Holstein İneklerde GH/AluI Polimorfizmi ile Bazı Süt Verim Özellikleri Arasındaki İlişkiler

Bu çalışmanın amacı, organik yetiştirilen 115 baş Holstein ırkı inekten oluşan sürüde Büyüme Hormon (GH) geni bakımından genotip ve allel frekanslarınının dağılımını belirlemek, genetik varyasyonu ortaya koymak ve bazı süt verim özellikleri arasındaki ilişkileri araştırmaktır. Elde edilen bulgular sonucunda, çalışılan sığır populasyonunun GH geni LL, LV ve VV genotip frekanslarının sırasıyla 0,41, 0,49, ve 0,10 olarak bulunduğu ve Hardy-Weinberg eşitliği testine göre dengede olduğu görülmüştür. Laktasyon süt verimi ortalamaları LL, LV ve VV genotipleri için sırasıyla 7136 kg, 7470 kg ve 8017 kg olarak tespit edilmiştir. Genotiplere ait incelenen Laktasyon süt verimi, 305 günlük süt verimi, Pik süt verimi ve Laktasyon uzunluğu ortalamaları arasında istatistiksel olarak anlamlı ilişki bulunamamıştır. Çalışmada GH/AluI polimorfizminin sığırların süt verim özelliklerinin ıslahı için tek başına yeterli olmadığı görülmüştür

Relationships between GH/AluI Polymorphism and Some Performance Traits in Holstein Cows

The aim of this study is to determine the genotype and allelic frequencies of Growth Hormone (GH) gene, to present the genetic variation, and to research the relationships between the GH genotypes and some milk production traits of 115 organically grown Holstein cows. It was seen that GH gene LL, LV ve VV genotype frequencies is 0.41, 0.49, ve 0.10 respectively, and is stable according to Hardy-Weinberg equilibrium genetic balance test in the cattle population. Moreover, Lactation milk yield averages were found to be 7136 kg, 7470 kg and 8017 kg for the LL, LV and VV genotypes, respectively. There was no statistically significant relationship between the actual lactation milk yield, 305d milk yield, peak daily yield, lactation length averages of different genotypes. In the study, GH/AluI polymorphism was found to be insufficient for improvement of the milk yield traits alone

___

  • Bass JJ, Oldham JM, Hodgkinson SC, Fowke PJ, Sauerwein H, Molan P, Breier BH, Gluckman PD. 1991. Influence of nutrition and bovine growth hormone (GH) on hepatic GH binding, insulin-like growth factor-I and growth of lambs. J. Endocrinol, 128(2): 181-186.
  • Bauman DE. 1992. Bovine somatotropin: review of an emerging animal technology. J. Dairy Sci. 75 (12): 3432-3451.
  • Chrenek P, Kmet J, Sakowski T, Vasicek D, Huba J, Chrenek J. 1998. Relationships of growth hormone genotypes with meat production traits of Slovak Pied bulls. Czech J. Anim. Sci., 43(12): 541-544.
  • Drogemuller C, Hamann H, Distl O. 2001. Candidate gene markers for litter size in different German pig lines. J. Anim. Sci., 79: 2565-2570.
  • Dybus A. 2002. Associations between Leu/Val polymorphism of growth hormone gene and milk production traits in Blackand-White cattle. Arch. Tierzucht Dummerstorf, 45 (5): 421- 428.
  • Falaki M, Gengler N, Sneyers M, Prandi A, Massart S, Formigoni A, Burny A, Portetelle D, Renaville R. 1996. Relationships of polymorphisms for growth hormone and growth hormone receptor genes with milk production traits for Italian Holstein-Friesian bulls. J. Dairy Sci.79(8):1446- 1453.
  • Fries R, Eggen A, Womack JE. 1993. The bovine genome map. Mamm. Genome., 4: 405-428.
  • Ge W, Davis ME, Hines HC, Irvin KM, Simmen CM. 2003. Association of single nucleotide polymorphisms in the growth hormone and growth hormone receptor genes with serum insulin-like growth factor I concentration and growth traits in Angus cattle. J. Anim. Sci., 81: 641-648.
  • Grochowska R, Zwierzchowski L. Snochowski M, Reklewski Z. 1999. Stimulated growth hormone (GH) release in Friesian cattle with respect to GH genotypes. Reproduction Nutrition Development 39 (2): 171-180. Abst.
  • Grochowska R, Lunden A, Zwierzchowski L, Snochowski M, Oprzadek J. 2001. Association between gene polymorphism of growth hormone and carcass traits in dairy bulls. Anim. Sci., 72: 441-447.
  • Kovacs K, Volgyi-Csik J, Zsolnai A, Gyorkos I, Fesus L. 2006. Associations between the AluI polymorphism of growth hormone gene and production and reproduction traits in a Hungarian Holstein-Friesian bull dam population. Arch. Anim. Breed., 49(3): 236-249.
  • Lucy MC, Hauser SD, Eppard PJ, Krivi GG, Clark JH, Bauman DE, Collier RJ. 1993. Variants of somatotropin in cattlegene frequencies in major dairy breeds and associated milkproduction. Domest. Anim. Endocrinol., 10(4): 325-333. Abst.
  • Özdemir M. 2011. Determination of allele frequencies of growth hormone AluI polymorphism in Brown Swiss, Holstein, native East Anatolian Red and Turkish Grey breeds. International Journal of Dairy Technology. 64(3): 350-352.
  • Ozdemir M, Topal M, Aksakal V. 2018. The relationships between performance traits and the bGH/AluI and Pit1/HinfI polymorphisms in Holstein cows. Indian J. Anim. Res., 52(2): 186-191.
  • Özkan E, Soysal Mİ, Dinç H, Sönmez G, Okyar M, Togan İ. 2009. Türkiye sığır ırklarında büyüme hormonu AluI ve MspI polimorfizminin PZR-RFLP yönteminin kullanılarak belirlenmesi. 6. Ulusal Zootekni Kongresi, 24-26 Haziran, Erzurum, 93-102.
  • Schlee P, Graml R, Rottmann O, Pirchner F. 1994. Influence of growth hormone genotypes on breeding values of Simmental bulls. Journal of Animal Breeding and Genetics, 111: 253-256.
  • Sejrsen K, Foldager J, Sorensen MT, Akers RM, Bauman DE. 1986. Effect of exogenous bovine somatotropin on pubertal mammary development in heifers. J. Dairy Sci. 69(6): 1528- 1535.
  • Sönmez Z, Özdemir M, Aksakal V. 2017. Büyüme Hormonu Geni Polimorfizminin Buzağı Doğum Ağırlığı Üzerine Etkisi. Türk Tarım-Gıda Bilim ve Teknoloji Dergisi, 5(13): 1781-1784.
  • Tambasco DD, Paz CCP, Tambasco-Studart MD, Pereira AP, Alencar MM, Freita AR, Coutinho LL, Packer IU, Regitano
  • LCA. 2003. Candidate genes for growth traits inbeef cattle crosses Bos taurus x Bos indicus. J Anim. Breed. Genet., 120: 51-56.
  • Unanian MM, Barreto CC, Freitas AR, Cordeiro CMT, Josahkian LA. 2000. Association of growth hormone gene polymorphisms with weight traits in Nelore breed. Rev. Bras. Zootec. 29: 1380-1386.
  • Vasconcellos LPMK, Tambasco DD, Pereira AP, Coutinho LL, Regitano LCA. 2003. Genetic characterization of Aberdeen Angus cattle using molecular markers. Genetics and Molecular Biology. 26(2): 133-137.
  • Yao J, Aggrey SE, Zadworny D, Hayes JF, Kuhnlein U. 1996. Sequence variations in the bovine growth hormone gene characterized by single-strand conformation polymorphins (SSCP) analysis and their association with milk production traits in Holsteins. Genetics., 144: 1809-1816.
Türk Tarım - Gıda Bilim ve Teknoloji dergisi-Cover
  • ISSN: 2148-127X
  • Yayın Aralığı: Aylık
  • Başlangıç: 2013
  • Yayıncı: Turkish Science and Technology Publishing (TURSTEP)