Tezcan AKIN, Serhat OCAKLI, Gizem GÜNEŞ, İbrahim DOĞAN, Merve AKIN, Erdinç ÇETİNKAYA, Hüseyin BERKEM, Sadettin ER, Mesut TEZ

THE MODIFIED SYSTEMIC INFLAMMATION SCORE CAN BE USED TO PREDICT THE PRESENCE OF INVASIVE CARCINOMA IN COLORECTAL POLYPS WITH HIGH-GRADE DYSPLASIA

In recent years, the prognostic and predictive values of scoring systems such as systemic inflammation score (SIS) and modified systemic inflammation score (mSIS) have been investigated in colorectal cancers. To investigate the efficacy of the modified systemic inflammatory score (mSIS) calculated by simple laboratory tests in predicting the presence of invasive carcinoma in colon polyps with high-gradedysplasia (HGD).The postoperative data of 44 patients with colorectal polyps who underwent surgery with the diagnosis of preoperative HGD between January 2019 and October 2021 were retrospectively analyzed. According to the results of the postoperativehistopathological examination, the patients were divided into two groups as HGD/intramucosal carsinom (Tis)/adenomatous polyp and invasive carcinoma. mSIS calculation was made as follows: mSIS 0 [albumin (ALB)≥4.0 g/dL and lymphocyte/monocyte ratio (LMR)≥3.4], mSIS 1 (ALB

MODİFİYE SİSTEMİK İNFLAMASYON SKORU YÜKSEK DERECE DİSPLAZİLİ KOLOREKTAL POLİPLERDE İNVAZİV KARSİNOM VARLIĞINI ÖNGÖRMEDE KULLANILABİLİR

Son yıllarda sistemik inflamasyon skor (SIS) ve modifiye sistemik inflamasyon skor (mSIS) gibi skorların kolorektal kanserlerde prognostik ve prediktif değerleri araştırılmıştır. Bu çalışmada, basit labaratuvar testleri ile hesaplanan modifiye sistemik inflamatuar skorun (mSIS) high grade displazili (HGD) kolon poliplerinde invaziv karsinom varlığını öngörmedeki etkinliği araştırıldı. Ocak 2019 -Ekim 2021 tarihleri arasında preoperatif HGD tanısıyla opere edilen 44 kolorektal polipli hastanın postoperatif verileri retrospektif olarak incelendi. Hastalar postoperatif histopatolojik inceleme sonuçlarına göre HGD, Tis veya adenomatöz polip ve invaziv karsinom olarak iki gruba ayrıldı. mSIS hesaplaması; mSIS 0 [albümin (ALB) ≥ 4.0 g/dL ve lenfosit/monosit oranı (LMR) ≥ 3.4], mSIS 1 (ALB

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