Clinical Evaluation of Children with Kawasaki Disease Hospitalized in Our Clinic: A Retrospective Study

Objective: Kawasaki disease is one of the most common childhood forms of vasculitis. The aim of this study was to evaluate children with Kawasaki disease hospitalized in our pediatrics department over a 6-year period.Methods: A total of 39 children treated for Kawasaki disease in the pediatric department between January 2008 and December 2013 were evaluated retrospectively.Results: Of 39 patients, 29 (74.3%) were male and 10 (25.6%) were female. The male/female ratio was 2.9. The mean patient age was 31.82±20.31 months. In all, 2 patients were diagnosed with Kawasaki disease in 2008, 6 in 2009, 5 in 2010, 7 in 2011, 10 in 2012 and 9 in 2013. Lesions of the oral cavity were found in 89.7%, extremity changes were observed in 61.5%, conjunctivitis was seen in 76.9%, polymorphous exanthema was detected in 74.4%, and lymphadenopathy was present in 61.5% of the patients. In 22 patients, coronary artery disease was detected on an echocardiogram. According to the Kawasaki disease diagnostic criteria, 64.1% were diagnosed as complete Kawasaki disease and 35.9% as incomplete. Myocardial infarction or death did not occur.Conclusion: The cardiovascular complications of Kawasaki disease can be prevented with early diagnosis and treatment in both complete and incomplete cases

Kaynakça

1. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi 1967;16:178–222.

2. Aykan HH, Özkutlu S. Kawasaki Hastalığı. In: Yurdakök M, editor. Yurdakök Pediatri. Ankar: Güneş Tıp Kitabevi; 2017. p. 3215–24.

3. Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 2004;110:2747–71.

4. Park MK. Kawasaki Disease. Pediatric Cardiology for Practitioners. 5th ed. Philedelphia: Mosby Elsevier; 2008. p. 367–76.

5. American Academy of Pediatrics. Kawasaki Disease. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, editors. Red Book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village: American Academy of Pediatrics; 2015. p. 667–76.

6. Tizard EJ, Suzuki A, Levin M, Dillon MJ. Clinical aspects of 100 patients with Kawasaki disease. Arch Dis Child 1991;66:185–8.

7. Burns JC, Capparelli EV, Brown JA, Newburger JW, Glode MP. Intravenous gamma-globulin treatment and retreatment in Kawasaki disease. US/Canadian Kawasaki Syndrome Study Group. Pediatr Infect Dis J 1998;17:1144–8.

8. Rowley AH, Gonzalez-Crussi F, Shulman ST. Kawasaki syndrome. Rev Infect Dis 1988;10:1–15.

9. Scott JS, Ettedgui JA, Neches WH. Cost-effective use of echocardiography in children with Kawasaki disease. Pediatrics 1999;104:e57.

10. Lee MH, Dai ZK, Lee MS, Hsu JH, Chuang HY, Wu JR. The recommended frequency of echocardiography in follow-up evaluation of patients with Kawasaki disease. Acta Paediatr Taiwan 2005;46:346–51.

11. Arat C, Acar Y, Türkmenoğlu Y, Sayar T, Hamilçıkan SB, Sazak S, et al. Kawasaki disease: review of 21 cases. Cukurova Med J 2016;41:97–104.

12. İnalhan M DS, Oral M, Temel Ö, Ünlütürk Ö, Seren LP, Savaş İ. Kawasaki Hastalığı Tanılı Olgularımızın Değerlendirilmesi. Ege Pediatri Bülteni 2006; 3:9–14.

13. Topçu S, Akgün Doğan Ö, Öz N, Tanır G. Clinical Evaluations of 49 Cases with Kawasaki Disease: A Retrospective Cohort Study. J Pediatr Inf 2014;8:64–70.

14. Ece A, Guneş A, Tan İ, Uluca U, Kelekci S, Yel S, et al. Kawasaki disease: Evaluation of 13 cases. Dicle Tıp Dergisi 2013;40:95–9.

15. Ozyurek R, Levent E, Ulger Z, Gurses D. Kawasaki Hastalığı: 11 vakanın degerlendirilmesi. Çocuk Sağlığı ve Hastalıkları Dergisi 2004;47:167–71.

16. Binnetoğlu K, Kuşdal Y, Altun G, Babaoğlu K. The Clinical and Epi demiologic Features of Kawasaki Disease in Kocaeli Region: Results of 24 Patients. Çocuk Enf Derg 2010;4:71–5.

17. Kayiran SM, Dindar A, Gurakan B. An evaluation of children with Kawasaki disease in Istanbul: a retrospective follow-up study. Clinics (Sao Paulo) 2010;65:1261–5.

18. Alexopoulos A, Vekiou A, Lycopoulou L, Tavena A, Lagona E, Kakourou T. Kawasaki disease in Greek children: a retrospective study. J Eur Acad Dermatol Venereol 2013;27:580–8.

19. Perrin L, Letierce A, Guitton C, Tran TA, Lambert V, Koné-Paut I. Comparative study of complete versus incomplete Kawasaki disease in 59 pediatric patients. Joint Bone Spine 2009;76:481–5.

20. Al-Harbi KM. Kawasaki disease in Western Saudi Arabia. Saudi Med J 2010;31:1217–20.

21. Kanra G CA, Kara A, Seçmeer G, Ceyhan M. Kawasaki Hastalığı: Dokuz vakanın takdimi. Çocuk Sağlığı ve Hastalıkları Dergisi 1999;42:469–78.

22. Ozdemir H, Ciftçi E, Tapisiz A, Ince E, Tutar E, Atalay S, et al. Clinical and epidemiological characteristics of children with Kawasaki disease in Turkey. J Trop Pediatr 2010;56:260–2.

23. Ergüven M. Yasa O, Kral A, Bulut Ö. Evaluation of Epidemiological, Laboratory Measure- ments, Clinical and Prognostic Features, Treatments and Echocardiographies of Our Patients with Kawasaki Disease. Çocuk Dergisi 2010;10:86–9.

24. Kawasaki T. Kawasaki disease. Acta Paediatr 1995;84:713–5.

25. Bhatnagar SK, Paul G, Subramanian R, Al Hosni MS, Al Khusaiby SM. Kawasaki disease in Oman-a clinical study. J Trop Pediatr 2003;49:361–6.

26. Kim DS. Kawasaki disease. Yonsei Med J 2006;47:759–72.

Kaynak Göster

Southern Clinics of Istanbul Eurasia
  • ISSN: 2587-0998
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2017

990344

Sayıdaki Diğer Makaleler

Efficacy and Safety of Prophylactic Intracameral Gatifloxacin Injection in Cataract Surgery: 1 Year Results

Ayşegül PENBE, Işıl Kutlutürk KARAGÖZ, Mehmet ATAKAN, Yusuf ÖZERTÜRK

Comparison of the Transepicondylar Axis Measured Using Computed Tomography Before Primary Total Knee Arthroplasty and the Surgical Measurement

Zeki TAŞDEMİR, Güven BULUT, Özgür BAYSAL, Hüseyin Bilğehan ÇEVİK, Nurzat ELMALI

Retrospective Analysis of Patients Treated for Volatile Substance Burn Injuries

Yücel YÜCE, Banu Eler ÇEVİK, Kutlu Hakan ERKAL

A Rare Localization of Recurrent Pleomorphic Adenoma: The Maxillary Sinus

Cem Berkay SINACI, Sultan YALÇIN, Gaye Taylan FİLİNTE, KAAN GİDEROĞLU, Celal ALİOĞLU

Preoperative Evaluation of Internet Usage Characteristics of Patients in an Anesthesiology Clinic: A Survey of 1000 Patients

Banu Eler ÇEVİK, Yücel YÜCE, Kutlu Hakan ERKAL

Evaluation of Controlled Ovarian Hyperstimulation Gonadotropin Stimulation and Clomiphene Citrate Stimulation Cycles in Infertile Women

Yasemin ODABAŞ, Bülent KARS, Önder SAKİN, ENGİN ERSİN ŞİMŞEK

Retroperitoneal Giant Mixed Adenoneuroendocrine Carcinoma Case Report

NEJDET BİLDİK, Selçuk KAYA, LEVENT KAPTANOĞLU, METİN KEMENT, Yunus Emre ALTUNTAŞ, Önder ALTIN, Ahmet Feran AĞAÇHAN, HASAN FEHMİ KÜÇÜK

Diagnostic Value of Endometrial Nerve Endometrial Tissue of Patients with Endometriosis

Yaren Tuba BEKTAŞ, Önder SAKİN, ZEHRA MELTEM PİRİMOĞLU, Aylin Onan YILMAZ, Kayhan BAŞAK, ESRA ESİM BÜYÜKBAYRAK, Sadullah ÖZKAN, ENGİN ERSİN ŞİMŞEK

Clinical Evaluation of Children with Kawasaki Disease Hospitalized in Our Clinic: A Retrospective Study

Mehmet GÜNDÜZ, Yasemin AKIN, Esra Çelik KUZAYTEPE, Ayşe KARAASLAN, Esra Çetinkaya POLATOĞLU, Hüseyin KIYAK

Endoscopic Treatment of Boerhaave Syndrome: A case Report

Mustafa Salih AKIN, MEHMET SAİT BUĞDACI, Esin KORKUT