel 2,5-dioxopyrrolidines were synthesized by the one-pot reaction of coumarin-3-carboxylic acids 1 with thiourea derivatives and alkyl isocyanides in the presence of Fe$_{3}$O$_{4}$ NPs @ lipase as heterogeneous reusable nanobiocatalysts with high yields.
Keywords:

Diastereoselective synthesis, 2 5-dioxopyrrolidine derivatives, biocatalytic reactions,

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Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
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